| ApoE facilitates the microglial response to amyloid plaque pathology JD Ulrich, TK Ulland, TE Mahan, S Nyström, KP Nilsson, WM Song, ... Journal of Experimental Medicine 215 (4), 1047-1058, 2018 | 227 | 2018 |
| Imaging distinct conformational states of amyloid-β fibrils in Alzheimer’s disease using novel luminescent probes KPR Nilsson, A Åslund, I Berg, S Nyström, P Konradsson, A Herland, ... ACS chemical biology 2 (8), 553-560, 2007 | 217 | 2007 |
| Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates T Klingstedt, A Åslund, RA Simon, LBG Johansson, JJ Mason, S Nyström, ... Organic & biomolecular chemistry 9 (24), 8356-8370, 2011 | 213 | 2011 |
| Lysozyme amyloidogenesis is accelerated by specific nicking and fragmentation but decelerated by intact protein binding and conversion R Mishra, K Sörgjerd, S Nyström, A Nordigården, YC Yu, P Hammarström Journal of molecular biology 366 (3), 1029-1044, 2007 | 209 | 2007 |
| Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease J Rasmussen, J Mahler, N Beschorner, SA Kaeser, LM Häsler, ... Proceedings of the National Academy of Sciences 114 (49), 13018-13023, 2017 | 205 | 2017 |
| Structure-based drug design identifies polythiophenes as antiprion compounds US Herrmann, AK Schütz, H Shirani, D Huang, D Saban, M Nuvolone, ... Science translational medicine 7 (299), 299ra123-299ra123, 2015 | 138 | 2015 |
| Amyloid fibril polymorphism: a challenge for molecular imaging and therapy M Fändrich, S Nyström, KPR Nilsson, A Böckmann, H LeVine III, ... Journal of Internal Medicine 283 (3), 218-237, 2018 | 130 | 2018 |
| Evidence for Age-Dependent in Vivo Conformational Rearrangement within Aβ Amyloid Deposits S Nyström, KM Psonka-Antonczyk, PG Ellingsen, LBG Johansson, ... ACS chemical biology 8 (6), 1128-1133, 2013 | 120 | 2013 |
| A fluorescent pentameric thiophene derivative detects in vitro-formed prefibrillar protein aggregates P Hammarstrom, R Simon, S Nystrom, P Konradsson, A Åslund, ... Biochemistry 49 (32), 6838-6845, 2010 | 115 | 2010 |
| Amyloidogenesis of SARS-CoV-2 spike protein S Nystrom, P Hammarstrom Journal of the American Chemical Society 144 (20), 8945-8950, 2022 | 108 | 2022 |
| Polythiophenes inhibit prion propagation by stabilizing prion protein (PrP) aggregates I Margalith, C Suter, B Ballmer, P Schwarz, C Tiberi, T Sonati, J Falsig, ... Journal of Biological Chemistry 287 (23), 18872-18887, 2012 | 79 | 2012 |
| De novo design of a biologically active amyloid R Gallardo, M Ramakers, F De Smet, F Claes, L Khodaparast, ... Science 354 (6313), aah4949, 2016 | 71 | 2016 |
| Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1–40 deposition underlies plaque polymorphism in progressing Alzheimer’s disease pathology W Michno, S Nyström, P Wehrli, T Lashley, G Brinkmalm, L Guerard, ... Journal of Biological Chemistry 294 (17), 6719-6732, 2019 | 65 | 2019 |
| Distinct spacing between anionic groups: an essential chemical determinant for achieving Thiophene‐based ligands to distinguish β‐amyloid or tau polymorphic aggregates T Klingstedt, H Shirani, J Mahler, BM Wegenast‐Braun, S Nyström, ... Chemistry–A European Journal 21 (25), 9072-9082, 2015 | 56 | 2015 |
| S100A9-driven amyloid-neuroinflammatory cascade in traumatic brain injury as a precursor state for Alzheimer’s disease C Wang, IA Iashchishyn, J Pansieri, S Nyström, O Klementieva, J Kara, ... Scientific Reports 8 (1), 12836, 2018 | 50 | 2018 |
| Synthesis and evaluation of benzothiazole-triazole and benzothiadiazole-triazole scaffolds as potential molecular probes for amyloid-β aggregation C Dyrager, RP Vieira, S Nyström, KPR Nilsson, T Storr New Journal of Chemistry 41 (4), 1566-1573, 2017 | 48 | 2017 |
| Multimodal chemical imaging of amyloid plaque polymorphism reveals Aβ aggregation dependent anionic lipid accumulations and metabolism W Michno, I Kaya, S Nyström, L Guerard, KPR Nilsson, ... Analytical chemistry 90 (13), 8130-8138, 2018 | 43 | 2018 |
| Amyloid fibrils of human prion protein are spun and woven from morphologically disordered aggregates K Almstedt, S Nyström, KPR Nilsson, P Hammarström Prion 3 (4), 224-235, 2009 | 43 | 2009 |
| Amyloid Beta1-40-Induced Astrogliosis and the Effect of Genistein Treatment in Rat: A Three-Dimensional Confocal Morphometric and Proteomic Study M Bagheri, A Rezakhani, S Nyström, MV Turkina, M Roghani, ... PLoS One 8 (10), e76526, 2013 | 39 | 2013 |
| Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease AM Sevillano, P Aguilar-Calvo, TD Kurt, JA Lawrence, K Soldau, TH Nam, ... The Journal of clinical investigation 130 (3), 1350-1362, 2020 | 38 | 2020 |
