Denis Shields
Denis Shields
Professor of Clinical Bioinformatics, University College Dublin
Verified email at - Homepage
Cited by
Cited by
Molecular evidence for an ancient duplication of the entire yeast genome
KH Wolfe, DC Shields
Nature 387 (6634), 708-713, 1997
Codon usage patterns in Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Drosophila melanogaster and Homo sapiens; a review of the …
PM Sharp, E Cowe, DG Higgins, DC Shields, KH Wolfe, F Wright
Nucleic acids research 16 (17), 8207-8211, 1988
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ...
Nature genetics 50 (10), 1412-1425, 2018
" Silent" sites in Drosophila genes are not neutral: evidence of selection among synonymous codons.
DC Shields, PM Sharp, DG Higgins, F Wright
Molecular biology and evolution 5 (6), 704-716, 1988
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
HR Warren, E Evangelou, CP Cabrera, H Gao, M Ren, B Mifsud, I Ntalla, ...
Nature genetics 49 (3), 403-415, 2017
Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus
W Yang, N Shen, DQ Ye, Q Liu, Y Zhang, XX Qian, N Hirankarn, D Ying, ...
PLoS genetics 6 (2), e1000841, 2010
A genetic defect in 5, 10 methylenetetrahydrofolate reductase in neural tube defects
AS Whitehead, P Gallagher, JL Mills, PN Kirke, H Burke, AM Molloy, ...
QJM: An International Journal of Medicine 88 (11), 763-766, 1995
Genome-Wide Association Study of Blood Pressure Extremes Identifies Variant near UMOD Associated with Hypertension
S Padmanabhan, O Melander, T Johnson, AM Di Blasio, WK Lee, ...
PLoS genetics 6 (10), e1001177, 2010
Integration of proteomics and genomics in platelets: a profile of platelet proteins and platelet-specific genes
JP McRedmond, SD Park, DF Reilly, JA Coppinger, PB Maguire, ...
Molecular & Cellular Proteomics 3 (2), 133-144, 2004
Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations
DL Harmon, DC Shields, JV Woodside, D McMaster, JWG Yarnell, ...
Genetic Epidemiology: The Official Publication of the International Genetic …, 1999
Synonymous codon usage in Bacillus subtilis reflects both translational selection and mutational biases
DC Shields, PM Sharp
Nucleic acids research 15 (19), 8023-8040, 1987
Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders
M Den Hoed, M Eijgelsheim, T Esko, BJJM Brundel, DS Peal, DM Evans, ...
Nature genetics 45 (6), 621-631, 2013
Homocysteine and risk of premature coronary heart disease: evidence for a common gene mutation
PM Gallagher, R Meleady, DC Shields, KS Tan, D McMaster, R Rozen, ...
Circulation 94 (9), 2154-2158, 1996
Cyclooxygenase‐1 haplotype modulates platelet response to aspirin
AO Maree, RJ Curtin, A Chubb, C Dolan, D Cox, J O'brien, P Crean, ...
Journal of Thrombosis and Haemostasis 3 (10), 2340-2345, 2005
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci
FW Asselbergs, Y Guo, EPA Van Iperen, S Sivapalaratnam, V Tragante, ...
The American Journal of Human Genetics 91 (5), 823-838, 2012
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
R Saxena, CC Elbers, Y Guo, I Peter, TR Gaunt, JL Mega, MB Lanktree, ...
The American Journal of Human Genetics 90 (3), 410-425, 2012
The “thermolabile” variant of methylenetetrahydrofolate reductase and neural tube defects: an evaluation of genetic risk and the relative importance of the genotypes of the …
DC Shields, PN Kirke, JL Mills, D Ramsbottom, AM Molloy, H Burke, ...
The American journal of human genetics 64 (4), 1045-1055, 1999
Towards the improved discovery and design of functional peptides: common features of diverse classes permit generalized prediction of bioactivity
C Mooney, NJ Haslam, G Pollastri, DC Shields
Public Library of Science 7 (10), e45012, 2012
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins
I Postmus, S Trompet, HA Deshmukh, MR Barnes, X Li, HR Warren, ...
Nature communications 5 (1), 1-10, 2014
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip
PJ Talmud, F Drenos, S Shah, T Shah, J Palmen, C Verzilli, TR Gaunt, ...
The American journal of human genetics 85 (5), 628-642, 2009
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