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Florian Heigwer
Florian Heigwer
Professor, University of Applied Sciences Bingen
Verified email at dkfz.de - Homepage
Title
Cited by
Cited by
Year
E-CRISP: fast CRISPR target site identification
F Heigwer, G Kerr, M Boutros
Nature methods 11 (2), 122-123, 2014
9932014
Data-analysis strategies for image-based cell profiling
JC Caicedo, S Cooper, F Heigwer, S Warchal, P Qiu, C Molnar, ...
Nature methods 14 (9), 849-863, 2017
6922017
Microscopy-based high-content screening
M Boutros, F Heigwer, C Laufer
Cell 163 (6), 1314-1325, 2015
4262015
SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB
CJ Neufeldt, B Cerikan, M Cortese, J Frankish, JY Lee, ...
Communications biology 5 (1), 45, 2022
2372022
Machine learning and image-based profiling in drug discovery
C Scheeder, F Heigwer, M Boutros
Current opinion in systems biology 10, 43-52, 2018
1662018
RNA Interference (RNAi) Screening in Drosophila
F Heigwer, F Port, M Boutros
Genetics 208 (3), 853-874, 2018
1662018
A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila
F Port, C Strein, M Stricker, B Rauscher, F Heigwer, J Zhou, ...
Elife 9, e53865, 2020
1392020
CRISPR library designer (CLD): software for multispecies design of single guide RNA libraries
F Heigwer, T Zhan, M Breinig, J Winter, D Brügemann, S Leible, ...
Genome biology 17, 1-10, 2016
902016
GenomeCRISPR-a database for high-throughput CRISPR/Cas9 screens
B Rauscher, F Heigwer, M Breinig, J Winter, M Boutros
Nucleic acids research, gkw997, 2016
862016
E-TALEN: a web tool to design TALENs for genome engineering
F Heigwer, G Kerr, N Walther, K Glaeser, O Pelz, M Breinig, M Boutros
Nucleic acids research 41 (20), e190-e190, 2013
832013
Toward an integrated map of genetic interactions in cancer cells
B Rauscher, F Heigwer, L Henkel, T Hielscher, O Voloshanenko, ...
Molecular Systems Biology 14 (2), 2018
812018
caRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens
J Winter, M Breinig, F Heigwer, D Brügemann, S Leible, O Pelz, T Zhan, ...
Bioinformatics 32 (4), 632-634, 2016
672016
CRISPRAnalyzeR: Interactive analysis, annotation and documentation of pooled CRISPR screens
J Winter, M Schwering, O Pelz, B Rauscher, T Zhan, F Heigwer, M Boutros
BioRxiv, 109967, 2017
532017
Acetic acid treatment in S. cerevisiae creates significant energy deficiency and nutrient starvation that is dependent on the activity of the mitochondrial …
A Kitanovic, F Bonowski, F Heigwer, P Ruoff, I Kitanovic, C Ungewiss, ...
Frontiers in oncology 2, 118, 2012
282012
Time-resolved mapping of genetic interactions to model rewiring of signaling pathways
F Heigwer, C Scheeder, T Miersch, B Schmitt, C Blass, MV Pour Jamnani, ...
Elife 7, e40174, 2018
222018
Enhanced SARS-CoV-2 entry via UPR-dependent AMPK-related kinase NUAK2
V Prasad, B Cerikan, Y Stahl, K Kopp, V Magg, N Acosta-Rivero, H Kim, ...
Molecular Cell 83 (14), 2559-2577. e8, 2023
152023
Microarray‐based kinetic colorimetric detection for quantitative multiplex protein phosphorylation analysis
P Holenya, I Kitanovic, F Heigwer, S Wölfl
Proteomics 11 (10), 2129-2133, 2011
142011
Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice
MC Funk, JG Gleixner, F Heigwer, D Vonficht, E Valentini, Z Aydin, ...
Developmental Cell 58 (24), 2914-2929. e7, 2023
102023
KOMA: ELISA-microarray calibration and data analysis based on kinetic signal amplification
P Holenya, F Heigwer, S Wölfl
Journal of immunological methods 380 (1-2), 10-15, 2012
102012
A global genetic interaction network by single-cell imaging and machine learning
F Heigwer, C Scheeder, J Bageritz, S Yousefian, B Rauscher, C Laufer, ...
Cell Systems 14 (5), 346-362. e6, 2023
62023
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