| DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells T Gu, X Lin, SM Cullen, M Luo, M Jeong, M Estecio, J Shen, S Hardikar, ... Genome biology 19, 1-15, 2018 | 152 | 2018 |
| UNC2025, a Potent and Orally Bioavailable MER/FLT3 Dual Inhibitor W Zhang, D DeRyckere, D Hunter, J Liu, MA Stashko, KA Minson, ... Journal of medicinal chemistry 57 (16), 7031-7041, 2014 | 145 | 2014 |
| Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis S Zang, J Li, H Yang, H Zeng, W Han, J Zhang, M Lee, M Moczygemba, ... The Journal of clinical investigation 127 (8), 2998-3012, 2017 | 81 | 2017 |
| Pseudo-cyclization through intramolecular hydrogen bond enables discovery of pyridine substituted pyrimidines as new Mer kinase inhibitors W Zhang, D Zhang, MA Stashko, D DeRyckere, D Hunter, D Kireev, ... Journal of medicinal chemistry 56 (23), 9683-9692, 2013 | 81 | 2013 |
| Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosis W Zhang, AL McIver, MA Stashko, D DeRyckere, BR Branchford, D Hunter, ... Journal of medicinal chemistry 56 (23), 9693-9700, 2013 | 66 | 2013 |
| Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC J Li, X Wu, Y Zhou, M Lee, L Guo, W Han, W Mo, W Cao, D Sun, R Xie, ... Nucleic acids research 46 (6), 2883-2900, 2018 | 65 | 2018 |
| Drosophila DJ-1 Decreases Neural Sensitivity to Stress by Negatively Regulating Daxx-Like Protein through dFOXO S Hwang, S Song, YK Hong, G Choi, YS Suh, SY Han, M Lee, SH Park, ... PLoS genetics 9 (4), e1003412, 2013 | 61 | 2013 |
| Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma J Li, S Zhao, M Lee, Y Yin, J Li, Y Zhou, LY Ballester, Y Esquenazi, ... Science advances 6 (42), eabb5427, 2020 | 60 | 2020 |
| Tet inactivation disrupts YY1 binding and long-range chromatin interactions during embryonic heart development S Fang, J Li, Y Xiao, M Lee, L Guo, W Han, T Li, MC Hill, T Hong, W Mo, ... Nature communications 10 (1), 4297, 2019 | 58 | 2019 |
| Neuroprotective effect of SuHeXiang Wan in Drosophila models of Alzheimer's disease YK Hong, SH Park, S Lee, S Hwang, MJ Lee, D Kim, JH Lee, SY Han, ... Journal of ethnopharmacology 134 (3), 1028-1032, 2011 | 55 | 2011 |
| The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia MJ Lee, SH Park, JH Han, YK Hong, S Hwang, S Lee, D Kim, SY Han, ... Molecules and cells 31 (4), 337-342, 2011 | 50 | 2011 |
| ZRANB1 is an EZH2 deubiquitinase and a potential therapeutic target in breast cancer P Zhang, Z Xiao, S Wang, M Zhang, Y Wei, Q Hang, J Kim, F Yao, ... Cell reports 23 (3), 823-837, 2018 | 44 | 2018 |
| Saeng-Maek-San, a medicinal herb complex, protects liver cell damage induced by alcohol KJ Park, MJ Lee, H Kang, KS Kim, SH Lee, I Cho, HH Lee Biological and Pharmaceutical Bulletin 25 (11), 1451-1455, 2002 | 39 | 2002 |
| Parkin Suppresses c-Jun N-terminal kinase-induced cell death via transriptional regulation in Drosophila S Hwang, D Kim, G Choi, SW An, YK Hong, YS Suh, MJ Lee, KS Cho Molecules and cells 29 (6), 575-580, 2010 | 38 | 2010 |
| A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells L Guo, J Li, H Zeng, AG Guzman, T Li, M Lee, Y Zhou, MA Goodell, ... Nature communications 11 (1), 740, 2020 | 34 | 2020 |
| Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor YH Huang, CW Chen, V Sundaramurthy, M Słabicki, D Hao, CJ Watson, ... Cancer discovery 12 (1), 220-235, 2022 | 33 | 2022 |
| Altered chromatin states drive cryptic transcription in aging mammalian stem cells BS McCauley, L Sun, R Yu, M Lee, H Liu, DS Leeman, Y Huang, ... Nature aging 1 (8), 684-697, 2021 | 31 | 2021 |
| Tet2 inactivation enhances the antitumor activity of tumor-infiltrating lymphocytes M Lee, J Li, J Li, S Fang, J Zhang, ATT Vo, W Han, H Zeng, S Isgandarova, ... Cancer research 81 (8), 1965-1976, 2021 | 30 | 2021 |
| Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies H Zeng, H He, L Guo, J Li, M Lee, W Han, AG Guzman, S Zang, Y Zhou, ... Cancer letters 467, 1-8, 2019 | 28 | 2019 |
| Engineered split-TET2 enzyme for inducible epigenetic remodeling M Lee, J Li, Y Liang, G Ma, J Zhang, L He, Y Liu, Q Li, M Li, D Sun, Y Zhou, ... Journal of the American Chemical Society 139 (13), 4659-4662, 2017 | 22 | 2017 |
