| Effect of detergent on “promiscuous” inhibitors AJ Ryan, NM Gray, PN Lowe, C Chung Journal of medicinal chemistry 46 (16), 3448-3451, 2003 | 288 | 2003 |
| Arylamine N‐acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery E Sim, A Abuhammad, A Ryan British Journal of Pharmacology 171 (11), 2705-2725, 2014 | 159 | 2014 |
| Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin AJ Ryan, J Ghuman, PA Zunszain, C Chung, S Curry Journal of Structural Biology 174 (1), 84-91, 2011 | 157 | 2011 |
| Azoreductases in drug metabolism A Ryan British Journal of Pharmacology 174 (14), 2161-2173, 2017 | 75 | 2017 |
| A novel mechanism for azoreduction A Ryan, N Laurieri, CJ Wang, I Westwood, E Lowe, E Sim Acta Crystallographica Section A: Foundations of Crystallography 66 (a1 …, 2010 | 66 | 2010 |
| Improvements in behaviour and physical manifestations in previously untreated adults with phenylketonuria using a phenylalanine‐restricted diet: a national survey S Yannicelli, A Ryan Journal of inherited metabolic disease 18 (2), 131-134, 1995 | 66 | 1995 |
| Identification of NAD (P) H quinone oxidoreductase activity in azoreductases from P. aeruginosa: azoreductases and NAD (P) H quinone oxidoreductases belong to the same FMN … A Ryan, E Kaplan, JC Nebel, E Polycarpou, V Crescente, E Lowe, ... PloS one 9 (6), e98551, 2014 | 60* | 2014 |
| Reaction mechanism of azoreductases suggests convergent evolution with quinone oxidoreductases A Ryan, CJ Wang, N Laurieri, I Westwood, E Sim Protein & cell 1, 780-790, 2010 | 60 | 2010 |
| Activation of nitrofurazone by azoreductases: multiple activities in one enzyme A Ryan, E Kaplan, N Laurieri, E Lowe, E Sim Scientific Reports 1 (1), 63, 2011 | 48 | 2011 |
| Extracorporeal enzyme reactors for depletion of phenylalanine in phenylketonuria CM AMBRUS, S ANTHONE, C HORVATH, K KALGHATGI, AS LELE, ... Annals of internal medicine 106 (4), 531-537, 1987 | 47 | 1987 |
| Crystallographic analysis reveals the structural basis of the high-affinity binding of iophenoxic acid to human serum albumin AJ Ryan, C Chung, S Curry BMC structural biology 11, 1-7, 2011 | 40 | 2011 |
| Primary sequence contribution to the optical function of the eye lens K Mahendiran, C Elie, JC Nebel, A Ryan, BK Pierscionek Scientific Reports 4 (1), 5195, 2014 | 35 | 2014 |
| Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide CJ Wang, N Laurieri, A Abuhammad, E Lowe, I Westwood, A Ryan, E Sim Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 34 | 2010 |
| Structure–activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1 JE Egleton, CC Thinnes, PT Seden, N Laurieri, SP Lee, KS Hadavizadeh, ... Bioorganic & medicinal chemistry 22 (11), 3030-3054, 2014 | 27 | 2014 |
| Anakinra for palmoplantar pustulosis: results from a randomized, double‐blind, multicentre, two‐staged, adaptive placebo‐controlled trial (APRICOT) S Cro, VR Cornelius, AE Pink, R Wilson, A Pushpa‐Rajah, P Patel, ... British Journal of Dermatology 186 (2), 245-256, 2022 | 24 | 2022 |
| Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti‐tubercular agents using a fragment‐based drug design approach A Ryan, E Polycarpou, NA Lack, D Evangelopoulos, C Sieg, A Halman, ... British journal of pharmacology 174 (14), 2209-2224, 2017 | 22 | 2017 |
| Identification of novel members of the bacterial azoreductase family in Pseudomonas aeruginosa V Crescente, SM Holland, S Kashyap, E Polycarpou, E Sim, A Ryan Biochemical Journal 473 (5), 549-558, 2016 | 21 | 2016 |
| Comparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues T Tsirka, M Konstantopoulou, A Sabbagh, B Crouau-Roy, A Ryan, E Sim, ... Scientific reports 8 (1), 9759, 2018 | 18 | 2018 |
| The role of apolipoprotein N‐acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target RAG Da Silva, CP Churchward, AV Karlyshev, O Eleftheriadou, ... British Journal of Pharmacology 174 (14), 2247-2260, 2017 | 16 | 2017 |
| Potential use of the maillard reaction for pharmaceutical applications: Gastric and intestinal controlled release alginate-albumin beads M Khoder, HK Gbormoi Sr, A Ryan, A Karam, RG Alany Pharmaceutics 11 (2), 83, 2019 | 15 | 2019 |
