Hooman Hefzi
Title
Cited by
Cited by
Year
Sensory maps in the olfactory cortex defined by long-range viral tracing of single neurons
S Ghosh, SD Larson, H Hefzi, Z Marnoy, T Cutforth, K Dokka, KK Baldwin
Nature 472 (7342), 217-220, 2011
2082011
Recon 2.2: from reconstruction to model of human metabolism
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12 (7), 109, 2016
1762016
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell Systems 3 (5), 434-443. e8, 2016
1222016
Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow
A Golabgir, JM Gutierrez, H Hefzi, S Li, BO Palsson, C Herwig, NE Lewis
Biotechnology advances 34 (5), 621-633, 2016
302016
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
JM Gutierrez, A Feizi, S Li, TB Kallehauge, H Hefzi, LM Grav, D Ley, ...
Nature communications 11 (1), 1-10, 2020
122020
Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow
E Brunk, RL Chang, J Xia, H Hefzi, JT Yurkovich, D Kim, E Buckmiller, ...
Proceedings of the National Academy of Sciences 115 (43), 11096-11101, 2018
112018
Functional interrogation of Plasmodium genus metabolism identifies species-and stage-specific differences in nutrient essentiality and drug targeting
AM Abdel-Haleem, H Hefzi, K Mineta, X Gao, T Gojobori, BO Palsson, ...
PLoS computational biology 14 (1), e1005895, 2018
92018
WormJam: A consensus C. elegans Metabolic Reconstruction and Metabolomics Community and Workshop Series
J Hastings, A Mains, M Artal-Sanz, S Bergmann, BP Braeckman, J Bundy, ...
Worm 6 (2), e1373939, 2017
92017
From random mutagenesis to systems biology in metabolic engineering of mammalian cells
H Hefzi, NE Lewis
Pharmaceutical Bioprocessing 2 (5), 355-358, 2014
92014
Systematic evaluation of site-specific recombinant gene expression for programmable mammalian cell engineering
N Pristovsek, S Nallapareddy, LM Grav, H Hefzi, NE Lewis, P Rugbjerg, ...
ACS synthetic biology 8 (4), 758-774, 2019
62019
Awakening dormant glycosyltransferases in CHO cells with CRISPRa
KJC Karottki, H Hefzi, K Xiong, I Shamie, AH Hansen, S Li, LE Pedersen, ...
Biotechnology and Bioengineering 117 (2), 593-598, 2020
52020
Reprogramming AA catabolism in CHO cells with CRISPR/Cas9 genome editing improves cell growth and reduces byproduct secretion
D Ley, S Pereira, LE Pedersen, J Arnsdorf, H Hefzi, AM Davy, TK Ha, ...
Metabolic engineering 56, 120-129, 2019
22019
Reconstruction of Genome-Scale Metabolic Networks
H Hefzi, BO Palsson, NE Lewis
Handbook of Systems Biology, 229-250, 2013
22013
Systemic post-translational control of bacterial metabolism regulates adaptation in dynamic environments
E Brunk, RL Chang, J Xia, H Hefzi, JT Yurkovich, D Kim, E Buckmiller, ...
Available at SSRN 3155551, 2018
12018
Using targeted genome integration for virus-free genome-wide mammalian CRISPR screen
K Xiong, KJLC Karottki, H Hefzi, S Li, LM Grav, S Li, P Spahn, JS Lee, ...
bioRxiv, 2020
2020
A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes
KJ la Cour Karottki, H Hefzi, S Li, LE Pedersen, P Spahn, D Ruckerbauer, ...
bioRxiv, 2020
2020
Mammalian cells devoid of lactate dehydrogenase activity
H Hefzi, NE Lewis
US Patent App. 16/096,784, 2019
2019
TARGETING SNPs IN DNA REPAIR GENES: TOWARDS GENOME STABILIZATION IN CHINESE HAMSTER OVARY (CHO) CELL LINES
PN Spahn, H Hefzi, S Li, NE Lewis
MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018
2018
Elimination of the “Essential” Warburg effect in CHO cells through a multiplex genome engineering strategy
NE Lewis, H Hefzi, SM Noh, IM Monge, N Pristovsek, B Voldborg, ...
2018
Engineering CHO cells for the production of" Hard-To-Produce" proteins
B Voldborg, S Kol, J Arnsdorf, A Holmgaard Hansen, T Wulf, M Decker, ...
2018
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Articles 1–20