Christof von Kalle
Christof von Kalle
CRO SIDRA, Doha, Qatar, Head of Department, German Cancer Center, Heidelberg, Germany
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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
S Hacein-Bey-Abina, C Von Kalle, M Schmidt, MP McCormack, ...
science 302 (5644), 415-419, 2003
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
S Hacein-Bey-Abina, C Von Kalle, M Schmidt, F Le Deist, N Wulffraat, ...
New England journal of medicine 348 (3), 255-256, 2003
International network of cancer genome projects
International Cancer Genome Consortium
Nature 464 (7291), 993, 2010
Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
N Cartier, S Hacein-Bey-Abina, CC Bartholomae, G Veres, M Schmidt, ...
science 326 (5954), 818-823, 2009
Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1
MG Ott, M Schmidt, K Schwarzwaelder, S Stein, U Siler, U Koehl, H Glimm, ...
Nature medicine 12 (4), 401-409, 2006
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients
SJ Howe, MR Mansour, K Schwarzwaelder, C Bartholomae, M Hubank, ...
The Journal of clinical investigation 118 (9), 2008
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy
A Biffi, E Montini, L Lorioli, M Cesani, F Fumagalli, T Plati, C Baldoli, ...
Science 341 (6148), 2013
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome
A Aiuti, L Biasco, S Scaramuzza, F Ferrua, MP Cicalese, C Baricordi, ...
Science 341 (6148), 2013
Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration
E Montini, D Cesana, M Schmidt, F Sanvito, M Ponzoni, C Bartholomae, ...
Nature biotechnology 24 (6), 687-696, 2006
Dissecting the genomic complexity underlying medulloblastoma
DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ...
Nature 488 (7409), 100-105, 2012
Murine leukemia induced by retroviral gene marking
Z Li, J Dullmann, B Schiedlmeier, M Schmidt, C Von Kalle, J Meyer, ...
Science 296 (5567), 497-497, 2002
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease
S Stein, MG Ott, S Schultze-Strasser, A Jauch, B Burwinkel, A Kinner, ...
Nature medicine 16 (2), 198-204, 2010
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector
HB Gaspar, KL Parsley, S Howe, D King, KC Gilmour, J Sinclair, G Brouns, ...
The Lancet 364 (9452), 2181-2187, 2004
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ...
Nature genetics 45 (8), 927-932, 2013
An unbiased genome-wide analysis of zinc-finger nuclease specificity
R Gabriel, A Lombardo, A Arens, JC Miller, P Genovese, C Kaeppel, ...
Nature biotechnology 29 (9), 816-823, 2011
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition
M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ...
Cancer cell 25 (3), 393-405, 2014
The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy
E Montini, D Cesana, M Schmidt, F Sanvito, CC Bartholomae, M Ranzani, ...
The Journal of clinical investigation 119 (4), 964-975, 2009
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
Stem-cell gene therapy for the Wiskott–Aldrich syndrome
K Boztug, M Schmidt, A Schwarzer, PP Banerjee, IA Díez, RA Dewey, ...
New England Journal of Medicine 363 (20), 1918-1927, 2010
Effective gene therapy with nonintegrating lentiviral vectors
RJ Yánez-Munoz, KS Balaggan, A MacNeil, SJ Howe, M Schmidt, ...
Nature medicine 12 (3), 348-353, 2006
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