Yu (Brandon) Xia

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Mark GersteinProfessor of Biomedical Informatics, Yale UniversityVerified email at yale.edu
Haiyuan YuProfessor, Cornell UniversityVerified email at cornell.edu
Eric Alan FranzosaSenior Research Scientist / Harvard T. H. Chan School of Public HealthVerified email at hsph.harvard.edu
Michael LevittStructural Biology, Stanford UniversityVerified email at stanford.edu
Enoch S. HuangPfizer IncVerified email at pfizer.com
Ram SamudralaProfessor and Chief, Division of Bioinformatics, University at BuffaloVerified email at compbio.org
Shang-Hua TengUniversity Professor of Computer Science and Math, USCVerified email at usc.edu
Marc VidalProfessor of Genetics, Harvard Medical SchoolVerified email at dfci.harvard.edu
Sara GaramszegiBioinformatics Program, Boston UniversityVerified email at bu.edu
Philip M. KimProfessor, University of TorontoVerified email at kimlab.org
Nicholas LuscombeOkinawa Institute of Science and Technology Graduate UniversityVerified email at oist.jp
Nicolas BertinGenome Institute of SingaporeVerified email at gis.a-star.edu.sg
Xiaowei zhuStanford UniversityVerified email at stanford.edu
Amie J. McClellanBennington College, Stanford University, University of PIttsburghVerified email at bennington.edu
Jasmin Coulombe-HuntingtonFaculty Lecturer, Department of Bioengineering, McGill UniversityVerified email at mcgill.ca
Donald EngelmanProfessor of Molecular Biophysics and Biochemistry, YaleVerified email at yale.edu
Mohamed GhadieAffiliate Scientist, Princess Margaret Cancer Research CentreVerified email at uhnresearch.ca
Heiko RöglinProfessor of Computer Science, University of BonnVerified email at cs.uni-bonn.de
Maria-Florina BalcanProfessor, School of Computer Science, Carnegie Mellon UniversityVerified email at cs.cmu.edu
Amine KamenNational research Council and McGill UniversityVerified email at mcgill.ca

Yu (Brandon) Xia

Other namesYu Xia

Professor of Bioengineering, McGill University

Verified email at mcgill.ca - Homepage

Computational Biology Structural Bioinformatics Network Biology Evolution


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A proteome-scale map of the human interactome network T Rolland, M Taşan, B Charloteaux, SJ Pevzner, Q Zhong, N Sahni, S Yi, ... Cell 159 (5), 1212-1226, 2014	1486	2014
A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature, 1-7, 2020	1022	2020
Annotation transfer between genomes: protein–protein interologs and protein–DNA regulogs H Yu, NM Luscombe, HX Lu, X Zhu, Y Xia, JDJ Han, N Bertin, S Chung, ... Genome research 14 (6), 1107-1118, 2004	689	2004
Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches AJ McClellan, Y Xia, AM Deutschbauer, RW Davis, M Gerstein, J Frydman Cell 131 (1), 121-135, 2007	585	2007
Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ... Cell 161 (3), 647-660, 2015	584	2015
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing X Yang, J Coulombe-Huntington, S Kang, GM Sheynkman, T Hao, ... Cell 164 (4), 805-817, 2016	571	2016
Relating three-dimensional structures to protein networks provides evolutionary insights PM Kim, LJ Lu, Y Xia, MB Gerstein Science 314 (5807), 1938, 2006	557	2006
Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly made proteins with complex topologies AY Yam, Y Xia, HTJ Lin, A Burlingame, M Gerstein, J Frydman Nature structural & molecular biology 15 (12), 1255-1262, 2008	446	2008
Assessing the limits of genomic data integration for predicting protein networks LJ Lu, Y Xia, A Paccanaro, H Yu, M Gerstein Genome research 15 (7), 945-953, 2005	268	2005
The role of disorder in interaction networks: a structural analysis PM Kim, A Sboner, Y Xia, M Gerstein Molecular Systems Biology 4 (1), 179, 2008	265	2008
Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network B Linghu, ES Snitkin, Z Hu, Y Xia, C DeLisi Genome Biol 10 (9), R91, 2009	264	2009
Ab initio construction of protein tertiary structures using a hierarchical approach Y Xia, ES Huang, M Levitt, R Samudrala Journal of molecular biology 300 (1), 171-185, 2000	220	2000
Structural determinants of protein evolution are context-sensitive at the residue level EA Franzosa, Y Xia Molecular biology and evolution 26 (10), 2387-2395, 2009	199	2009
Analyzing cellular biochemistry in terms of molecular networks Y Xia, H Yu, R Jansen, M Seringhaus, S Baxter, D Greenbaum, H Zhao, ... Annual review of biochemistry 73 (1), 1051-1087, 2004	173	2004
Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocation D Huber, D Boyd, Y Xia, MH Olma, M Gerstein, J Beckwith Journal of bacteriology 187 (9), 2983-2991, 2005	172	2005
Ab initio protein structure prediction using a combined hierarchical approach R Samudrala, Y Xia, E Huang, M Levitt Proteins: Structure, Function, and Bioinformatics 37 (S3), 194-198, 1999	150	1999
Structural principles within the human-virus protein-protein interaction network EA Franzosa, Y Xia Proceedings of the National Academy of Sciences 108 (26), 10538-10543, 2011	148	2011
A proteome-wide fission yeast interactome reveals network evolution principles from yeasts to human TV Vo, J Das, MJ Meyer, NA Cordero, N Akturk, X Wei, BJ Fair, ... Cell 164 (1), 310-323, 2016	122	2016
Simulating protein evolution in sequence and structure space Y Xia, M Levitt Current opinion in structural biology 14 (2), 202-207, 2004	114	2004
A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome T Bertomeu, J Coulombe-Huntington, A Chatr-aryamontri, KG Bourdages, ... Molecular and cellular biology 38 (1), e00302-17, 2018	98	2018

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