Ali Ryan
Ali Ryan
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Cited by
Cited by
Effect of detergent on “promiscuous” inhibitors
AJ Ryan, NM Gray, PN Lowe, C Chung
Journal of medicinal chemistry 46 (16), 3448-3451, 2003
Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin
AJ Ryan, J Ghuman, PA Zunszain, C Chung, S Curry
Journal of structural biology 174 (1), 84-91, 2011
Arylamine N‐acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery
E Sim, A Abuhammad, A Ryan
British journal of pharmacology 171 (11), 2705-2725, 2014
A novel mechanism for azoreduction
A Ryan, N Laurieri, I Westwood, CJ Wang, E Lowe, E Sim
Journal of molecular biology 400 (1), 24-37, 2010
Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases
A Ryan, CJ Wang, N Laurieri, I Westwood, E Sim
Protein & cell 1 (8), 780-790, 2010
Identification of NAD (P) H quinone oxidoreductase activity in azoreductases from P. aeruginosa: azoreductases and NAD (P) H quinone oxidoreductases belong to the same FMN …
A Ryan, E Kaplan, JC Nebel, E Polycarpou, V Crescente, E Lowe, ...
PloS one 9 (6), e98551, 2014
Crystallographic analysis reveals the structural basis of the high-affinity binding of iophenoxic acid to human serum albumin
AJ Ryan, C Chung, S Curry
BMC structural biology 11 (1), 18, 2011
Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide
CJ Wang, N Laurieri, A Abuhammad, E Lowe, I Westwood, A Ryan, E Sim
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010
Activation of nitrofurazone by azoreductases: multiple activities in one enzyme
A Ryan, E Kaplan, N Laurieri, E Lowe, E Sim
Scientific reports 1, 63, 2011
Azoreductases in drug metabolism
A Ryan
British Journal of Pharmacology 174 (14), 2161-2173, 2017
Use of long-term monitoring data to evaluate benzene, MTBE, and TBA plume behavior in groundwater at retail gasoline sites
R Kamath, JA Connor, TE McHugh, A Nemir, MP Le, AJ Ryan
Journal of Environmental Engineering 138 (4), 458-469, 2012
Primary sequence contribution to the optical function of the eye lens
K Mahendiran, C Elie, JC Nebel, A Ryan, BK Pierscionek
Scientific Reports 4 (1), 1-8, 2014
Structure–activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1
JE Egleton, CC Thinnes, PT Seden, N Laurieri, SP Lee, KS Hadavizadeh, ...
Bioorganic & medicinal chemistry 22 (11), 3030-3054, 2014
Identification of novel members of the bacterial azoreductase family in Pseudomonas aeruginosa
V Crescente, SM Holland, S Kashyap, E Polycarpou, E Sim, A Ryan
Biochemical Journal 473 (5), 549-558, 2016
Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti‐tubercular agents using a fragment‐based drug design approach
A Ryan, E Polycarpou, NA Lack, D Evangelopoulos, C Sieg, A Halman, ...
British journal of pharmacology 174 (14), 2209-2224, 2017
Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophy
O Eleftheriadou, A Boguslavskyi, MR Longman, J Cowan, A Francois, ...
Basic research in cardiology 112 (4), 37, 2017
The role of apolipoprotein N‐acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target
RAG da Silva, CP Churchward, AV Karlyshev, O Eleftheriadou, ...
British journal of pharmacology 174 (14), 2247-2260, 2017
Purification, quantification, and functional analysis of Complement Factor H
BB Yu, BE Moffatt, M Fedorova, CGS Villiers, JN Arnold, E Du, A Swinkels, ...
The Complement System, 207-223, 2014
Mechanism-based inhibition of HsaD: a C-C bond hydrolase essential for survival of Mycobacterium tuberculosis in macrophage
A Ryan, S Keany, O Eleftheriadou, R Ballet, HY Cheng, E Sim
FEMS microbiology letters 350 (1), 42-47, 2014
Comparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues
T Tsirka, M Konstantopoulou, A Sabbagh, B Crouau-Roy, A Ryan, E Sim, ...
Scientific reports 8 (1), 1-13, 2018
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