| PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis W Yang, Y Xia, D Hawke, X Li, J Liang, D Xing, K Aldape, T Hunter, ... Cell 150 (4), 685-696, 2012 | 799 | 2012 |
| Mitochondria-translocated PGK1 functions as a protein kinase to coordinate glycolysis and the TCA cycle in tumorigenesis X Li, Y Jiang, J Meisenhelder, W Yang, DH Hawke, Y Zheng, Y Xia, ... Molecular cell 61 (5), 705-719, 2016 | 381 | 2016 |
| KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase Y Wang, YR Guo, K Liu, Z Yin, R Liu, Y Xia, L Tan, P Yang, JH Lee, X Li, ... Nature 552 (7684), 273-277, 2017 | 355 | 2017 |
| Regulation of chromatin and gene expression by metabolic enzymes and metabolites X Li, G Egervari, Y Wang, SL Berger, Z Lu Nature reviews Molecular cell biology 19 (9), 563-578, 2018 | 338 | 2018 |
| Nucleus-translocated ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy X Li, W Yu, X Qian, Y Xia, Y Zheng, JH Lee, W Li, J Lyu, G Rao, X Zhang, ... Molecular cell 66 (5), 684-697. e9, 2017 | 259 | 2017 |
| PKM2 regulates chromosome segregation and mitosis progression of tumor cells Y Jiang, X Li, W Yang, DH Hawke, Y Zheng, Y Xia, K Aldape, C Wei, ... Molecular cell 53 (1), 75-87, 2014 | 249 | 2014 |
| Phosphoglycerate kinase 1 phosphorylates Beclin1 to induce autophagy XU Qian, X Li, Q Cai, C Zhang, Q Yu, Y Jiang, JH Lee, D Hawke, Y Wang, ... Molecular cell 65 (5), 917-931. e6, 2017 | 229 | 2017 |
| The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis D Xu, Z Wang, Y Xia, F Shao, W Xia, Y Wei, X Li, XU Qian, JH Lee, L Du, ... Nature 580 (7804), 530-535, 2020 | 194 | 2020 |
| Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation Y Jiang, X Qian, J Shen, Y Wang, X Li, R Liu, Y Xia, Q Chen, G Peng, ... Nature cell biology 17 (9), 1158-1168, 2015 | 180 | 2015 |
| Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis XJ Li, CK Ong, Y Cao, YQ Xiang, JY Shao, A Ooi, LX Peng, WH Lu, ... Cancer research 71 (8), 3162-3172, 2011 | 158 | 2011 |
| PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis J Liang, R Cao, Y Zhang, Y Xia, Y Zheng, X Li, L Wang, W Yang, Z Lu Nature communications 7 (1), 12431, 2016 | 155 | 2016 |
| A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation X Li, X Qian, LX Peng, Y Jiang, DH Hawke, Y Zheng, Y Xia, JH Lee, ... Nature cell biology 18 (5), 561-571, 2016 | 152 | 2016 |
| PTEN suppresses glycolysis by dephosphorylating and inhibiting autophosphorylated PGK1 X Qian, X Li, Z Shi, Y Xia, Q Cai, D Xu, L Tan, L Du, Y Zheng, D Zhao, ... Molecular Cell 76 (3), 516-527. e7, 2019 | 140 | 2019 |
| As an independent unfavorable prognostic factor, IL-8 promotes metastasis of nasopharyngeal carcinoma through induction of epithelial–mesenchymal transition and activation of … XJ Li, LX Peng, JY Shao, WH Lu, JX Zhang, S Chen, ZY Chen, YQ Xiang, ... Carcinogenesis 33 (7), 1302-1309, 2012 | 139 | 2012 |
| EGFR-phosphorylated platelet isoform of phosphofructokinase 1 promotes PI3K activation JH Lee, R Liu, J Li, Y Wang, L Tan, XJ Li, X Qian, C Zhang, Y Xia, D Xu, ... Molecular cell 70 (2), 197-210. e7, 2018 | 133 | 2018 |
| β-Catenin induces transcriptional expression of PD-L1 to promote glioblastoma immune evasion L Du, JH Lee, H Jiang, C Wang, S Wang, Z Zheng, F Shao, D Xu, Y Xia, ... Journal of Experimental Medicine 217 (11), e20191115, 2020 | 128 | 2020 |
| PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells Y Jiang, Y Wang, T Wang, DH Hawke, Y Zheng, X Li, Q Zhou, S Majumder, ... Nature communications 5 (1), 1-14, 2014 | 124 | 2014 |
| Programmable base editing of mutated TERT promoter inhibits brain tumour growth X Li, X Qian, B Wang, Y Xia, Y Zheng, L Du, D Xu, D Xing, RA DePinho, ... Nature cell biology 22 (3), 282-288, 2020 | 115 | 2020 |
| KDM3A senses oxygen availability to regulate PGC-1α-mediated mitochondrial biogenesis X Qian, X Li, Z Shi, X Bai, Y Xia, Y Zheng, D Xu, F Chen, Y You, J Fang, ... Molecular cell 76 (6), 885-895. e7, 2019 | 100 | 2019 |
| DHHC9-mediated GLUT1 S-palmitoylation promotes glioblastoma glycolysis and tumorigenesis Z Zhang, X Li, F Yang, C Chen, P Liu, Y Ren, P Sun, Z Wang, Y You, ... Nature communications 12 (1), 5872, 2021 | 93 | 2021 |
Zhimin LuZhejiang University, MD Anderson Cancer CenterVerified email at zju.edu.cn
