APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa RJ Cho, LB Alexandrov, NY Den Breems, VS Atanasova, M Farshchian, ... Science Translational Medicine 10 (455), eaas9668, 2018 | 107 | 2018 |
Functional correction of type VII collagen expression in dystrophic epidermolysis bullosa EM Murauer, Y Gache, IK Gratz, A Klausegger, W Muss, C Gruber, ... Journal of Investigative Dermatology 131 (1), 74-83, 2011 | 106 | 2011 |
Amlexanox enhances premature termination codon read-through in COL7A1 and expression of full length type VII collagen: potential therapy for recessive dystrophic epidermolysis … VS Atanasova, Q Jiang, M Prisco, C Gruber, JP Hofbauer, M Chen, C Has, ... Journal of Investigative Dermatology 137 (9), 1842-1849, 2017 | 91 | 2017 |
Thrombospondin-1 is a major activator of TGF-β signaling in recessive dystrophic epidermolysis bullosa fibroblasts VS Atanasova, RJ Russell, TG Webster, Q Cao, P Agarwal, YZ Lim, ... Journal of Investigative Dermatology 139 (7), 1497-1505. e5, 2019 | 58 | 2019 |
Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin aging JS Breitenbach, M Rinnerthaler, A Trost, M Weber, A Klausegger, ... Aging (Albany NY) 7 (6), 389, 2015 | 54 | 2015 |
Generation of hypoallergenic DNA vaccines by forced ubiquitination: preventive and therapeutic effects in a mouse model of allergy R Bauer, S Scheiblhofer, K Kern, C Gruber, T Stepanoska, T Thalhamer, ... Journal of allergy and clinical immunology 118 (1), 269-276, 2006 | 54 | 2006 |
Improved double-nicking strategies for COL7A1-editing by homologous recombination T Kocher, RN Wagner, A Klausegger, C Guttmann-Gruber, S Hainzl, ... Molecular Therapy-Nucleic Acids 18, 496-507, 2019 | 44 | 2019 |
TGFβ-signaling in squamous cell carcinoma occurring in recessive dystrophic epidermolysis bullosa J Knaup, C Gruber, B Krammer, V Ziegler, J Bauer, T Verwanger Analytical Cellular Pathology 34 (6), 339-353, 2011 | 43 | 2011 |
A novel screening system improves genetic correction by internal exon replacement U Koller, V Wally, LG Mitchell, A Klausegger, EM Murauer, E Mayr, ... Nucleic acids research 39 (16), e108-e108, 2011 | 37 | 2011 |
Gene Editing–Mediated Disruption of Epidermolytic Ichthyosis–Associated KRT10 Alleles Restores Filament Stability in Keratinocytes OP March, T Lettner, A Klausegger, M Ablinger, T Kocher, S Hainzl, ... Journal of Investigative Dermatology 139 (8), 1699-1710. e6, 2019 | 34 | 2019 |
Spliceosome-Mediated RNA Trans-Splicing Facilitates Targeted Delivery of Suicide Genes to Cancer Cells C Gruber, IK Gratz, EM Murauer, E Mayr, U Koller, L Bruckner-Tuderman, ... Molecular Cancer Therapeutics 10 (2), 233-241, 2011 | 34 | 2011 |
Identification of rigosertib for the treatment of recessive dystrophic epidermolysis bullosa–associated squamous cell carcinoma VS Atanasova, C Pourreyron, M Farshchian, M Lawler, CA Brown IV, ... Clinical Cancer Research 25 (11), 3384-3391, 2019 | 32 | 2019 |
Low-dose calcipotriol can elicit wound closure, anti-microbial, and anti-neoplastic effects in epidermolysis bullosa keratinocytes C Guttmann-Gruber, B Tockner, C Scharler, C Hüttner, JE Common, ... Scientific reports 8 (1), 13430, 2018 | 28 | 2018 |
Reduced microbial diversity is a feature of recessive dystrophic epidermolysis bullosa-involved skin and wounds I Fuentes, C Guttmann-Gruber, ASL Tay, JP Hofbauer, SLIJ Denil, ... The Journal of investigative dermatology 138 (11), 2492-2495, 2018 | 27 | 2018 |
The design and optimization of RNA trans-splicing molecules for skin cancer therapy C Gruber, U Koller, EM Murauer, S Hainzl, C Hüttner, T Kocher, AP South, ... Molecular Oncology 7 (6), 1056-1068, 2013 | 25 | 2013 |
A cancer stem cell-like phenotype is associated with miR-10b expression in aggressive squamous cell carcinomas M Wimmer, R Zauner, M Ablinger, J Piñón-Hofbauer, C Guttmann-Gruber, ... Cell Communication and Signaling 18, 1-15, 2020 | 24 | 2020 |
Trans-Splicing Improvement by the Combined Application of Antisense Strategies U Koller, S Hainzl, T Kocher, C Hüttner, A Klausegger, C Gruber, E Mayr, ... International journal of molecular sciences 16 (1), 1179-1191, 2015 | 21 | 2015 |
Epidermolysis Bullosa–a group of skin diseases with different causes but commonalities in gene expression J Knaup, T Verwanger, C Gruber, V Ziegler, JW Bauer, B Krammer Experimental dermatology 21 (7), 526-530, 2012 | 20 | 2012 |
Gene gun immunization with clinically relevant allergens aggravates allergen induced pathology and is contraindicated for allergen immunotherapy S Scheiblhofer, A Stoecklinger, C Gruber, C Hauser-Kronberger, ... Molecular immunology 44 (8), 1879-1887, 2007 | 20 | 2007 |
Targeting of the hNC16A collagen domain to dendritic cells induces tolerance to human type XVII collagen M Ettinger, IK Gratz, C Gruber, C Hauser‐Kronberger, TS Johnson, ... Experimental dermatology 21 (5), 395-398, 2012 | 19 | 2012 |