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Ronald M. Paranal, MD
Ronald M. Paranal, MD
Hematology-Oncology Fellow, University of Washington/Fred Hutchinson Cancer Research Center
Verified email at uw.edu - Homepage
Title
Cited by
Cited by
Year
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
JE Delmore, GC Issa, ME Lemieux, PB Rahl, J Shi, HM Jacobs, E Kastritis, ...
Cell 146 (6), 904-917, 2011
30682011
Transcriptional amplification in tumor cells with elevated c-Myc
CY Lin, J Lovén, PB Rahl, RM Paranal, CB Burge, JE Bradner, TI Lee, ...
Cell 151 (1), 56-67, 2012
16072012
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis
JD Brown, CY Lin, Q Duan, G Griffin, AJ Federation, RM Paranal, S Bair, ...
Molecular cell 56 (2), 219-231, 2014
5912014
BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
CJ Ott, N Kopp, L Bird, RM Paranal, J Qi, T Bowman, SJ Rodig, AL Kung, ...
Blood, The Journal of the American Society of Hematology 120 (14), 2843-2852, 2012
4622012
Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition
O Weigert, AA Lane, L Bird, N Kopp, B Chapuy, D van Bodegom, ...
Journal of experimental medicine 209 (2), 259-273, 2012
1702012
Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma
T Hideshima, J Qi, RM Paranal, W Tang, E Greenberg, N West, ...
Proceedings of the National Academy of Sciences 113 (46), 13162-13167, 2016
1242016
Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation
SM Frumm, ZP Fan, KN Ross, JR Duvall, S Gupta, L VerPlank, BC Suh, ...
Chemistry & biology 20 (5), 713-725, 2013
1062013
Synthesis and biological evaluation of JAHAs: ferrocene-based histone deacetylase inhibitors
J Spencer, J Amin, M Wang, G Packham, SSS Alwi, GJ Tizzard, SJ Coles, ...
ACS medicinal chemistry letters 2 (5), 358-362, 2011
1002011
Development of a potent and selective HDAC8 inhibitor
OJ Ingham, RM Paranal, WB Smith, RA Escobar, H Yueh, T Snyder, ...
ACS medicinal chemistry letters 7 (10), 929-932, 2016
722016
Click JAHAs: conformationally restricted ferrocene-based histone deacetylase inhibitors
J Spencer, J Amin, R Boddiboyena, G Packham, BE Cavell, SSS Alwi, ...
MedChemComm 3 (1), 61-64, 2012
502012
C-terminal binding protein-2 regulates response of epithelial ovarian cancer cells to histone deacetylase inhibitors
L Barroilhet, J Yang, K Hasselblatt, RM Paranal, SK Ng, JA Rauh-Hain, ...
Oncogene 32 (33), 3896-3903, 2013
492013
Synthesis and HDAC inhibitory activity of isosteric thiazoline-oxazole largazole analogs
JM Guerra-Bubb, AA Bowers, WB Smith, R Paranal, G Estiu, O Wiest, ...
Bioorganic & medicinal chemistry letters 23 (21), 6025-6028, 2013
372013
Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors
H Patel, I Chuckowree, P Coxhead, M Guille, M Wang, A Zuckermann, ...
MedChemComm 5 (12), 1829-1833, 2014
262014
The oral manifestations of syphilitic disease: a case report
KL Streight, RM Paranal, DM Musher
Journal of medical case reports 13, 1-3, 2019
242019
Syntheses and discovery of a novel class of cinnamic hydroxamates as histone deacetylase inhibitors by multimodality molecular imaging in living subjects
CT Chan, J Qi, W Smith, R Paranol, R Mazitschek, N West, R Reeves, ...
Cancer research 74 (24), 7475-7486, 2014
122014
Impact of luteinizing hormone suppression on hematopoietic recovery after intensive chemotherapy in patients with leukemia
I Abou Dalle, R Paranal, J Zarka, S Paul, K Sasaki, W Li, J Ning, NJ Short, ...
Haematologica 106 (4), 1097, 2021
102021
A cyclodextrin-capped histone deacetylase inhibitor
J Amin, A Puglisi, J Clarke, J Milton, M Wang, RM Paranal, JE Bradner, ...
Bioorganic & medicinal chemistry letters 23 (11), 3346-3348, 2013
102013
Epigenomic analysis of formalin-fixed paraffin-embedded samples by CUT&Tag
S Henikoff, JG Henikoff, K Ahmad, RM Paranal, DH Janssens, ZR Russell, ...
Nature Communications 14 (1), 5930, 2023
22023
Genetic Cardiomyopathies
RM Paranal, P Teekakirikul, CY Ho, D Fatkin, CE Seidman
Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics …, 2020
22020
BET Bromodomain Inhibition Targets Both c-Myc and IL7R in Acute Lymphoblastic Leukemia
N Kopp, CJ Ott, L Bird, R Paranal, J Qi, T Bowman, SJ Rodig, AL Kung, ...
Blood 120 (21), 672, 2012
22012
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