Ran Brosh
Ran Brosh
NYU Langone
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When mutants gain new powers: news from the mutant p53 field
R Brosh, V Rotter
Nature reviews cancer 9 (10), 701-713, 2009
Mutations in the p53 tumor suppressor gene: important milestones at the various steps of tumorigenesis
N Rivlin, R Brosh, M Oren, V Rotter
Genes & cancer 2 (4), 466-474, 2011
Epigenetic polymorphism and the stochastic formation of differentially methylated regions in normal and cancerous tissues
G Landan, NM Cohen, Z Mukamel, A Bar, A Molchadsky, R Brosh, ...
Nature genetics 44 (11), 1207-1214, 2012
p53 is balancing development, differentiation and de-differentiation to assure cancer prevention
A Molchadsky, N Rivlin, R Brosh, V Rotter, R Sarig
Carcinogenesis 31 (9), 1501-1508, 2010
p53-dependent down-regulation of telomerase is mediated by p21waf1
I Shats, M Milyavsky, X Tang, P Stambolsky, N Erez, R Brosh, I Kogan, ...
Journal of Biological Chemistry 279 (49), 50976-50985, 2004
p53‐repressed miRNAs are involved with E2F in a feed‐forward loop promoting proliferation
R Brosh, R Shalgi, A Liran, G Landan, K Korotayev, GH Nguyen, E Enerly, ...
Molecular systems biology 4 (1), 229, 2008
Mutant p53 facilitates somatic cell reprogramming and augments the malignant potential of reprogrammed cells
R Sarig, N Rivlin, R Brosh, C Bornstein, I Kamer, O Ezra, A Molchadsky, ...
Journal of Experimental Medicine 207 (10), 2127-2140, 2010
TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model
O Leshem, S Madar, I Kogan-Sakin, I Kamer, I Goldstein, R Brosh, ...
PloS one 6 (7), e21650, 2011
Modulated expression of WFDC1 during carcinogenesis and cellular senescence
S Madar, R Brosh, Y Buganim, O Ezra, I Goldstein, H Solomon, I Kogan, ...
Carcinogenesis 30 (1), 20-27, 2009
Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature
H Solomon, Y Buganim, I Kogan-Sakin, L Pomeraniec, Y Assia, S Madar, ...
Journal of cell science 125 (13), 3144-3152, 2012
p53 Regulates the Ras circuit to inhibit the expression of a cancer-related gene signature by various molecular pathways
Y Buganim, H Solomon, Y Rais, D Kistner, I Nachmany, M Brait, S Madar, ...
Cancer research 70 (6), 2274-2284, 2010
Prostate stromal cells produce CXCL-1, CXCL-2, CXCL-3 and IL-8 in response to epithelia-secreted IL-1
I Kogan-Sakin, M Cohen, N Paland, S Madar, H Solomon, A Molchadsky, ...
Carcinogenesis 30 (4), 698-705, 2009
Wide-scale analysis of human functional transcription factor binding reveals a strong bias towards the transcription start site
Y Tabach, R Brosh, Y Buganim, A Reiner, O Zuk, A Yitzhaky, M Koudritsky, ...
PloS one 2 (8), e807, 2007
The promoters of human cell cycle genes integrate signals from two tumor suppressive pathways during cellular transformation
Y Tabach, M Milyavsky, I Shats, R Brosh, O Zuk, A Yitzhaky, R Mantovani, ...
Molecular systems biology 1 (1), 2005.0022, 2005
Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect
M Milyavsky, I Shats, A Cholostoy, R Brosh, Y Buganim, L Weisz, I Kogan, ...
Cancer cell 11 (2), 133-146, 2007
A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons
A Sybirna, WWC Tang, M Pierson Smela, S Dietmann, WH Gruhn, ...
Nature communications 11 (1), 1282, 2020
A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype
Y Buganim, I Goldstein, D Lipson, M Milyavsky, S Polak-Charcon, ...
PloS one 5 (3), e9657, 2010
Structural Basis of Restoring Sequence-Specific DNA Binding and Transactivation to Mutant p53 by Suppressor Mutations☆
ZS O Suad, H Rozenberg, R Brosh, Y Diskin-Posner, N Kessler, L.J.W Shimon, F ...
J. Mol. Biol 385, 249-265, 2009
Coupling transcriptional and post-transcriptional miRNA regulation in the control of cell fate
R Shalgi, R Brosh, M Oren, Y Pilpel, V Rotter
Aging (Albany NY) 1 (9), 762, 2009
Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm
A Waghray, N Saiz, AD Jayaprakash, AG Freire, D Papatsenko, ...
stem Cell Reports, 2015
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