| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10670 | 2021 |
| C. elegans major fats are stored in vesicles distinct from lysosome-related organelles EJ O'Rourke, AA Soukas, CE Carr, G Ruvkun Cell metabolism 10 (5), 430-435, 2009 | 485 | 2009 |
| Fat Metabolism Links Germline Stem Cells and Longevity in C. elegans MC Wang, EJ O'Rourke, G Ruvkun science 322 (5903), 957-960, 2008 | 441 | 2008 |
| MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability EJ O’Rourke, G Ruvkun Nature cell biology 15 (6), 668-676, 2013 | 317 | 2013 |
| An image analysis toolbox for high-throughput C. elegans assays C Wählby, L Kamentsky, ZH Liu, T Riklin-Raviv, AL Conery, EJ O'Rourke, ... Nature methods 9 (7), 714-716, 2012 | 196 | 2012 |
| ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy EJ O'Rourke, P Kuballa, R Xavier, G Ruvkun Genes and Development 27 (4), 429-440, 2013 | 195 | 2013 |
| Guidelines for monitoring autophagy in Caenorhabditis elegans H Zhang, JT Chang, B Guo, M Hansen, K Jia, AL Kovács, C Kumsta, ... Autophagy 11 (1), 9-27, 2015 | 148 | 2015 |
| Pathogen DNA as target for host-generated oxidative stress: Role for repair of bacterial DNA damage in Helicobacter pylori colonization EJ O'Rourke, C Chevalier, AV Pinto, JM Thiberge, L Ielpi, A Labigne, ... Proceedings of the National Academy of Sciences 100 (5), 2789-2794, 2003 | 140 | 2003 |
| A lysosome-centered view of nutrient homeostasis VK Mony, S Benjamin, EJ O'Rourke Autophagy 12 (4), 619-631, 2016 | 113 | 2016 |
| In Vivo Behavior of a Helicobacter pylori SS1 nixA Mutant with Reduced Urease Activity KJ Nolan, DJ McGee, HM Mitchell, T Kolesnikow, JM Harro, J O'Rourke, ... Infection and immunity 70 (2), 685-691, 2002 | 95 | 2002 |
| Protective immunity against Helicobacter is characterized by a unique transcriptional signature A Mueller, J O'Rourke, P Chu, CC Kim, P Sutton, A Lee, S Falkow Proceedings of the National Academy of Sciences 100 (21), 12289-12294, 2003 | 75 | 2003 |
| High-and low-throughput scoring of fat mass and body fat distribution in C. elegans C Wählby, AL Conery, MA Bray, L Kamentsky, J Larkins-Ford, ... Methods 68 (3), 492-499, 2014 | 72 | 2014 |
| Crystal structures of 3‐methyladenine DNA glycosylase MagIII and the recognition of alkylated bases BF Eichman, EJ O'Rourke, JP Radicella, T Ellenberger The EMBO journal, 2003 | 64 | 2003 |
| Whole-Animal High-Throughput Screens: The C. elegans Model EJ O’Rourke, AL Conery, TI Moy Cell-Based Assays for High-Throughput Screening: Methods and Protocols, 57-75, 2009 | 60 | 2009 |
| A novel 3-methyladenine DNA glycosylase from Helicobacter pylori defines a new class within the endonuclease III family of base excision repair glycosylases EJ O'Rourke, C Chevalier, S Boiteux, A Labigne, L Ielpi, JP Radicella Journal of Biological Chemistry 275 (26), 20077-20083, 2000 | 58 | 2000 |
| Gravity Force Transduced by the MEC-4/MEC-10 DEG/ENaC Channel Modulates DAF-16/FoxO Activity in Caenorhabditis elegans N Kim, CM Dempsey, CJ Kuan, JV Zoval, E O'Rourke, G Ruvkun, ... Genetics 177 (2), 835-845, 2007 | 52 | 2007 |
| What are housekeeping genes? CJ Joshi, W Ke, A Drangowska-Way, EJ O’Rourke, NE Lewis PLoS computational biology 18 (7), e1010295, 2022 | 46 | 2022 |
| Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion W Ke, JA Saba, CH Yao, MA Hilzendeger, A Drangowska-Way, C Joshi, ... Nature communications 11 (1), 2587, 2020 | 36 | 2020 |
| Evidence for the Active Role of a Novel Nuclease from Helicobacter pylori in the Horizontal Transfer of Genetic Information EJ O'Rourke, AV Pinto, EA Petroni, ME Tolmasky, L Ielpi Journal of bacteriology 186 (9), 2586-2593, 2004 | 29 | 2004 |
| Inferring a spatial code of cell-cell interactions across a whole animal body E Armingol, A Ghaddar, CJ Joshi, H Baghdassarian, I Shamie, J Chan, ... PLoS computational biology 18 (11), e1010715, 2022 | 28 | 2022 |
Gary RuvkunProfessor of Genetics, Harvard Medical SchoolVerified email at molbio.mgh.harvard.edu
