David Broadhurst
David Broadhurst
Professor, Biosystems Data Science, School of Science, Edith Cowan University
Verified email at - Homepage
Cited by
Cited by
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
WB Dunn, D Broadhurst, P Begley, E Zelena, S Francis-McIntyre, ...
Nature protocols 6 (7), 1060-1083, 2011
A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations
LM Raamsdonk, B Teusink, D Broadhurst, N Zhang, A Hayes, MC Walsh, ...
Nature biotechnology 19 (1), 45-50, 2001
MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis.
J Xia, R Mandal, IV Sinelnikov, D Broadhurst, DS Wishart
Nucleic Acids Res, 2012
Translational biomarker discovery in clinical metabolomics: an introductory tutorial
J Xia, DI Broadhurst, M Wilson, DS Wishart
Metabolomics 9 (2), 280-299, 2013
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
WB Dunn, DI Broadhurst, HJ Atherton, R Goodacre, JL Griffin
Chemical society reviews 40 (1), 387-426, 2011
Statistical strategies for avoiding false discoveries in metabolomics and related experiments
DI Broadhurst, DB Kell
Metabolomics 2, 171-196, 2006
Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies
D Broadhurst, R Goodacre, SN Reinke, J Kuligowski, ID Wilson, ...
Metabolomics 14, 1-17, 2018
High-throughput classification of yeast mutants for functional genomics using metabolic footprinting
J Allen, HM Davey, D Broadhurst, JK Heald, JJ Rowland, SG Oliver, ...
Nature biotechnology 21 (6), 692-696, 2003
Development of a robust and repeatable UPLC− MS method for the long-term metabolomic study of human serum
E Zelena, WB Dunn, D Broadhurst, S Francis-McIntyre, KM Carroll, ...
Analytical chemistry 81 (4), 1357-1364, 2009
Metabolomics enables precision medicine:“a white paper, community perspective”
RD Beger, W Dunn, MA Schmidt, SS Gross, JA Kirwan, M Cascante, ...
Metabolomics 12, 1-15, 2016
Proposed minimum reporting standards for data analysis in metabolomics
R Goodacre, D Broadhurst, AK Smilde, BS Kristal, JD Baker, R Beger, ...
Metabolomics 3, 231-241, 2007
The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans
WB Dunn, ID Wilson, AW Nicholls, D Broadhurst
Bioanalysis 4 (18), 2249-2264, 2012
Rapid and quantitative detection of the microbial spoilage of meat by Fourier transform infrared spectroscopy and machine learning
DI Ellis, D Broadhurst, DB Kell, JJ Rowland, R Goodacre
Applied and environmental microbiology 68 (6), 2822-2828, 2002
Global Metabolic Profiling of Escherichia coli Cultures:  an Evaluation of Methods for Quenching and Extraction of Intracellular Metabolites
CL Winder, WB Dunn, S Schuler, D Broadhurst, R Jarvis, GM Stephens, ...
Analytical Chemistry 80 (8), 2939-2948, 2008
Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers
LC Kenny, DI Broadhurst, W Dunn, M Brown, RA North, L McCowan, ...
Hypertension 56 (4), 741-749, 2010
Genetic algorithms as a method for variable selection in multiple linear regression and partial least squares regression, with applications to pyrolysis mass spectrometry
D Broadhurst, R Goodacre, A Jones, JJ Rowland, DB Kell
Analytica Chimica Acta 348 (1-3), 71-86, 1997
Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics
M Brown, WB Dunn, P Dobson, Y Patel, CL Winder, S Francis-McIntyre, ...
Analyst 134 (7), 1322-1332, 2009
Metabolic fingerprinting of salt-stressed tomatoes
HE Johnson, D Broadhurst, R Goodacre, AR Smith
Phytochemistry 62 (6), 919-928, 2003
Growth control of the eukaryote cell: a systems biology study in yeast
JI Castrillo, LA Zeef, DC Hoyle, N Zhang, A Hayes, DCJ Gardner, ...
Journal of biology 6, 1-25, 2007
Molecular phenotyping of a UK population: defining the human serum metabolome
WB Dunn, W Lin, D Broadhurst, P Begley, M Brown, E Zelena, ...
Metabolomics, 1-18, 2014
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