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Polly Fordyce
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Year
Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro
MT Valentine, PM Fordyce, TC Krzysiak, SP Gilbert, SM Block
Nature cell biology 8 (5), 470-476, 2006
3042006
Simultaneous, coincident optical trapping and single-molecule fluorescence
MJ Lang, PM Fordyce, AM Engh, KC Neuman, SM Block
Nature methods 1 (2), 133-139, 2004
2972004
Stepping and stretching: how kinesin uses internal strain to walk processively
SS Rosenfeld, PM Fordyce, GM Jefferson, PH King, SM Block
Journal of Biological Chemistry 278 (20), 18550-18556, 2003
2282003
De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis
PM Fordyce, D Gerber, D Tran, J Zheng, H Li, JL DeRisi, SR Quake
Nature biotechnology 28 (9), 970-975, 2010
2102010
Eg5 steps it up!
MT Valentine, PM Fordyce, SM Block
Cell Division 1, 1-8, 2006
1562006
High-throughput chromatin accessibility profiling at single-cell resolution
A Mezger, S Klemm, I Mann, K Brower, A Mir, M Bostick, A Farmer, ...
Nature communications 9 (1), 3647, 2018
1492018
Structure of the transcriptional network controlling white‐opaque switching in Candida albicans
AD Hernday, MB Lohse, PM Fordyce, CJ Nobile, JL DeRisi, AD Johnson
Molecular microbiology 90 (1), 22-35, 2013
1402013
Combined optical trapping and single-molecule fluorescence
MJ Lang, PM Fordyce, SM Block
Journal of biology 2 (1), 1-4, 2003
1332003
Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics
CJ Markin, DA Mokhtari, F Sunden, MJ Appel, E Akiva, SA Longwell, ...
Science 373 (6553), eabf8761, 2021
992021
Programmable microfluidic synthesis of spectrally encoded microspheres
RE Gerver, R Gómez-Sjöberg, BC Baxter, KS Thorn, PM Fordyce, ...
Lab on a Chip 12 (22), 4716-4723, 2012
842012
Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains
MB Lohse, AD Hernday, PM Fordyce, L Noiman, TR Sorrells, ...
Proceedings of the National Academy of Sciences 110 (19), 7660-7665, 2013
832013
Discovering epistatic feature interactions from neural network models of regulatory DNA sequences
P Greenside, T Shimko, P Fordyce, A Kundaje
Bioinformatics 34 (17), i629-i637, 2018
782018
Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding
DD Le, TC Shimko, AK Aditham, AM Keys, SA Longwell, Y Orenstein, ...
Proceedings of the National Academy of Sciences 115 (16), E3702-E3711, 2018
762018
Systematic characterization of feature dimensions and closing pressures for microfluidic valves produced via photoresist reflow
PM Fordyce, CA Diaz-Botia, JL DeRisi, R Gomez-Sjoberg
Lab on a Chip 12 (21), 4287-4295, 2012
742012
Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses
PM Fordyce, D Pincus, P Kimmig, CS Nelson, H El-Samad, P Walter, ...
Proceedings of the National Academy of Sciences 109 (45), E3084-E3093, 2012
702012
Double emulsion flow cytometry with high-throughput single droplet isolation and nucleic acid recovery
KK Brower, C Carswell-Crumpton, S Klemm, B Cruz, G Kim, SGK Calhoun, ...
Lab on a Chip 20 (12), 2062-2074, 2020
692020
Programmable microfluidic synthesis of over one thousand uniquely identifiable spectral codes
HQ Nguyen, BC Baxter, K Brower, CA Diaz‐Botia, JL DeRisi, PM Fordyce, ...
Advanced optical materials 5 (3), 1600548, 2017
592017
How duplicated transcription regulators can diversify to govern the expression of nonoverlapping sets of genes
JC Pérez, PM Fordyce, MB Lohse, V Hanson-Smith, JL DeRisi, ...
Genes & development 28 (12), 1272-1277, 2014
522014
Tuning T cell receptor sensitivity through catch bond engineering
X Zhao, EM Kolawole, W Chan, Y Feng, X Yang, MH Gee, KM Jude, ...
Science 376 (6589), eabl5282, 2022
512022
Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads
HQ Nguyen, J Roy, B Harink, NP Damle, NR Latorraca, BC Baxter, ...
elife 8, e40499, 2019
482019
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