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Polly Fordyce
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Year
Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro
MT Valentine, PM Fordyce, TC Krzysiak, SP Gilbert, SM Block
Nature cell biology 8 (5), 470-476, 2006
3092006
Simultaneous, coincident optical trapping and single-molecule fluorescence
MJ Lang, PM Fordyce, AM Engh, KC Neuman, SM Block
Nature methods 1 (2), 133-139, 2004
3032004
Stepping and stretching: how kinesin uses internal strain to walk processively
SS Rosenfeld, PM Fordyce, GM Jefferson, PH King, SM Block
Journal of Biological Chemistry 278 (20), 18550-18556, 2003
2372003
De novo identification and biophysical characterization of transcription-factor binding sites with microfluidic affinity analysis
PM Fordyce, D Gerber, D Tran, J Zheng, H Li, JL DeRisi, SR Quake
Nature biotechnology 28 (9), 970-975, 2010
2262010
High-throughput chromatin accessibility profiling at single-cell resolution
A Mezger, S Klemm, I Mann, K Brower, A Mir, M Bostick, A Farmer, ...
Nature communications 9 (1), 3647, 2018
1682018
Eg5 steps it up!
MT Valentine, PM Fordyce, SM Block
Cell division 1, 1-8, 2006
1632006
Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics
CJ Markin, DA Mokhtari, F Sunden, MJ Appel, E Akiva, SA Longwell, ...
Science 373 (6553), eabf8761, 2021
1482021
Structure of the transcriptional network controlling white‐opaque switching in Candida albicans
AD Hernday, MB Lohse, PM Fordyce, CJ Nobile, JL DeRisi, AD Johnson
Molecular microbiology 90 (1), 22-35, 2013
1472013
Combined optical trapping and single-molecule fluorescence
MJ Lang, PM Fordyce, SM Block
Journal of biology 2, 1-4, 2003
1322003
Discovering epistatic feature interactions from neural network models of regulatory DNA sequences
P Greenside, T Shimko, P Fordyce, A Kundaje
Bioinformatics 34 (17), i629-i637, 2018
912018
Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains
MB Lohse, AD Hernday, PM Fordyce, L Noiman, TR Sorrells, ...
Proceedings of the National Academy of Sciences 110 (19), 7660-7665, 2013
912013
Programmable microfluidic synthesis of spectrally encoded microspheres
RE Gerver, R Gómez-Sjöberg, BC Baxter, KS Thorn, PM Fordyce, ...
Lab on a Chip 12 (22), 4716-4723, 2012
902012
Double emulsion flow cytometry with high-throughput single droplet isolation and nucleic acid recovery
KK Brower, C Carswell-Crumpton, S Klemm, B Cruz, G Kim, SGK Calhoun, ...
Lab on a Chip 20 (12), 2062-2074, 2020
862020
Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding
DD Le, TC Shimko, AK Aditham, AM Keys, SA Longwell, Y Orenstein, ...
Proceedings of the National Academy of Sciences 115 (16), E3702-E3711, 2018
852018
Tuning T cell receptor sensitivity through catch bond engineering
X Zhao, EM Kolawole, W Chan, Y Feng, X Yang, MH Gee, KM Jude, ...
Science 376 (6589), eabl5282, 2022
842022
Short tandem repeats bind transcription factors to tune eukaryotic gene expression
CA Horton, AM Alexandari, MGB Hayes, E Marklund, JM Schaepe, ...
Science 381 (6664), eadd1250, 2023
822023
Systematic characterization of feature dimensions and closing pressures for microfluidic valves produced via photoresist reflow
PM Fordyce, CA Diaz-Botia, JL DeRisi, R Gomez-Sjoberg
Lab on a Chip 12 (21), 4287-4295, 2012
792012
Large-scale mapping and mutagenesis of human transcriptional effector domains
N DelRosso, J Tycko, P Suzuki, C Andrews, Aradhana, A Mukund, ...
Nature 616 (7956), 365-372, 2023
762023
Machine learning for microfluidic design and control
D McIntyre, A Lashkaripour, P Fordyce, D Densmore
Lab on a Chip 22 (16), 2925-2937, 2022
762022
Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses
PM Fordyce, D Pincus, P Kimmig, CS Nelson, H El-Samad, P Walter, ...
Proceedings of the National Academy of Sciences 109 (45), E3084-E3093, 2012
762012
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Articles 1–20