| Role of tumor–host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors A Pluen, Y Boucher, S Ramanujan, TD McKee, T Gohongi, E Di Tomaso, ... Proceedings of the National Academy of Sciences 98 (8), 4628-4633, 2001 | 732 | 2001 |
| Diffusion and convection in collagen gels: implications for transport in the tumor interstitium S Ramanujan, A Pluen, TD McKee, EB Brown, Y Boucher, RK Jain Biophysical journal 83 (3), 1650-1660, 2002 | 634 | 2002 |
| Deformation of liquid capsules enclosed by elastic membranes in simple shear flow: large deformations and the effect of fluid viscosities S Ramanujan, C Pozrikidis Journal of fluid mechanics 361, 117-143, 1998 | 478 | 1998 |
| A comprehensive review of interventions in the NOD mouse and implications for translation LKM Shoda, DL Young, S Ramanujan, CC Whiting, MA Atkinson, ... Immunity 23 (2), 115-126, 2005 | 365 | 2005 |
| Apparatus and method for computer modeling type 1 diabetes K Gadkar, H Kreuwel, T Paterson, D Polidori, S Ramanujan, LKM Shoda, ... US Patent App. 11/377,614, 2007 | 324 | 2007 |
| Validation of a novel multibiomarker test to assess rheumatoid arthritis disease activity JR Curtis, AH van der Helm‐van Mil, R Knevel, TW Huizinga, DJ Haney, ... Arthritis care & research 64 (12), 1794-1803, 2012 | 222 | 2012 |
| Development of a multi-biomarker disease activity test for rheumatoid arthritis M Centola, G Cavet, Y Shen, S Ramanujan, N Knowlton, KA Swan, ... PloS one 8 (4), e60635, 2013 | 212 | 2013 |
| Local imbalance of proangiogenic and antiangiogenic factors: a potential mechanism of focal necrosis and dormancy in tumors S Ramanujan, GC Koenig, TP Padera, BR Stoll, RK Jain Cancer research 60 (5), 1442-1448, 2000 | 143 | 2000 |
| A transcriptional MAPK Pathway Activity Score (MPAS) is a clinically relevant biomarker in multiple cancer types MC Wagle, D Kirouac, C Klijn, B Liu, S Mahajan, M Junttila, J Moffat, ... NPJ precision oncology 2 (1), 7, 2018 | 134 | 2018 |
| Solid stress facilitates spheroid formation: potential involvement of hyaluronan C Koike, TD McKee, A Pluen, S Ramanujan, K Burton, LL Munn, ... British journal of cancer 86 (6), 947-953, 2002 | 99 | 2002 |
| A six‐stage workflow for robust application of systems pharmacology K Gadkar, DC Kirouac, DE Mager, PH van der Graaf, S Ramanujan CPT: pharmacometrics & systems pharmacology 5 (5), 235-249, 2016 | 81 | 2016 |
| Differential Dynamics of CD4+ and CD8+ T-Lymphocyte Proliferation and Activation in Acute Simian Immunodeficiency Virus Infection A Kaur, CL Hale, S Ramanujan, RK Jain, RP Johnson Journal of virology 74 (18), 8413-8424, 2000 | 79 | 2000 |
| Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling I Hosseini, K Gadkar, E Stefanich, CC Li, LL Sun, YW Chu, S Ramanujan NPJ systems biology and applications 6 (1), 28, 2020 | 75 | 2020 |
| Method and apparatus for computer modeling a joint NA Defranoux, TB Dubnicoff, IIDJ Klinke, AK Lewis, TS Paterson, ... US Patent 7,472,050, 2008 | 61 | 2008 |
| Clinical responses to ERK inhibition in BRAFV600E-mutant colorectal cancer predicted using a computational model DC Kirouac, G Schaefer, J Chan, M Merchant, C Orr, SMA Huang, J Moffat, ... NPJ systems biology and applications 3 (1), 14, 2017 | 60 | 2017 |
| The Type 1 Diabetes PhysioLab® Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse L Shoda, H Kreuwel, K Gadkar, Y Zheng, C Whiting, M Atkinson, ... Clinical & Experimental Immunology 161 (2), 250-267, 2010 | 55 | 2010 |
| Quantitative systems pharmacology: a case for disease models CJ Musante, S Ramanujan, BJ Schmidt, OG Ghobrial, J Lu, ... Clinical Pharmacology & Therapeutics 101 (1), 24-27, 2017 | 54 | 2017 |
| Systems biology for battling rheumatoid arthritis: application of the Entelos PhysioLab platform JAC Rullmann, H Struemper, NA Defranoux, S Ramanujan, ... IEE Proceedings-Systems Biology 152 (4), 256-262, 2005 | 54 | 2005 |
| Mechanism-based pharmacokinetic/pharmacodynamic model for THIOMAB™ drug conjugates S Sukumaran, K Gadkar, C Zhang, S Bhakta, L Liu, K Xu, H Raab, SF Yu, ... Pharmaceutical research 32, 1884-1893, 2015 | 51 | 2015 |
| Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain K Gadkar, DB Yadav, JY Zuchero, JA Couch, J Kanodia, MK Kenrick, ... European Journal of Pharmaceutics and Biopharmaceutics 101, 53-61, 2016 | 49 | 2016 |
