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Tanya Major
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An update on the genetics of hyperuricaemia and gout
TJ Major, N Dalbeth, EA Stahl, TR Merriman
Nature Reviews Rheumatology 14 (6), 341-353, 2018
2412018
Evaluation of the diet wide contribution to serum urate levels: meta-analysis of population based cohorts
TJ Major, RK Topless, N Dalbeth, TR Merriman
bmj 363, 2018
2022018
Mendelian randomization analysis associates increased serum urate, due to genetic variation in uric acid transporters, with improved renal function
K Hughes, T Flynn, J De Zoysa, N Dalbeth, TR Merriman
Kidney international 85 (2), 344-351, 2014
972014
Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Māori and Pacific (Polynesian) people …
M Krishnan, TJ Major, RK Topless, O Dewes, L Yu, JMD Thompson, ...
Diabetologia 61, 1603-1613, 2018
842018
Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case …
TJ Flynn, A Phipps-Green, JE Hollis-Moffatt, ME Merriman, R Topless, ...
Arthritis research & therapy 15, 1-11, 2013
552013
Mendelian randomization analysis to examine for a causal effect of urate on bone mineral density
N Dalbeth, R Topless, T Flynn, M Cadzow, MJ Bolland, TR Merriman
Journal of Bone and Mineral Research 30 (6), 985-991, 2015
542015
Mendelian randomization provides no evidence for a causal role of serum urate in increasing serum triglyceride levels
H Rasheed, K Hughes, TJ Flynn, TR Merriman
Circulation: Cardiovascular Genetics 7 (6), 830-837, 2014
442014
Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control
J Boocock, M Leask, Y Okada, ...
Human molecular genetics 29 (6), 923-943, 2020
422020
Positive association of tomato consumption with serum urate: support for tomato consumption as an anecdotal trigger of gout flares
TJ Flynn, M Cadzow, N Dalbeth, PB Jones, LK Stamp, JH Hindmarsh, ...
BMC musculoskeletal disorders 16, 1-8, 2015
412015
Pleiotropic effect of the ABCG2 gene in gout: involvement in serum urate levels and progression from hyperuricemia to gout
R Wrigley, AJ Phipps-Green, RK Topless, TJ Major, M Cadzow, P Riches, ...
Arthritis research & therapy 22, 1-10, 2020
372020
The relationship between ferritin and urate levels and risk of gout
T Fatima, C McKinney, TJ Major, LK Stamp, N Dalbeth, C Iverson, ...
Arthritis research & therapy 20, 1-9, 2018
372018
Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout …
A Nakayama, M Nakatochi, Y Kawamura, K Yamamoto, H Nakaoka, ...
Annals of the rheumatic diseases 79 (5), 657-665, 2020
332020
The comparative effect of exposure to various risk factors on the risk of hyperuricaemia: diet has a weak causal effect
RKG Topless, TJ Major, JC Florez, JN Hirschhorn, M Cadzow, N Dalbeth, ...
Arthritis research & therapy 23, 1-12, 2021
252021
Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women
RK Topless, TJ Flynn, M Cadzow, LK Stamp, N Dalbeth, MA Black, ...
Frontiers in genetics 6, 162450, 2015
202015
Mediation analysis to understand genetic relationships between habitual coffee intake and gout
J Hutton, T Fatima, TJ Major, R Topless, LK Stamp, TR Merriman, ...
Arthritis Research & Therapy 20, 1-9, 2018
192018
Aotearoa New Zealand Māori and Pacific Population-amplified Gout Risk Variants: CLNK Is a Separate Risk Gene at the SLC2A9 Locus
A Ji, A Shaukat, R Takei, M Bixley, M Cadzow, RK Topless, TJ Major, ...
The Journal of Rheumatology 48 (11), 1736-1744, 2021
132021
Association analysis of the beta-3 adrenergic receptor Trp64Arg (rs4994) polymorphism with urate and gout
T Fatima, S Altaf, A Phipps-Green, R Topless, TJ Flynn, LK Stamp, ...
Rheumatology international 36, 255-261, 2016
132016
Association of gout polygenic risk score with age at disease onset and Tophaceous disease in European and Polynesian men with gout
NA Sumpter, R Takei, M Cadzow, RKG Topless, AJ Phipps‐Green, ...
Arthritis & Rheumatology 75 (5), 816-825, 2023
112023
Dietary sodium modifies serum uric acid concentrations in humans
AS Todd, RJ Walker, RJ MacGinley, J Kelly, TR Merriman, TJ Major, ...
American journal of hypertension 30 (12), 1196-1202, 2017
112017
Re:“Widespread prevalence of a CREBRF variant among Māori and Pacific children is associated with weight and height in early childhood”
TJ Major, M Krishnan, RK Topless, O Dewes, J Thompson, J Zoysa, ...
International Journal of Obesity 42 (7), 1389-1391, 2018
72018
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