A homology model of HIV-1 integrase and analysis of mutations designed to test the model BC Johnson, M Métifiot, A Ferris, Y Pommier, SH Hughes Journal of molecular biology 425 (12), 2133-2146, 2013 | 58 | 2013 |
Molecular dynamics approaches estimate the binding energy of HIV-1 integrase inhibitors and correlate with in vitro activity BC Johnson, M Métifiot, Y Pommier, SH Hughes Antimicrobial agents and chemotherapy 56 (1), 411-419, 2012 | 51 | 2012 |
A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants BC Johnson, GT Pauly, G Rai, D Patel, JD Bauman, HL Baker, K Das, ... Retrovirology 9 (1), 1-11, 2012 | 47 | 2012 |
Activities, Crystal Structures, and Molecular Dynamics of Dihydro-1H-isoindole Derivatives, Inhibitors of HIV-1 Integrase M Métifiot, K Maddali, BC Johnson, S Hare, SJ Smith, XZ Zhao, ... ACS chemical biology 8 (1), 209-217, 2013 | 46 | 2013 |
Bicyclic 1-Hydroxy-2-oxo-1, 2-dihydropyridine-3-carboxamide-Containing HIV-1 Integrase Inhibitors Having High Antiviral Potency against Cells Harboring Raltegravir-Resistant … XZ Zhao, SJ Smith, M Métifiot, BC Johnson, C Marchand, Y Pommier, ... Journal of medicinal chemistry 57 (4), 1573-1582, 2014 | 45 | 2014 |
MK-0536 inhibits HIV-1 integrases resistant to raltegravir M Métifiot, B Johnson, S Smith, XZ Zhao, C Marchand, T Burke, S Hughes, ... Antimicrobial agents and chemotherapy 55 (11), 5127-5133, 2011 | 37 | 2011 |
Mutagenesis of human immunodeficiency virus reverse transcriptase p51 subunit defines residues contributing to vinylogous urea inhibition of ribonuclease H activity S Chung, JT Miller, BC Johnson, SH Hughes, SFJ Le Grice Journal of Biological Chemistry 287 (6), 4066-4075, 2012 | 30 | 2012 |
6, 7-Dihydroxy-1-oxoisoindoline-4-sulfonamide-containing HIV-1 integrase inhibitors XZ Zhao, K Maddali, SJ Smith, M Métifiot, BC Johnson, C Marchand, ... Bioorganic & medicinal chemistry letters 22 (24), 7309-7313, 2012 | 25 | 2012 |
Selectivity for strand-transfer over 3′-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme–DNA interactions in the … M Métifiot, BC Johnson, E Kiselev, L Marler, XZ Zhao, TR Burke, ... Nucleic Acids Research, gkw592, 2016 | 23 | 2016 |
Call Bell Usage: Tracking the Effect of Hourly Staff Rounding. BC Johnson, L Bryant Clinical Journal of Oncology Nursing 24 (3), 328-330, 2020 | 7 | 2020 |
Phase 1 study of Z-endoxifen in patients with advanced gynecologic, desmoid, and hormone receptor-positive solid tumors N Takebe, GOS Coyne, S Kummar, J Collins, JM Reid, R Piekarz, ... Oncotarget 12 (4), 268, 2021 | 6 | 2021 |
Combination therapy with pazopanib and tivantinib modulates VEGF and c-MET levels in refractory advanced solid tumors S Kummar, AK Srivastava, T Navas, F Cecchi, YH Lee, DP Bottaro, ... Investigational new drugs 39 (6), 1577-1586, 2021 | 3 | 2021 |
Isoform-and phosphorylation-specific multiplexed quantitative pharmacodynamics of drugs targeting PI3K and MAPK signaling in xenograft models and clinical biopsies WG Herrick, CL Kilpatrick, MG Hollingshead, D Esposito, GOS Coyne, ... Molecular Cancer Therapeutics 20 (4), 749-760, 2021 | 3 | 2021 |
ROADMAPS: An online database of response data, dosing regimens, and toxicities of approved oncology drugs as single agents to guide preclinical in vivo studies MG Hollingshead, N Greenberg, M Gottholm Ahalt, R Camalier, ... Cancer Research, 2022 | 2 | 2022 |
Compounds for inhibiting drug-resistant strains of HIV-1 integrase XZ Zhao, S Smith, M Metifiot, B Johnson, C Marchand, SH Hughes, ... US Patent 10,208,035, 2019 | 1 | 2019 |
COMPOUNDS FOR INHIBITING DRUG-RESISTANT STRAINS OF HIV-1 INTEGRASE XZ Zhao, S Smith, M Metifiot, B Johnson, C Marchand, SH Hughes, ... US Patent 20,160,083,382, 2016 | 1 | 2016 |
Using data to track staff hourly rounding and its effect on patient call bell usage on an Inpatient Oncology Unit B Johnson, L Bryant ONS 44th Annual Congress, 2019 | | 2019 |