| Global translational responses to oxidative stress impact upon multiple levels of protein synthesis D Shenton, JB Smirnova, JN Selley, K Carroll, SJ Hubbard, GD Pavitt, ... Journal of Biological Chemistry 281 (39), 29011-29021, 2006 | 443 | 2006 |
| Tight binding of the phosphorylated α subunit of initiation factor 2 (eIF2α) to the regulatory subunits of guanine nucleotide exchange factor eIF2B is required for inhibition … T Krishnamoorthy, GD Pavitt, FAN Zhang, TE Dever, AG Hinnebusch Molecular and cellular biology 21 (15), 5018-5030, 2001 | 429 | 2001 |
| The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression TA Owen-Hughes, GD Pavitt, DS Santos, JM Sidebotham, CSJ Hulton, ... Cell 71 (2), 255-265, 1992 | 369 | 1992 |
| Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria CSJ Hulton, A Seirafi, JCD Hinton, JM Sidebotham, L Waddell, GD Pavitt, ... Cell 63 (3), 631-642, 1990 | 351 | 1990 |
| eIF2 independently binds two distinct eIF2B subcomplexes that catalyze and regulate guanine–nucleotide exchange GD Pavitt, KVA Ramaiah, SR Kimball, AG Hinnebusch Genes & development 12 (4), 514-526, 1998 | 347 | 1998 |
| Conserved bipartite motifs in yeast eIF5 and eIF2Bϵ, GTPase-activating and GDP–GTP exchange factors in translation initiation, mediate binding to their common substrate eIF2 K Asano, T Krishnamoorthy, L Phan, GD Pavitt, AG Hinnebusch The EMBO journal 18 (6), 1673-1688, 1999 | 263 | 1999 |
| Protein H1: a role for chromatin structure in the regulation of bacterial gene expression and virulence? CF Higgins, JCD Hinton, CSJ Hulton, T Owen‐Hughes, GD Pavitt, ... Molecular microbiology 4 (12), 2007-2012, 1990 | 230 | 1990 |
| Protein synthesis initiation in eukaryotic cells WC Merrick, GD Pavitt Cold Spring Harbor perspectives in biology 10 (12), a033092, 2018 | 229 | 2018 |
| Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma P Falletta, L Sanchez-del-Campo, J Chauhan, M Effern, A Kenyon, ... Genes & development 31 (1), 18-33, 2017 | 198 | 2017 |
| New insights into translational regulation in the endoplasmic reticulum unfolded protein response GD Pavitt, D Ron Cold Spring Harbor perspectives in biology 4 (6), a012278, 2012 | 183 | 2012 |
| eIF2B, a mediator of general and gene-specific translational control GD Pavitt Biochemical Society Transactions 33 (6), 1487-1492, 2005 | 173 | 2005 |
| Homologous segments in three subunits of the guanine nucleotide exchange factor eIF2B mediate translational regulation by phosphorylation of eIF2 GD Pavitt, W Yang, AG Hinnebusch Molecular and cellular biology 17 (3), 1298-1313, 1997 | 167 | 1997 |
| Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae TE Dever, TG Kinzy, GD Pavitt Genetics 203 (1), 65-107, 2016 | 143 | 2016 |
| Characterization of the minimal catalytic domain within eIF2B: the guanine-nucleotide exchange factor for translation initiation E Gomez, SS Mohammad, GD Pavitt The EMBO journal 21 (19), 5292-5301, 2002 | 143 | 2002 |
| Expression and mutational analysis of the nucleoid‐associated protein H‐NS of Salmonella typhimurium JCD Hinton, DS Santos, A Seirafi, CSJ Hulton, GD Pavitt, CF Higgins Molecular microbiology 6 (16), 2327-2337, 1992 | 138 | 1992 |
| Mutations causing childhood ataxia with central nervous system hypomyelination reduce eukaryotic initiation factor 2B complex formation and activity JP Richardson, SS Mohammad, GD Pavitt Molecular and cellular biology 24 (6), 2352-2363, 2004 | 135 | 2004 |
| Regulation of guanine nucleotide exchange through phosphorylation of eukaryotic initiation factor eIF2α: role of the α-and δ-subunits of eIF2B SR Kimball, JR Fabian, GD Pavitt, AG Hinnebusch, LS Jefferson Journal of Biological Chemistry 273 (21), 12841-12845, 1998 | 134 | 1998 |
| eIF5 has GDI activity necessary for translational control by eIF2 phosphorylation MD Jennings, GD Pavitt Nature 465 (7296), 378-381, 2010 | 132 | 2010 |
| Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways JB Smirnova, JN Selley, F Sanchez-Cabo, K Carroll, AA Eddy, ... Molecular and cellular biology 25 (21), 9340-9349, 2005 | 123 | 2005 |
| Identification of domains and residues within the ɛ subunit of eukaryotic translation initiation factor 2B (eIF2Bɛ) required for guanine nucleotide exchange reveals a novel … E Gomez, GD Pavitt Molecular and cellular biology 20 (11), 3965-3976, 2000 | 115 | 2000 |
Mark AsheThe University of ManchesterVerified email at manchester.ac.uk
