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Valentin Cracan
Valentin Cracan
Assistant Professor, Scintillon Institute and Scripps Research
Verified email at scripps.edu - Homepage
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Cited by
Cited by
Year
Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging
V Hung, P Zou, HW Rhee, ND Udeshi, V Cracan, T Svinkina, SA Carr, ...
Molecular cell 55 (2), 332-341, 2014
4972014
Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio
DV Titov, V Cracan, RP Goodman, J Peng, Z Grabarek, VK Mootha
Science 352 (6282), 231-235, 2016
3472016
IGF2BP2/IMP2-deficient mice resist obesity through enhanced translation of Ucp1 mRNA and other mRNAs encoding mitochondrial proteins
N Dai, L Zhao, D Wrighting, D Krämer, A Majithia, Y Wang, V Cracan, ...
Cell metabolism 21 (4), 609-621, 2015
1652015
A genetically encoded tool for manipulation of NADP+/NADPH in living cells
V Cracan, DV Titov, H Shen, Z Grabarek, VK Mootha
Nature chemical biology 13 (10), 1088-1095, 2017
902017
Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism
VM Gohil, L Zhu, CD Baker, V Cracan, A Yaseen, M Jain, CB Clish, ...
Journal of Biological Chemistry 288 (49), 35387-35395, 2013
672013
IcmF is a fusion between the radical B12 enzyme isobutyryl-CoA mutase and its G-protein chaperone
V Cracan, D Padovani, R Banerjee
Journal of biological chemistry 285 (1), 655-666, 2010
382010
Visualization of a radical B12 enzyme with its G-protein chaperone
M Jost, V Cracan, PA Hubbard, R Banerjee, CL Drennan
Proceedings of the National Academy of Sciences 112 (8), 2419-2424, 2015
342015
Cobalt and corrinoid transport and biochemistry
V Cracan, R Banerjee
Metallomics and the Cell, 333-374, 2013
332013
Downregulation of the tyrosine degradation pathway extends Drosophila lifespan
AA Parkhitko, D Ramesh, L Wang, D Leshchiner, E Filine, R Binari, ...
Elife 9, e58053, 2020
272020
Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases*♦
M Jost, DA Born, V Cracan, R Banerjee, CL Drennan
Journal of Biological Chemistry 290 (45), 26882-26898, 2015
272015
Novel coenzyme B12-dependent interconversion of isovaleryl-CoA and pivalyl-CoA
V Cracan, R Banerjee
Journal of Biological Chemistry 287 (6), 3723-3732, 2012
272012
Novel B12-Dependent Acyl-CoA Mutases and Their Biotechnological Potential
V Cracan, R Banerjee
Biochemistry 51 (31), 6039-6046, 2012
262012
Engineered and native coenzyme B12-dependent isovaleryl-CoA/pivalyl-CoA mutase
K Kitanishi, V Cracan, R Banerjee
Journal of Biological Chemistry 290 (33), 20466-20476, 2015
122015
Cofactor Editing by the G-protein Metallochaperone Domain Regulates the Radical B12 Enzyme IcmF*♦
Z Li, K Kitanishi, UT Twahir, V Cracan, D Chapman, K Warncke, ...
Journal of Biological Chemistry 292 (10), 3977-3987, 2017
82017
A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells
X Pan, ML Heacock, EN Abdulaziz, S Violante, AL Zuckerman, ...
Nature Chemical Biology, 1-11, 2023
62023
A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis
EN Abdulaziz, TA Bell, B Rashid, ML Heacock, T Begic, OS Skinner, ...
Journal of Biological Chemistry 298 (8), 2022
32022
Protein prostheses for mitochondrial diseases or conditions
V Mootha, D Titov, V Cracan, Z Grabarek
US Patent 11,866,736, 2024
2024
ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits
C Singh, B Jin, N Shrestha, AL Markhard, A Panda, SE Calvo, A Deik, ...
Cell Metabolism 36 (1), 144-158. e7, 2024
2024
UNRAVELING THE ROLE OF REDUCTIVE STRESS IN HEPATIC TRANSCRIPTIONAL REGULATION OF FATTY LIVER DISEASE
B Jin, C Singh, GA Sola, V Cracan, RP Goodman
HEPATOLOGY 78, S1668-S1668, 2023
2023
A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells
ML Heacock, EN Abdulaziz, X Pan, AL Zuckerman, S Violante, C Yao, ...
bioRxiv, 2022.09. 20.508785, 2022
2022
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