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Yen-Der Li
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Coronavirus vaccine development: from SARS and MERS to COVID-19
YD Li, WY Chi, JH Su, L Ferrall, CF Hung, TC Wu
Journal of biomedical science 27, 1-23, 2020
5162020
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K
M Słabicki, Z Kozicka, G Petzold, YD Li, M Manojkumar, RD Bunker, ...
Nature 585 (7824), 293-297, 2020
2502020
COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection
WY Chi, YD Li, HC Huang, TEH Chan, SY Chow, JH Su, L Ferrall, ...
Journal of biomedical science 29 (1), 82, 2022
1172022
Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment
SWD Tsen, N Donthi, V La, WH Hsieh, YD Li, J Knoff, A Chen, TC Wu, ...
Journal of biomedical optics 20 (5), 051008-051008, 2015
272015
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders
YD Li, MW Ma, MM Hassan, M Hunkeler, M Teng, K Puvar, R Lumpkin, ...
BioRxiv, 2023
222023
Development of PDE6D and CK1α degraders through chemical derivatization of FPFT-2216
M Teng, W Lu, KA Donovan, J Sun, NM Krupnick, RP Nowak, YD Li, ...
Journal of medicinal chemistry 65 (1), 747-756, 2021
212021
PD-1 blockade synergizes with intratumoral vaccination of a therapeutic HPV protein vaccine and elicits regression of tumor in a preclinical model
S Peng, M Tan, YD Li, MA Cheng, E Farmer, L Ferrall, S Gaillard, ...
Cancer Immunology, Immunotherapy 70, 1049-1062, 2021
192021
How SARS-CoV-2 transformed the clinical laboratory: challenges and lessons learned
JM Tsai, NV Tolan, AK Petrides, S Kanjilal, M Brigl, NI Lindeman, YD Li, ...
The journal of applied laboratory medicine 6 (5), 1338-1354, 2021
172021
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability
JM Tsai, JD Aguirre, YD Li, J Brown, V Focht, L Kater, G Kempf, ...
Molecular Cell 83 (15), 2753-2767. e10, 2023
132023
Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry
RC Sarott, I You, YD Li, ST Toenjes, KA Donovan, P Seo, M Ordonez, ...
Journal of the American Chemical Society 145 (40), 21937-21944, 2023
62023
Induced protein degradation for therapeutics: past, present, and future
H Yoon, JC Rutter, YD Li, BL Ebert
The Journal of Clinical Investigation 134 (1), 2024
32024
Exploration of the Tunability of BRD4 Degradation by DCAF16 Trans-labelling Covalent Glues
MM Hassan, YD Li, MW Ma, M Teng, WS Byun, K Puvar, R Lumpkin, ...
BioRxiv, 2023
32023
Outlier expression of isoforms by targeted or total RNA sequencing identifies clinically significant genomic variants in hematolymphoid tumors
HK Tsai, T Gogakos, V Lip, JM Tsai, YD Li, AS Fisch, J Weiss, W Yang, ...
The Journal of Molecular Diagnostics 25 (9), 665-681, 2023
32023
Integration of Genomic Sequencing Drives Therapeutic Targeting of PDGFRA in T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
J Paolino, B Dimitrov, B Apsel Winger, A Sandoval-Perez, AV Rangarajan, ...
Clinical Cancer Research 29 (22), 4613-4626, 2023
12023
The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein
C Zou, H Yoon, PMC Park, JJ Patten, J Pellman, J Carreiro, JM Tsai, ...
Iscience 26 (5), 2023
12023
Outlier expression of isoforms by targeted RNA sequencing as clinical markers of genomic variants in B lymphoblastic leukemia and other tumor types
HK Tsai, T Gogakos, V Lip, J Tsai, YD Li, A Fisch, J Weiss, L Grimmett, ...
medRxiv, 2022.07. 29.22278149, 2022
12022
Template-assisted covalent modification of DCAF16 enables BRD4 molecular glue degraders
YD Li, MW Ma, MM Hassan, K Puvar, M Teng, B Sandoval, R Lumpkin, ...
Cancer Research 83 (7_Supplement), 3424-3424, 2023
2023
Discovery of Novel Molecular Glues and Targeted Protein Degradation Mechanisms for Cancer Therapeutics
YD Li
Harvard University, 2023
2023
UBR5 Is a Hect E3 Ubiquitin Ligase That Regulates Chromatin Bound Nuclear Hormone Receptor Stability
JM Tsai, JD Aguirre, J Brown, V Focht, YD Li, G Kempf, L Kater, P Galli, ...
Blood 140 (Supplement 1), 2968-2969, 2022
2022
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Articles 1–19