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Alex Guseman
Alex Guseman
NIH MOSAIC Scholar, University of California San Diego
Verified email at terpmail.umd.edu
Title
Cited by
Cited by
Year
Osmotic shock induced protein destabilization in living cells and its reversal by glycine betaine
SS Stadmiller, AH Gorensek-Benitez, AJ Guseman, GJ Pielak
Journal of molecular biology 429 (8), 1155-1161, 2017
1032017
Protein shape modulates crowding effects
AJ Guseman, GM Perez Goncalves, SL Speer, GB Young, GJ Pielak
Proceedings of the National Academy of Sciences 115 (43), 10965-10970, 2018
842018
Surface charge modulates protein–protein interactions in physiologically relevant environments
AJ Guseman, SL Speer, GM Perez Goncalves, GJ Pielak
Biochemistry 57 (11), 1681-1684, 2018
712018
The intracellular environment affects protein–protein interactions
SL Speer, W Zheng, X Jiang, IT Chu, AJ Guseman, M Liu, GJ Pielak, C Li
Proceedings of the National Academy of Sciences 118 (11), e2019918118, 2021
652021
Intracellular p H modulates quinary structure
RD Cohen, AJ Guseman, GJ Pielak
Protein Science 24 (11), 1748-1755, 2015
642015
Protecting activity of desiccated enzymes
S Piszkiewicz, KH Gunn, O Warmuth, A Propst, A Mehta, KH Nguyen, ...
Protein Science 28 (5), 941-951, 2019
622019
Cosolute and crowding effects on a side-by-side protein dimer
AJ Guseman, GJ Pielak
Biochemistry 56 (7), 971-976, 2017
542017
Multi-drug resistance transporters and a mechanism-based strategy for assessing risks of pesticide combinations to honey bees
AJ Guseman, K Miller, G Kunkle, GP Dively, JS Pettis, JD Evans, ...
PloS one 11 (2), e0148242, 2016
362016
Restricted myeloperoxidase epitopes drive the adaptive immune response in MPO-ANCA vasculitis
ME Free, KG Stember, JJ Hess, EA McInnis, O Lardinois, SL Hogan, Y Hu, ...
Journal of autoimmunity 106, 102306, 2020
282020
Visualizing Proteins in Mammalian Cells by 19F NMR Spectroscopy
W Zhu, AJ Guseman, F Bhinderwala, M Lu, XC Su, AM Gronenborn
Angewandte Chemie International Edition 61 (23), e202201097, 2022
252022
Controlling and quantifying protein concentration in Escherichia coli
SL Speer, AJ Guseman, JB Patteson, BM Ehrmann, GJ Pielak
Protein science 28 (7), 1307-1311, 2019
192019
Protein stability and weak intracellular interactions
AJ Guseman, GJ Pielak
162019
Thermodynamic consequences of Tyr to Trp mutations in the cation–π-mediated binding of trimethyllysine by the HP1 chromodomain
MW Krone, KI Albanese, GO Leighton, CQ He, GY Lee, M Garcia-Borràs, ...
Chemical science 11 (13), 3495-3500, 2020
142020
Assessing the structures and interactions of γD-crystallin deamidation variants
AJ Guseman, MJ Whitley, JJ González, N Rathi, M Ambarian, ...
Structure 29 (3), 284-291. e3, 2021
112021
Isomerization as the secret Achilles' heel of long-lived proteins
AJ Guseman, AM Gronenborn
Journal of Biological Chemistry 294 (19), 7556-7557, 2019
62019
Targeting spike glycans to inhibit SARS-CoV2 viral entry
AJ Guseman, LJ Rennick, S Nambulli, CN Roy, DR Martinez, DT Yang, ...
Proceedings of the National Academy of Sciences 120 (38), e2301518120, 2023
32023
The role of cryptic ancestral symmetry in histone folding mechanisms across Eukarya and Archaea
H Zhao, H Wu, A Guseman, D Abeykoon, CM Camara, Y Dalal, ...
PLOS Computational Biology 20 (1), e1011721, 2024
12024
Probing effects of site‐specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis
SL Heath, AJ Guseman, AM Gronenborn, WS Horne
Protein Science 33 (3), e4883, 2024
2024
Targeting Spike Glycans to Inhibit Viral Entry
A Guseman, L Rennick, S Nambulli, C Roy, D Martinez, D Yang, ...
PROTEIN SCIENCE 32 (12), 2023
2023
Investigating the structural mechanism of gamma-D crystallin aggregation
S Volz, AJ Guseman, S Marqusee, AM Gronenborn
Biophysical Journal 122 (3), 336a-337a, 2023
2023
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Articles 1–20