Radosław P. Nowak
Radosław P. Nowak
Research Fellow, Dana-Farber Cancer Institute
Verified email at crystal.harvard.edu - Homepage
Cited by
Cited by
The roles of Jumonji-type oxygenases in human disease
C Johansson, A Tumber, KH Che, P Cain, R Nowak, C Gileadi, ...
Epigenomics 6 (1), 89-120, 2014
Plasticity in binding confers selectivity in ligand-induced protein degradation
RP Nowak, SL DeAngelo, D Buckley, Z He, KA Donovan, J An, N Safaee, ...
Nature chemical biology 14 (7), 706-714, 2018
Structural analysis of human KDM5B guides histone demethylase inhibitor development
C Johansson, S Velupillai, A Tumber, A Szykowska, ES Hookway, ...
Nature chemical biology 12 (7), 539, 2016
Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray Syndrome
KA Donovan, J An, RP Nowak, JC Yuan, EC Fink, BC Berry, BL Ebert, ...
Elife 7, e38430, 2018
A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density
NM Pearce, T Krojer, AR Bradley, P Collins, RP Nowak, R Talon, ...
Nature communications 8 (1), 1-8, 2017
Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance
W Zhou, AT Whiteley, CC de Oliveira Mann, BR Morehouse, RP Nowak, ...
Cell 174 (2), 300-311. e11, 2018
Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML
M Brand, B Jiang, S Bauer, KA Donovan, Y Liang, ES Wang, RP Nowak, ...
Cell chemical biology 26 (2), 300-306. e9, 2019
Chemically induced degradation of anaplastic lymphoma kinase (ALK)
CE Powell, Y Gao, L Tan, KA Donovan, RP Nowak, A Loehr, M Bahcall, ...
Journal of medicinal chemistry 61 (9), 4249-4255, 2018
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells
A Tumber, A Nuzzi, ES Hookway, SB Hatch, S Velupillai, C Johansson, ...
Cell chemical biology 24 (3), 371-380, 2017
Docking and linking of fragments to discover Jumonji histone demethylase inhibitors
M Korczynska, DD Le, N Younger, E Gregori-Puigjané, A Tumber, ...
Journal of medicinal chemistry 59 (4), 1580-1598, 2016
Bruton tyrosine kinase degradation as a therapeutic strategy for cancer
D Dobrovolsky, ES Wang, S Morrow, C Leahy, T Faust, RP Nowak, ...
Blood, The Journal of the American Society of Hematology 133 (9), 952-961, 2019
Exploring Targeted Degradation Strategy for Oncogenic KRASG12C
M Zeng, Y Xiong, N Safaee, RP Nowak, KA Donovan, CJ Yuan, B Nabet, ...
Cell Chemical Biology 27 (1), 19-31. e6, 2020
Introduction to structural studies on 2-oxoglutarate-dependent oxygenases and related enzymes. 2-Oxoglutarate-Dependent Oxygenases, eds Hausinger RP, Schofield CJ
WS Aik, R Chowdhury, IJ Clifton, RJ Hopkinson, T Leissing, ...
R. Soc. Chem, 59-94, 2015
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
TB Faust, H Yoon, RP Nowak, KA Donovan, Z Li, Q Cai, NA Eleuteri, ...
Nature chemical biology 16 (1), 7-14, 2020
Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations
M de Wispelaere, G Du, KA Donovan, T Zhang, NA Eleuteri, JC Yuan, ...
Nature communications 10 (1), 1-11, 2019
Introduction to Structural Studies on 2-Oxoglutarate-Dependent Oxygenases and Related Enzymes
WS Aik, R Chowdhury, IJ Clifton, RJ Hopkinson, T Leissing, ...
2-Oxoglutarate-Dependent Oxygenases, 59-94, 2015
Studies on the Interaction of the Histone Demethylase KDM5B with Tricarboxylic Acid Cycle Intermediates
H Tarhonskaya, RP Nowak, C Johansson, A Szykowska, A Tumber, ...
Journal of Molecular Biology 429 (19), 2895-2906, 2017
An integrated approach to quantitative modelling in angiogenesis research
AJ Connor, RP Nowak, E Lorenzon, M Thomas, F Herting, S Hoert, ...
Journal of The Royal Society Interface 12 (110), 20150546, 2015
Advances and challenges in understanding histone demethylase biology
RP Nowak, A Tumber, C Johansson, KH Che, P Brennan, D Owen, ...
Current Opinion in Chemical Biology 33, 151-159, 2016
Development and Characterization of a Wee1 Kinase Degrader
Z Li, BJ Pinch, CM Olson, KA Donovan, RP Nowak, CE Mills, DA Scott, ...
Cell Chemical Biology 27 (1), 57-65. e9, 2020
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