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Cyrille C. Thinnes
Cyrille C. Thinnes
Research Fellow, University of Galway
Verified email at universityofgalway.ie - Homepage
Title
Cited by
Cited by
Year
Targeting histone lysine demethylases—progress, challenges, and the future
CC Thinnes, KS England, A Kawamura, R Chowdhury, CJ Schofield, ...
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (12 …, 2014
2142014
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials
TL Yeh, TM Leissing, MI Abboud, CC Thinnes, O Atasoylu, JP Holt-Martyn, ...
Chemical science 8 (11), 7651-7668, 2017
1972017
5-Carboxy-8-hydroxyquinoline is a broad spectrum 2-oxoglutarate oxygenase inhibitor which causes iron translocation
RJ Hopkinson, A Tumber, C Yapp, R Chowdhury, WS Aik, KH Che, XS Li, ...
Chemical science 4 (8), 3110-3117, 2013
1702013
Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions
F Baldini, J Hertel, E Sandt, CC Thinnes, L Neuberger-Castillo, L Pavelka, ...
BMC biology 18, 1-21, 2020
1632020
Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models
SS Karuppagounder, I Alim, SJ Khim, MW Bourassa, SF Sleiman, R John, ...
Science translational medicine 8 (328), 328ra29-328ra29, 2016
1252016
Integrated analyses of microbiome and longitudinal metabolome data reveal microbial-host interactions on sulfur metabolism in Parkinson’s disease
J Hertel, AC Harms, A Heinken, F Baldini, CC Thinnes, E Glaab, ...
Cell reports 29 (7), 1767-1777. e8, 2019
1172019
Glucose metabolism and oxygen availability govern reactivation of the latent human retrovirus HTLV-1
A Kulkarni, M Mateus, CC Thinnes, JS McCullagh, CJ Schofield, ...
Cell chemical biology 24 (11), 1377-1387. e3, 2017
662017
Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases
CC Thinnes, A Tumber, C Yapp, G Scozzafava, T Yeh, MC Chan, TA Tran, ...
Chemical Communications 51 (84), 15458-15461, 2015
502015
Genome-scale metabolic modeling of the human microbiome in the era of personalized medicine
A Heinken, A Basile, J Hertel, C Thinnes, I Thiele
Annual review of microbiology 75, 199-222, 2021
382021
Structure of the ribosomal oxygenase OGFOD1 provides insights into the regio-and stereoselectivity of prolyl hydroxylases
S Horita, JS Scotti, C Thinnes, YS Mottaghi-Taromsari, A Thalhammer, ...
Structure 23 (4), 639-652, 2015
352015
Structure–activity relationships and colorimetric properties of specific probes for the putative cancer biomarker human arylamine N-acetyltransferase 1
JE Egleton, CC Thinnes, PT Seden, N Laurieri, SP Lee, KS Hadavizadeh, ...
Bioorganic & medicinal chemistry 22 (11), 3030-3054, 2014
282014
Complement C1q is hydroxylated by collagen prolyl 4 hydroxylase and is sensitive to off-target inhibition by prolyl hydroxylase domain inhibitors that stabilize hypoxia …
S Kiriakidis, SS Hoer, N Burrows, G Biddlecome, MN Khan, CC Thinnes, ...
Kidney international 92 (4), 900-908, 2017
222017
A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1
N Laurieri, JE Egleton, A Varney, CC Thinnes, CE Quevedo, PT Seden, ...
PLoS One 8 (8), e70600, 2013
222013
Tetracyanoresorcin [4] arene selectively recognises trimethyllysine and inhibits its enzyme-catalysed demethylation
H Peacock, CC Thinnes, A Kawamura, AD Hamilton
Supramolecular Chemistry 28 (5-6), 575-581, 2016
212016
Consortium NP (2020) Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions
F Baldini, J Hertel, E Sandt, CC Thinnes, L Neuberger-Castillo, L Pavelka, ...
BMC Biol 18 (1), 62, 0
11
Selective inhibitors of a human prolyl hydroxylase (OGFOD1) involved in ribosomal decoding
CC Thinnes, CT Lohans, MI Abboud, TL Yeh, A Tumber, RP Nowak, ...
Chemistry–A European Journal 25 (8), 2019-2024, 2019
72019
Inhibition of JMJD6 by 2‐Oxoglutarate Mimics
MS Islam, CC Thinnes, JP Holt‐Martyn, R Chowdhury, MA McDonough, ...
ChemMedChem 17 (1), e202100398, 2022
62022
Parkinson’s disease-associated alterations of the gut microbiome can invoke disease-relevant metabolic changes
F Baldini, J Hertel, E Sandt, CC Thinnes, L Neuberger-Castillo, L Pavelka, ...
bioRxiv, 691030, 2019
32019
APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple continents, age groups, and body sites
A Heinken, TO Hulshof, B Nap, F Martinelli, A Basile, A O'Brolchain, ...
bioRxiv, 2023
22023
Epigenetic drug discovery: Prospects in terms of technology, market, and organizational capabilities
CC Thinnes, MJ Ventresca
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014
2014
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Articles 1–20