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| Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS E Storkebaum, D Lambrechts, M Dewerchin, MP Moreno-Murciano, ... Nature neuroscience 8 (1), 85-92, 2005 | 604 | 2005 |
| Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility International Multiple Sclerosis Genetics Consortium*†, ANZgene, ... Science 365 (6460), eaav7188, 2019 | 548 | 2019 |
| The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis L Van Den Bosch, P Van Damme, E Bogaert, W Robberecht Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (11-12 …, 2006 | 532 | 2006 |
| Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 496 | 2016 |
| HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease C d'Ydewalle, J Krishnan, DM Chiheb, P Van Damme, J Irobi, ... Nature medicine 17 (8), 968-974, 2011 | 495 | 2011 |
| Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ... Neuron 90 (3), 535-550, 2016 | 477 | 2016 |
| Genome-wide analyses identify KIF5A as a novel ALS gene A Nicolas, KP Kenna, AE Renton, N Ticozzi, F Faghri, R Chia, ... Neuron 97 (6), 1268-1283. e6, 2018 | 445 | 2018 |
| Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ... Molecular cell 65 (6), 1044-1055. e5, 2017 | 422 | 2017 |
| Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival P Van Damme, A Van Hoecke, D Lambrechts, P Vanacker, E Bogaert, ... The Journal of cell biology 181 (1), 37-41, 2008 | 419 | 2008 |
| Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind … JF Howard, K Utsugisawa, M Benatar, H Murai, RJ Barohn, I Illa, S Jacob, ... The Lancet Neurology 16 (12), 976-986, 2017 | 409 | 2017 |
| Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model HJ Westeneng, TPA Debray, AE Visser, RPA van Eijk, JPK Rooney, ... The Lancet Neurology 17 (5), 423-433, 2018 | 316 | 2018 |
| EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans A Van Hoecke, L Schoonaert, R Lemmens, M Timmers, KA Staats, ... Nature medicine 18 (9), 1418-1422, 2012 | 314 | 2012 |
| Amyotrophic lateral sclerosis: a clinical review P Masrori, P Van Damme European journal of neurology 27 (10), 1918-1929, 2020 | 305 | 2020 |
| Phase 1–2 Trial of Antisense Oligonucleotide Tofersen for SOD1 ALS T Miller, M Cudkowicz, PJ Shaw, PM Andersen, N Atassi, RC Bucelli, ... New England Journal of Medicine 383 (2), 109-119, 2020 | 289 | 2020 |
| Chromosome 9p21 in sporadic amyotrophic lateral sclerosis in the UK and seven other countries: a genome-wide association study A Shatunov, K Mok, S Newhouse, ME Weale, B Smith, C Vance, ... The Lancet Neurology 9 (10), 986-994, 2010 | 259 | 2010 |
| HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients W Guo, M Naujock, L Fumagalli, T Vandoorne, P Baatsen, R Boon, ... Nature communications 8 (1), 861, 2017 | 256 | 2017 |
| Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity P Van Damme, E Bogaert, M Dewil, N Hersmus, D Kiraly, W Scheveneels, ... Proceedings of the National Academy of Sciences 104 (37), 14825-14830, 2007 | 252 | 2007 |
| Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD S Boeynaems, E Bogaert, E Michiels, I Gijselinck, A Sieben, A Jovičić, ... Scientific reports 6 (1), 20877, 2016 | 247 | 2016 |
| Treatment-related peripheral neuropathy in multiple myeloma: the challenge continues M Delforge, J Bladé, MA Dimopoulos, T Facon, M Kropff, H Ludwig, ... The lancet oncology 11 (11), 1086-1095, 2010 | 247 | 2010 |
Ludo Van Den BoschKU Leuven & VIBVerified email at kuleuven.vib.be
