Kazuhiro A. Fujita
Kazuhiro A. Fujita
The Systems Biology Institute
Bestätigte E-Mail-Adresse bei sbi.jp
Titel
Zitiert von
Zitiert von
Jahr
Prediction and validation of the distinct dynamics of transient and sustained ERK activation
S Sasagawa, Y Ozaki, K Fujita, S Kuroda
Nature Cell Biology 7 (4), 365-373, 2005
5072005
Integrating pathways of Parkinson's disease in a molecular interaction map
KA Fujita, M Ostaszewski, Y Matsuoka, S Ghosh, E Glaab, C Trefois, ...
Molecular Neurobiology 49 (1), 88-102, 2014
2042014
Decoupling of receptor and downstream signals in the akt pathway by its low-pass filter characteristics
KA Fujita, Y Toyoshima, S Uda, Y Ozaki, H Kubota, S Kuroda
Science Signaling 3 (132), ra56, 2010
782010
Sensitivity control through attenuation of signal transfer efficiency by negative regulation of cellular signalling.
Y Toyoshima, H Kakuda, KA Fujita, S Uda, S Kuroda
Nature Communications 3, 743-743, 2012
262012
A mechanism-based simulation model of hepatic toxicity to predict cell death dynamics through mitochondrial dysfunction upon long-term exposure to drug
KA Fujita, A Crudu, A Riu, G Ouedraogo, S Teissier, S Miyabe, I Suzuki, ...
The Journal of Toxicological Sciences 42 (Supplement), S293, 2017
2017
A MECHANISM-BASED SIMULATION MODEL OF HEPATIC TOXICITY TO PREDICT CELL DEATH DYNAMICS THROUGH MITOCHONDRIAL DYSFUNCTION UPON LONG-TERM EXPOSURE TO DRUG
A Riu, A Crudu, KA Fujita, G Ouedraogo, S Teissier, S Miyabe, I Suzuki, ...
The 10th Congress on Alternatives and Animal Use in the Life Sciences, 2017
2017
A mechanism-based hepatotoxicity simulation model to capture dose-dependent cell death dynamics in response to the drugs amiodarone and valproate
A Crudu, R Note, A Riu, G Ouedraogo, O Perin, S Jager, C Gomes, ...
The Society of Toxicology 55th Annual Meeting and ToxExpo, 2016
2016
Weaving Knowledge into Biological Pathways in a Collaborative Manner
Y Matsuoka, K Fujita, S Ghosh, H Kitano
Computational Systems Toxicology, 181-208, 2015
2015
Curation of complex molecular pathways of Parkinson's disease as a collaborative scientific community effort
S Gebel, M Ostaszewski, P Gawron, PMA Antony, C Trefois, KA Fujita, ...
Movement Disorders 29, S11-S12, 2014
2014
Ageing neuron, clean up your room!
KA Fujita
http://minerva.uni.lu/pd_map/index.php/blog-menu/29-ageing-neuron-clean-up, 2014
2014
EGFR inhibitor can serve as a downstream activator in Akt pathway by its low-pass filter characteristics (Japanese title: Akt経路のローパスフィルタ特性によって, EGFR阻害剤が下流の活 …
KA Fujita, Y Toyoshima, S Kuroda
実験医学 29 (1), 65-69, 2011
2011
Frequency Response Analysis of Signal Transduction (Japanese title: 周波数応答を応用したAktシグナル伝達経路のダイナミクスの解析)
KA Fujita, Y Toyoshima, S Kuroda
細胞工学 29 (4), 349-354, 2010
2010
System understanding of ERK signal network: mechanisms for detecting temporal rate and final concentration of growth factors
S Sasagawa, Y Ozaki, K Fujita, S Kuroda
Protein, nucleic acid and enzyme 50 (16 Suppl), 2275-2281, 2005
2005
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