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David Guertin
David Guertin
Verified email at umassmed.edu - Homepage
Title
Cited by
Cited by
Year
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov, DA Guertin, SM Ali, DM Sabatini
Science 307 (5712), 1098-1101, 2005
78242005
CellProfiler: image analysis software for identifying and quantifying cell phenotypes
AE Carpenter, TR Jones, MR Lamprecht, C Clarke, IH Kang, O Friman, ...
Genome biology 7, 1-11, 2006
49402006
Defining the role of mTOR in cancer
DA Guertin, DM Sabatini
Cancer cell 12 (1), 9-22, 2007
33482007
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
DD Sarbassov, SM Ali, DH Kim, DA Guertin, RR Latek, ...
Current biology 14 (14), 1296-1302, 2004
31792004
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCα, but not S6K1
DA Guertin, DM Stevens, CC Thoreen, AA Burds, NY Kalaany, J Moffat, ...
Developmental cell 11 (6), 859-871, 2006
18132006
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity
DW Lamming, L Ye, P Katajisto, MD Goncalves, M Saitoh, DM Stevens, ...
science 335 (6076), 1638-1643, 2012
11902012
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway
TR Peterson, SS Sengupta, TE Harris, AE Carmack, SA Kang, E Balderas, ...
Cell 146 (3), 408-420, 2011
11552011
An expanding role for mTOR in cancer
DA Guertin, DM Sabatini
Trends in molecular medicine 11 (8), 353-361, 2005
6952005
The pharmacology of mTOR inhibition
DA Guertin, DM Sabatini
Science signaling 2 (67), pe24-pe24, 2009
6512009
mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice
DA Guertin, DM Stevens, M Saitoh, S Kinkel, K Crosby, JH Sheen, ...
Cancer cell 15 (2), 148-159, 2009
4632009
PTEN loss in the Myf5 lineage redistributes body fat and reveals subsets of white adipocytes that arise from Myf5 precursors
J Sanchez-Gurmaches, CM Hung, CA Sparks, Y Tang, H Li, DA Guertin
Cell metabolism 16 (3), 348-362, 2012
3772012
Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy
CA Sparks, DA Guertin
Oncogene 29 (26), 3733-3744, 2010
3562010
Cytokinesis in eukaryotes
DA Guertin, S Trautmann, D McCollum
Microbiology and Molecular Biology Reviews 66 (2), 155-178, 2002
3252002
Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed
J Sanchez-Gurmaches, DA Guertin
Nature communications 5 (1), 4099, 2014
3212014
T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming
K Yang, S Shrestha, H Zeng, PWF Karmaus, G Neale, P Vogel, ...
Immunity 39 (6), 1043-1056, 2013
3202013
Spatiotemporal structure of cell fate decisions in murine neural crest
R Soldatov, M Kaucka, ME Kastriti, J Petersen, T Chontorotzea, ...
Science 364 (6444), eaas9536, 2019
2932019
Adipocyte lineages: tracing back the origins of fat
J Sanchez-Gurmaches, DA Guertin
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (3), 340-351, 2014
2662014
Emerging complexities in adipocyte origins and identity
J Sanchez-Gurmaches, CM Hung, DA Guertin
Trends in cell biology 26 (5), 313-326, 2016
2152016
The role of the sid1p kinase and cdc14p in regulating the onset of cytokinesis in fission yeast
DA Guertin, L Chang, F Irshad, KL Gould, D McCollum
The EMBO journal 19 (8), 1803-1815, 2000
2122000
mTOR-dependent cell survival mechanisms
CM Hung, L Garcia-Haro, CA Sparks, DA Guertin
Cold Spring Harbor perspectives in biology 4 (12), a008771, 2012
2032012
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Articles 1–20