| Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations V Sequeira, PJM Wijnker, LLAM Nijenkamp, DWD Kuster, A Najafi, ... Circulation research 112 (11), 1491-1505, 2013 | 217 | 2013 |
| Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations ER Witjas-Paalberends, A Güçlü, T Germans, P Knaapen, HJ Harms, ... Cardiovascular research 103 (2), 248-257, 2014 | 122 | 2014 |
| Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy ER Witjas-Paalberends, N Piroddi, K Stam, SJ Van Dijk, VS Oliviera, ... Cardiovascular research 99 (3), 432-441, 2013 | 119 | 2013 |
| Faster cross‐bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation ER Witjas‐Paalberends, C Ferrara, B Scellini, N Piroddi, J Montag, C Tesi, ... The Journal of physiology 592 (15), 3257-3272, 2014 | 89 | 2014 |
| Familial hypertrophic cardiomyopathy: functional effects of myosin mutation R723G in cardiomyocytes T Kraft, ER Witjas-Paalberends, NM Boontje, S Tripathi, A Brandis, ... Journal of molecular and cellular cardiology 57, 13-22, 2013 | 66 | 2013 |
| GSK3β phosphorylates newly identified site in the proline-alanine–rich region of cardiac myosin–binding protein C and alters cross-bridge cycling kinetics in human DWD Kuster, V Sequeira, A Najafi, NM Boontje, PJM Wijnker, ... Circulation research 112 (4), 633-639, 2013 | 63 | 2013 |
| Challenges and best practices for big data-driven healthcare innovations conducted by profit–non-profit partnerships–a quantitative prioritization ER Witjas-Paalberends, LPM van Laarhoven, LHM van de Burgwal, ... International Journal of Healthcare Management 11 (3), 171-181, 2018 | 43 | 2018 |
| Cardiac myosin-binding protein C: hypertrophic cardiomyopathy mutations and structure–function relationships V Sequeira, ER Witjas-Paalberends, DWD Kuster, J van der Velden Pflügers Archiv-European Journal of Physiology 466, 201-206, 2014 | 32 | 2014 |
| The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM N Piroddi, ER Witjas-Paalberends, C Ferrara, C Ferrantini, G Vitale, ... Journal of General Physiology 151 (1), 18-29, 2019 | 26 | 2019 |
| Phosphorylation of protein kinase C sites Ser42/44 decreases Ca2+-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human … PJM Wijnker, V Sequeira, ER Witjas-Paalberends, DB Foster, ... Archives of biochemistry and biophysics 554, 11-21, 2014 | 20 | 2014 |
| ENerGetIcs in hypertrophic cardiomyopathy: traNslation between MRI, PET and cardiac myofilament function (ENGINE study) A Güçlü, T Germans, ER Witjas-Paalberends, GJM Stienen, WP Brouwer, ... Netherlands Heart Journal 21, 567-571, 2013 | 15 | 2013 |
| Increased energy utilization for force generation in human familial hypertrophic cardiomyopathy caused by sarcomere gene mutations J Van Der Velden, ER Witjas-Paalberends, GJM Stienen, ... European Heart Journal 34 (suppl_1), P4192, 2013 | 7 | 2013 |
| The HCM-associated cardiac troponin T mutation K280N increases the energetic cost of tension generation in human cardiac myofibrils C Ferrara, ER Witjas-Paalberends, N Piroddi, B Scellini, C Tesi, ... Biophysical Journal 104 (2), 187a, 2013 | 7 | 2013 |
| A novel homozygous HCM mutation in cardiac troponin T primarily alters cross-bridge kinetics and the energy cost of tension generation in human cardiac muscle N Piroddi, E Witjas-Paalberends, C Ferrara, C Ferrantini, G Vitale, ... J Gen Physiol 151 (1), 18-29, 2019 | 2 | 2019 |
| A novel HCM mutation in cardiac troponin T primarily alters cross-bridge kinetics and increases the energetic cost of tension generation in human cardiac tissue C Ferrara, ER Witjas-Paalberends, N Piroddi, B Scellini, C Ferrantini, ... | 1 | 2023 |
| Association between contractile dysfunction of the sarcomere and impaired regional systolic strain in hypertrophic cardiomyopathy PA Vriesendorp, ER Witjas-Paalberends, A Schinkel, V Sequeira, ... Journal of the American College of Cardiology 63 (12S), A727-A727, 2014 | 1 | 2014 |
| Actin carbonylation is higher in human hypertrophic cardiomyopathy due to MYH7 mutations R Witjas-Paalberends, M Canton, M Michels, C Ho, C Poggesi, F di Lisa, ... Biophysical Journal 106 (2), 778a-779a, 2014 | 1 | 2014 |
| Positive correlation between contractile dysfunction of the sarcomere and impaired regional systolic strain in hypertrophic cardiomyopathy. PA Vriesendop, ER Witjas-Paalberends, AFL Schinkel, L Nijenkamp, ... Improving Outcomes in Hypertrophic Cardiomyopathy, 243, 2016 | | 2016 |
| Energy deficiency as target of treatment in hypertrophic cardiomyopathy R Witjas-Paalberends, A Guclu, M Michels, J van der Velden ACTA PHYSIOLOGICA 213, 14-14, 2015 | | 2015 |
| Gene-specific increase in energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations: in vitro and in vivo assessment of cardiac efficiency A Guclu, ER Witjas-Paalberends, T Germans, P Knaapen, HJ Harms, ... EUROPEAN HEART JOURNAL 35, 24-24, 2014 | | 2014 |
