Polyamine control of translation elongation regulates start site selection on antizyme inhibitor mRNA via ribosome queuing IP Ivanov, BS Shin, G Loughran, I Tzani, SK Young-Baird, C Cao, ... Molecular cell 70 (2), 254-264. e6, 2018 | 130 | 2018 |
Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response G Loughran, I Jungreis, I Tzani, M Power, RI Dmitriev, IP Ivanov, M Kellis, ... Journal of Biological Chemistry 293 (12), 4434-4444, 2018 | 73 | 2018 |
AMD1 mRNA employs ribosome stalling as a mechanism for molecular memory formation MM Yordanova, G Loughran, AV Zhdanov, M Mariotti, SJ Kiniry, ... Nature 553 (7688), 356-360, 2018 | 73 | 2018 |
Systematic analysis of the PTEN 5′ leader identifies a major AUU initiated proteoform I Tzani, IP Ivanov, DE Andreev, RI Dmitriev, KA Dean, PV Baranov, ... Open biology 6 (5), 150203, 2016 | 53 | 2016 |
Tracing production instability in a clonally derived CHO cell line using single‐cell transcriptomics I Tzani, N Herrmann, S Carillo, CA Spargo, R Hagan, N Barron, J Bones, ... Biotechnology and Bioengineering 118 (5), 2016-2030, 2021 | 21 | 2021 |
Expanding the Chinese hamster ovary cell long noncoding RNA transcriptome using RNASeq K Motheramgari, R Valdés‐Bango Curell, I Tzani, C Gallagher, ... Biotechnology and Bioengineering 117 (10), 3224-3231, 2020 | 12 | 2020 |
Subphysiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells I Tzani, C Monger, K Motheramgari, C Gallagher, R Hagan, P Kelly, ... Biotechnology and Bioengineering 117 (8), 2489-2503, 2020 | 8 | 2020 |
Understanding biopharmaceutical production at single nucleotide resolution using ribosome footprint profiling I Tzani, C Monger, P Kelly, N Barron, RM Kelly, C Clarke Current opinion in biotechnology 53, 182-190, 2018 | 8 | 2018 |
Understanding the transcriptional response to ER stress in Chinese hamster ovary cells using multiplexed single cell RNA-seq I Tzani, M Castro-Rivadeneyra, S Boi, C Clarke bioRxiv, 2022.03. 31.486542, 2022 | 2 | 2022 |
Annotation of the non-canonical translatome reveals that CHO cell microproteins are a new class of mAb drug product impurity M Castro-Rivadeneyra, I Tzani, P Kelly, L Strasser, F Guapo, C Tierney, ... | | 2022 |
Found in translation: Microproteins are a new class of potential host cell impurity in mAb drug products M Castro-Rivadeneyra, I Tzani, P Kelly, L Strasser, F Guapo, C Tierney, ... bioRxiv, 2022.01. 20.475618, 2022 | | 2022 |
A study of translation regulation in cancer by application of ribosome profiling I Tzani University College Cork, 2016 | | 2016 |