The role of apolipoprotein E in Alzheimer's disease J Kim, JM Basak, DM Holtzman Neuron 63 (3), 287-303, 2009 | 1905 | 2009 |
Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular Aβ clearance J Kim, JM Castellano, H Jiang, JM Basak, M Parsadanian, V Pham, ... Neuron 64 (5), 632-644, 2009 | 280 | 2009 |
Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes JM Basak, PB Verghese, H Yoon, J Kim, DM Holtzman Journal of Biological Chemistry 287 (17), 13959-13971, 2012 | 212 | 2012 |
Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis J Kim, H Jiang, S Park, AEM Eltorai, FR Stewart, H Yoon, JM Basak, ... Journal of Neuroscience 31 (49), 18007-18012, 2011 | 203 | 2011 |
Apolipoprotein E in synaptic plasticity and Alzheimer’s disease: potential cellular and molecular mechanisms J Kim, H Yoon, J Basak, J Kim Molecules and cells 37 (11), 767-776, 2014 | 151 | 2014 |
Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis J Kim, AEM Eltorai, H Jiang, F Liao, PB Verghese, J Kim, FR Stewart, ... Journal of Experimental Medicine 209 (12), 2149-2156, 2012 | 148 | 2012 |
Contribution of reactive oxygen species to cerebral amyloid angiopathy, vasomotor dysfunction, and microhemorrhage in aged Tg2576 mice BH Han, M Zhou, AW Johnson, I Singh, F Liao, AK Vellimana, JW Nelson, ... Proceedings of the National Academy of Sciences 112 (8), E881-E890, 2015 | 145 | 2015 |
The low density lipoprotein receptor-related protein 1 mediates uptake of amyloid β peptides in an in vitro model of the blood-brain barrier cells K Yamada, T Hashimoto, C Yabuki, Y Nagae, M Tachikawa, DK Strickland, ... Journal of biological chemistry 283 (50), 34554-34562, 2008 | 138 | 2008 |
Bi-compartmental communication contributes to the opposite proliferative behavior of Notch1-deficient hair follicle and epidermal keratinocytes J Lee, JM Basak, S Demehri, R Kopan Oxford University Press for The Company of Biologists Limited 134 (15), 2795 …, 2007 | 85 | 2007 |
In vivo human apolipoprotein E isoform fractional turnover rates in the CNS KR Wildsmith, JM Basak, BW Patterson, Y Pyatkivskyy, J Kim, ... PloS one 7 (6), e38013, 2012 | 56 | 2012 |
Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling JM Basak, J Kim, Y Pyatkivskyy, KR Wildsmith, H Jiang, M Parsadanian, ... Molecular neurodegeneration 7, 1-13, 2012 | 30 | 2012 |
Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer's disease JM Basak, A Ferreiro, LS Cohen, PW Sheehan, CJ Nadarajah, MF Kanan, ... Neurobiology of disease 152, 105292, 2021 | 28 | 2021 |
Differential effects of ApoE isoforms on dendritic spines in vivo: linking an Alzheimer's disease risk factor with synaptic alterations JM Basak, J Kim Journal of Neuroscience 30 (13), 4526-4527, 2010 | 5 | 2010 |
Targeting BACE1-mediated production of amyloid beta improves hippocampal synaptic function in an experimental model of ischemic stroke JM Basak, M Falk, DN Mitchell, KA Coakley, N Quillinan, JE Orfila, ... Journal of Cerebral Blood Flow & Metabolism 43 (2_suppl), 66-77, 2023 | 3 | 2023 |
APP-based transgenic models: the PDAPP model JM Basak, DM Holtzman Animal models of dementia, 371-385, 2011 | 2 | 2011 |
193: A CASE OF SUSPECTED COVID-19 REACTIVATION IN A KIDNEY TRANSPLANT RECIPIENT B Primi, J Basak Critical Care Medicine 50 (1), 80, 2022 | 1 | 2022 |
MCAo stroke increases hippocampal soluble amyloid beta production in a TRPM2-dependent manner J Basak, M Falk, D Mitchell, B Wassermann, N Quillinan, P Herson JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM 42 (1_ SUPPL), 14-14, 2022 | | 2022 |
The Role of an Amyloid Beta-TRPM2 Interaction in Causing Post-Stroke Cognitive Impairment and Synaptic Dysfunction J Basak, JE Orfila, M Falk, RM Dietz, A Burch, D Mitchell, B Wassermann, ... ANESTHESIA AND ANALGESIA 132 (5 S_ SUPPL), 385-385, 2021 | | 2021 |
Abstract P765: Therapeutic Approaches to Reduce Post-Stroke Cognitive Impairment JM Basak, JE Orfila, R Dietz, A Burch, A Dingman, D Mitchell, ... Stroke 52 (Suppl_1), AP765-AP765, 2021 | | 2021 |
BACTERIAL SEPSIS INCREASES FIBRILLARY AMYLOID LOAD AND NEUROINFLAMMATION IN A MOUSE MODEL OF ALZHEIMER'S DISEASE PATHOLOGY J Basak, CJ Nadarajah, LS Cohen, PW Sheehan, ES Musiek ANESTHESIA AND ANALGESIA 128, 185-185, 2019 | | 2019 |