Follow
Cyrille C. Thinnes
Cyrille C. Thinnes
Research Fellow, University of Galway
Verified email at universityofgalway.ie - Homepage
Title
Cited by
Cited by
Year
Targeting histone lysine demethylases—progress, challenges, and the future
CC Thinnes, KS England, A Kawamura, R Chowdhury, CJ Schofield, ...
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (12 …, 2014
2212014
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
TL Yeh, TM Leissing, MI Abboud, CC Thinnes, O Atasoylu, JP Holt-Martyn, ...
Chemical science 8 (11), 7651-7668, 2017
2202017
Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions
F Baldini, J Hertel, E Sandt, CC Thinnes, L Neuberger-Castillo, L Pavelka, ...
BMC biology 18, 1-21, 2020
2052020
5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ...
Chemical science 4 (8), 3110-3117, 2013
1802013
Integrated analyses of microbiome and longitudinal metabolome data reveal microbial-host interactions on sulfur metabolism in Parkinson’s disease
J Hertel, AC Harms, A Heinken, F Baldini, CC Thinnes, E Glaab, ...
Cell reports 29 (7), 1767-1777. e8, 2019
1412019
Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models
SS Karuppagounder, I Alim, SJ Khim, MW Bourassa, SF Sleiman, R John, ...
Science translational medicine 8 (328), 328ra29-328ra29, 2016
1352016
Glucose metabolism and oxygen availability govern reactivation of the latent human retrovirus HTLV-1
A Kulkarni, M Mateus, CC Thinnes, JS McCullagh, CJ Schofield, ...
Cell chemical biology 24 (11), 1377-1387. e3, 2017
642017
Genome-scale metabolic modeling of the human microbiome in the era of personalized medicine
A Heinken, A Basile, J Hertel, C Thinnes, I Thiele
Annual review of microbiology 75 (1), 199-222, 2021
502021
Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases
CC Thinnes, A Tumber, C Yapp, G Scozzafava, T Yeh, MC Chan, TA Tran, ...
Chemical communications 51 (84), 15458-15461, 2015
492015
Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio-and stereoselectivity of prolyl hydroxylases
S Horita, JS Scotti, C Thinnes, YS Mottaghi-Taromsari, A Thalhammer, ...
Structure 23 (4), 639-652, 2015
412015
Structure–activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1
JE Egleton, CC Thinnes, PT Seden, N Laurieri, SP Lee, KS Hadavizadeh, ...
Bioorganic & medicinal chemistry 22 (11), 3030-3054, 2014
282014
Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia …
S Kiriakidis, SS Hoer, N Burrows, G Biddlecome, MN Khan, CC Thinnes, ...
Kidney international 92 (4), 900-908, 2017
252017
Tetracyanoresorcin [4] arene selectively recognises trimethyllysine and inhibits its enzyme-catalysed demethylation
H Peacock, CC Thinnes, A Kawamura, AD Hamilton
Supramolecular Chemistry 28 (5-6), 575-581, 2016
212016
A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1
N Laurieri, JE Egleton, A Varney, CC Thinnes, CE Quevedo, PT Seden, ...
PLoS One 8 (8), e70600, 2013
212013
Consortium, N.-P.(2020). Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions
F Baldini, J Hertel, E Sandt, CC Thinnes, L Neuberger-Castillo, L Pavelka, ...
BMC Biol 18 (1), 62, 0
13
Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding
CC Thinnes, CT Lohans, MI Abboud, TL Yeh, A Tumber, RP Nowak, ...
Chemistry–A European Journal 25 (8), 2019-2024, 2019
92019
Inhibition of JMJD6 by 2‐oxoglutarate mimics
MS Islam, CC Thinnes, JP Holt‐Martyn, R Chowdhury, MA McDonough, ...
ChemMedChem 17 (1), e202100398, 2022
62022
APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites
A Heinken, TO Hulshof, B Nap, F Martinelli, A Basile, A O'Brolchain, ...
bioRxiv, 2023
52023
Parkinson’s disease-associated alterations of the gut microbiome can invoke disease-relevant metabolic changes
F Baldini, J Hertel, E Sandt, CC Thinnes, L Neuberger-Castillo, L Pavelka, ...
bioRxiv, 691030, 2019
32019
Epigenetic drug discovery: Prospects in terms of technology, market, and organizational capabilities
CC Thinnes, MJ Ventresca
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014
2014
The system can't perform the operation now. Try again later.
Articles 1–20