Follow
Eric S. Wang
Eric S. Wang
Sanford Burnham Prebys Medical Discovery Institute
Verified email at sbpdiscovery.org
Title
Cited by
Cited by
Year
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2
JP Upton, L Wang, D Han, ES Wang, NE Huskey, L Lim, M Truitt, ...
Science 338 (6108), 818-822, 2012
7092012
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
Cancer discovery 8 (2), 216-233, 2018
5812018
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress
R Ghosh, L Wang, ES Wang, BGK Perera, A Igbaria, S Morita, K Prado, ...
Cell 158 (3), 534-548, 2014
4702014
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ...
Cancer discovery 8 (2), 196-215, 2018
4342018
Development of dual and selective degraders of cyclin‐dependent kinases 4 and 6
B Jiang, ES Wang, KA Donovan, Y Liang, ES Fischer, T Zhang, NS Gray
Angewandte Chemie International Edition 58 (19), 6321-6326, 2019
2052019
Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML
M Brand, B Jiang, S Bauer, KA Donovan, Y Liang, ES Wang, RP Nowak, ...
Cell chemical biology 26 (2), 300-306. e9, 2019
2012019
CDK7 inhibition potentiates genome instability triggering anti-tumor immunity in small cell lung cancer
H Zhang, CL Christensen, R Dries, MG Oser, J Deng, B Diskin, F Li, Y Pan, ...
Cancer cell 37 (1), 37-54. e9, 2020
1672020
Bruton tyrosine kinase degradation as a therapeutic strategy for cancer
D Dobrovolsky, ES Wang, S Morrow, C Leahy, T Faust, RP Nowak, ...
Blood, The Journal of the American Society of Hematology 133 (9), 952-961, 2019
1432019
Development of highly potent and selective steroidal inhibitors and degraders of CDK8
JM Hatcher, ES Wang, L Johannessen, N Kwiatkowski, T Sim, NS Gray
ACS medicinal chemistry letters 9 (6), 540-545, 2018
852018
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer
J Deng, A Thennavan, I Dolgalev, T Chen, J Li, A Marzio, JT Poirier, ...
Nature cancer 2 (5), 503-514, 2021
762021
Inhibition of CDK4/6 promotes CD8 T-cell memory formation
M Heckler, LR Ali, E Clancy-Thompson, L Qiang, KS Ventre, P Lenehan, ...
Cancer discovery 11 (10), 2564-2581, 2021
712021
Acute pharmacological degradation of Helios destabilizes regulatory T cells
ES Wang, AL Verano, RP Nowak, JC Yuan, KA Donovan, NA Eleuteri, ...
Nature chemical biology 17 (6), 711-717, 2021
592021
Selective degradation of GSPT1 by cereblon modulators identified via a focused combinatorial library
CE Powell, G Du, J Che, Z He, KA Donovan, H Yue, ES Wang, RP Nowak, ...
ACS chemical biology 15 (10), 2722-2730, 2020
582020
Fas-activated mitochondrial apoptosis culls stalled embryonic stem cells to promote differentiation
ES Wang, NA Reyes, C Melton, NE Huskey, O Momcilovic, A Goga, ...
Current Biology 25 (23), 3110-3118, 2015
232015
Reexamination of the cysteine residues in glucocerebrosidase
R Moharram, D Maynard, ES Wang, A Makusky, GJ Murray, BM Martin
FEBS letters 580 (14), 3391-3394, 2006
102006
Development of highly potent and selective pyrazolopyridine inhibitor of CDK8/19
JM Hatcher, PS Vatsan, E Wang, J Jiang, NS Gray
ACS Medicinal Chemistry Letters 12 (11), 1689-1693, 2021
82021
Degradation of cyclin-dependent kinase 4/6 (CDK4/6) by conjugation of CDK4/6 inhibitors with E3 ligase ligand and methods of use
NS Gray, T Zhang, CM Olson, Y Liang, N Kwiatkowski, B Jiang, E Wang
US Patent 10,865,204, 2020
82020
PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
JL Hope, DC Otero, EA Bae, CJ Stairiker, AB Palete, HA Faso, M Lin, ...
Cell reports 42 (5), 2023
72023
Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferation
I You, KA Donovan, NM Krupnick, AS Boghossian, MG Rees, MM Ronan, ...
Cell chemical biology 29 (11), 1630-1638. e7, 2022
72022
Development of potent and selective degraders of PI5P4Kγ
W Ji, ES Wang, TD Manz, J Jiang, KA Donovan, X Abulaiti, ES Fischer, ...
European Journal of Medicinal Chemistry 247, 115027, 2023
52023
The system can't perform the operation now. Try again later.
Articles 1–20