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Michael D Jones
Michael D Jones
Scientist, Novartis Institutes for Biomedical Research
Bestätigte E-Mail-Adresse bei novartis.com
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Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 492 (7428), 290-290, 2012
7740*2012
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-607, 2012
77042012
Next-generation characterization of the cancer cell line encyclopedia
M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ...
Nature 569 (7757), 503-508, 2019
23912019
Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening
ER McDonald, A de Weck, MR Schlabach, E Billy, KJ Mavrakis, ...
Cell 170 (3), 577-592. e10, 2017
5972017
CRISPR screens provide a comprehensive assessment of cancer vulnerabilities but generate false-positive hits for highly amplified genomic regions
DM Munoz, PJ Cassiani, L Li, E Billy, JM Korn, MD Jones, J Golji, ...
Cancer discovery, CD-16-0178, 2016
3772016
Use of mass spectrometry to identify protein biomarkers of disease severity in the synovial fluid and serum of patients with rheumatoid arthritis
H Liao, J Wu, E Kuhn, W Chin, B Chang, MD Jones, S O'Neil, KR Clauser, ...
Arthritis & Rheumatism 50 (12), 3792-3803, 2004
3312004
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
JN Spradlin, X Hu, CC Ward, SM Brittain, MD Jones, L Ou, M To, ...
Nature chemical biology 15 (7), 747-755, 2019
3092019
Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss
H Liu, J Golji, LK Brodeur, FS Chung, JT Chen, CP Bullock, MD Jones, ...
Nature Medicine, 1, 2018
2512018
Contribution of polycomb homologues Bmi-1 and Mel-18 to medulloblastoma pathogenesis
D Wiederschain, L Chen, B Johnson, K Bettano, D Jackson, J Taraszka, ...
Molecular and cellular biology 27 (13), 4968-4979, 2007
1452007
A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patients
R Tiedt, E Degenkolbe, P Furet, BA Appleton, S Wagner, J Schoepfer, ...
Cancer research 71 (15), 5255-5264, 2011
1272011
Determination of disulfide bonds in highly bridged disulfide-linked peptides by matrix-assisted laser desorption/ionization mass spectrometry with postsource decay
MD Jones, SD Patterson, HS Lu
Analytical chemistry 70 (1), 136-143, 1998
1061998
Characterization of activating mutations of NOTCH3 in T-cell acute lymphoblastic leukemia and anti-leukemic activity of NOTCH3 inhibitory antibodies
P Bernasconi-Elias, T Hu, D Jenkins, B Firestone, S Gans, E Kurth, ...
Oncogene, 2016
892016
Manumycin polyketides act as molecular glues between UBR7 and P53
Y Isobe, M Okumura, LM McGregor, SM Brittain, MD Jones, X Liang, ...
Nature chemical biology 16 (11), 1189-1198, 2020
882020
Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC
L Boike, AG Cioffi, FC Majewski, J Co, NJ Henning, MD Jones, G Liu, ...
Cell chemical biology 28 (1), 4-13. e17, 2021
822021
Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Allosteric and Mutant Specific Inhibitors of IDH1
JR Levell, T Caferro, G Chenail, I Dix, J Dooley, B Firestone, PD Fortin, ...
ACS Medicinal Chemistry Letters, 2016
552016
Heparin is essential for a single keratinocyte growth factor molecule to bind and form a complex with two molecules of the extracellular domain of its receptor
YR Hsu, R Nybo, JK Sullivan, V Costigan, CS Spahr, C Wong, M Jones, ...
Biochemistry 38 (8), 2523-2534, 1999
541999
Optimization of capillary chromatography ion trap‐mass spectrometry for identification of gel‐separated proteins
PL Courchesne, MD Jones, JH Robinson, CS Spahr, S McCracken, ...
Electrophoresis 19 (6), 956-967, 1998
541998
Post-translational processing of membrane-associated neu differentiation factor proisoforms expressed in mammalian cells
HS Lu, S Hara, LWI Wong, MD Jones, V Katta, G Trail, A Zou, D Brankow, ...
Journal of Biological Chemistry 270 (9), 4775-4783, 1995
471995
Peptide map analysis of recombinant human granulocyte colony stimulating factor: elimination of methionine modification and nonspecific cleavages
MD Jones, LA Merewether, CL Clogston, HS Lu
Analytical biochemistry 216 (1), 135-146, 1994
471994
Determination of tumor necrosis factor binding protein disulfide structure: deviation of the fourth domain structure from the TNFR/NGFR family cysteine-rich region signature
MD Jones, J Hunt, JL Liu, SD Patterson, T Kohno, HS Lu
Biochemistry 36 (48), 14914-14923, 1997
411997
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