Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart KA Cieslik, GE Taffet, S Carlson, J Hermosillo, JA Trial, ML Entman Journal of molecular and cellular cardiology 50 (1), 248-256, 2011 | 154 | 2011 |
Salicylate suppresses macrophage nitric-oxide synthase-2 and cyclo-oxygenase-2 expression by inhibiting CCAAT/enhancer-binding protein-β binding via a common signaling pathway K Cieslik, Y Zhu, KK Wu Journal of Biological Chemistry 277 (51), 49304-49310, 2002 | 103 | 2002 |
Transcriptional regulation of endothelial nitric-oxide synthase by lysophosphatidylcholine K Cieslik, A Zembowicz, JL Tang, KK Wu Journal of Biological Chemistry 273 (24), 14885-14890, 1998 | 101 | 1998 |
Transcriptional control of COX-2 via C/EBPβ KK Wu, JY Liou, K Cieslik Arteriosclerosis, thrombosis, and vascular biology 25 (4), 679-685, 2005 | 90 | 2005 |
Up-regulation of endothelial nitric-oxide synthase promoter by the phosphatidylinositol 3-kinase γ/Janus kinase 2/MEK-1-dependent pathway K Cieslik, CS Abrams, KK Wu Journal of Biological Chemistry 276 (2), 1211-1219, 2001 | 79 | 2001 |
Adverse fibrosis in the aging heart depends on signaling between myeloid and mesenchymal cells; role of inflammatory fibroblasts KA Cieslik, JA Trial, JR Crawford, GE Taffet, ML Entman Journal of molecular and cellular cardiology 70, 56-63, 2014 | 75 | 2014 |
Protein kinase Cδ mediates platelet-induced breast cancer cell invasion D Alonso-Escolano, C Medina, K Cieslik, A Radomski, P Jurasz, ... Journal of Pharmacology and Experimental Therapeutics 318 (1), 373-380, 2006 | 63 | 2006 |
Transcriptional regulation of endothelial nitric-oxide synthase by an interaction between casein kinase 2 and protein phosphatase 2A K Cieslik, CM Lee, JL Tang, KK Wu Journal of Biological Chemistry 274 (49), 34669-34675, 1999 | 62 | 1999 |
AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction KA Cieslik, GE Taffet, JR Crawford, JA Trial, PM Osuna, ML Entman Journal of molecular and cellular cardiology 63, 26-36, 2013 | 61 | 2013 |
Defective myofibroblast formation from mesenchymal stem cells in the aging murine heart: rescue by activation of the AMPK pathway KA Cieslik, JA Trial, ML Entman The American journal of pathology 179 (4), 1792-1806, 2011 | 60 | 2011 |
Mechanosensing dysregulation in the fibroblast: a hallmark of the aging heart A Angelini, JA Trial, J Ortiz-Urbina, KA Cieslik Ageing research reviews 63, 101150, 2020 | 59 | 2020 |
Peroxisome proliferator-activated receptor-δ upregulates 14-3-3ε in human endothelial cells via CCAAT/enhancer binding protein-β L Brunelli, KA Cieslik, JL Alcorn, M Vatta, A Baldini Circulation research 100 (5), e59-e71, 2007 | 59 | 2007 |
Origin of developmental precursors dictates the pathophysiologic role of cardiac fibroblasts JR Crawford, SB Haudek, KA Cieslik, JA Trial, ML Entman Journal of cardiovascular translational research 5, 749-759, 2012 | 58 | 2012 |
14-3-3ε plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle Y Kosaka, KA Cieslik, L Li, G Lezin, CT Maguire, Y Saijoh, K Toyo-oka, ... Molecular and Cellular Biology, 2012 | 54 | 2012 |
Mesenchymal stem cell-derived inflammatory fibroblasts mediate interstitial fibrosis in the aging heart JA Trial, ML Entman, KA Cieslik Journal of molecular and cellular cardiology 91, 28-34, 2016 | 52 | 2016 |
Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels KA Cieslik, JA Trial, S Carlson, GE Taffet, ML Entman The FASEB Journal 27 (4), 1761, 2013 | 43 | 2013 |
Th1/M1 conversion to th2/m2 responses in models of inflammation lacking cell death stimulates maturation of monocyte precursors to fibroblasts JA Trial, KA Cieslik, SB Haudek, C Duerrschmid, ML Entman Frontiers in immunology 4, 54076, 2013 | 41 | 2013 |
Changes in cardiac resident fibroblast physiology and phenotype in aging JA Trial, KA Cieslik American Journal of Physiology-Heart and Circulatory Physiology 315 (4 …, 2018 | 38 | 2018 |
Improved cardiovascular function in old mice after N-acetyl cysteine and glycine supplemented diet: inflammation and mitochondrial factors KA Cieslik, RV Sekhar, A Granillo, A Reddy, G Medrano, CP Heredia, ... The Journals of Gerontology: Series A 73 (9), 1167-1177, 2018 | 37 | 2018 |
Mesenchymal stem cell-derived inflammatory fibroblasts promote monocyte transition into myeloid fibroblasts via an IL-6-dependent mechanism in the aging mouse heart KA Cieslik, JA Trial, ML Entman The FASEB Journal 29 (8), 3160, 2015 | 34 | 2015 |