Nonsense-mediated mRNA decay—mechanisms of substrate mRNA recognition and degradation in mammalian cells C Schweingruber, SC Rufener, D Zünd, A Yamashita, O Mühlemann Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (6-7 …, 2013 | 385 | 2013 |
The host nonsense-mediated mRNA decay pathway restricts mammalian RNA virus replication G Balistreri, P Horvath, C Schweingruber, D Zünd, G McInerney, A Merits, ... Cell host & microbe 16 (3), 403-411, 2014 | 176 | 2014 |
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate PT Newton, L Li, B Zhou, C Schweingruber, M Hovorakova, M Xie, X Sun, ... Nature 567 (7747), 234-238, 2019 | 174 | 2019 |
Minor intron splicing is regulated by FUS and affected by ALS‐associated FUS mutants S Reber, J Stettler, G Filosa, M Colombo, D Jutzi, SC Lenzken, ... The EMBO journal 35 (14), 1504-1521, 2016 | 128 | 2016 |
Interactions of CstF-64, CstF-77, and symplekin: implications on localisation and function MD Ruepp, C Schweingruber, N Kleinschmidt, D Schümperli Molecular biology of the cell 22 (1), 91-104, 2011 | 58 | 2011 |
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis D Jutzi, S Campagne, R Schmidt, S Reber, J Mechtersheimer, F Gypas, ... Nature Communications 11 (1), 6341, 2020 | 55 | 2020 |
Identification of interactions in the NMD complex using proximity-dependent biotinylation (BioID) C Schweingruber, P Soffientini, MD Ruepp, A Bachi, O Mühlemann PLoS One 11 (3), e0150239, 2016 | 45 | 2016 |
Modeling motor neuron resilience in ALS using stem cells I Allodi, J Nijssen, JA Benitez, C Schweingruber, A Fuchs, G Bonvicini, ... Stem cell reports 12 (6), 1329-1341, 2019 | 32 | 2019 |
Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity JC Correia, Y Kelahmetoglu, PR Jannig, C Schweingruber, ... Cell Metabolism 33 (11), 2215-2230. e8, 2021 | 30 | 2021 |
LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy S Nichterwitz, J Nijssen, H Storvall, C Schweingruber, LH Comley, I Allodi, ... Genome Research 30 (8), 1083-1096, 2020 | 30 | 2020 |
The cell autonomous and non-cell autonomous aspects of neuronal vulnerability and resilience in amyotrophic lateral sclerosis C Schweingruber, E Hedlund Biology 11 (8), 1191, 2022 | 12 | 2022 |
Human motor neurons are rare and can be transcriptomically divided into known subtypes O Gautier, JA Blum, J Maksymetz, D Chen, C Schweingruber, I Mei, ... BioRxiv, 2023.04. 05.535689, 2023 | 4 | 2023 |
Single-Cell mRNA-Seq of In Vitro-Derived Human Neurons Using Smart-Seq2 C Schweingruber, J Nijssen, JA Benitez, E Hedlund Transcription Factor Regulatory Networks, 143-164, 2022 | 3 | 2022 |
Challenges of profiling motor neuron transcriptomes from human spinal cord O Gautier, JA Blum, J Maksymetz, D Chen, C Schweingruber, I Mei, ... Neuron 111 (23), 3739-3741, 2023 | 2 | 2023 |
Single cell RNA sequencing in isogenic FUS and TARDBP mutant ALS lines reveals early mitochondrial dysfunction as a common pathway in motor neurons C Schweingruber, J Nijssen, J Mechtersheimer, S Reber, M Keuper, I Mei, ... bioRxiv, 2023.03. 16.531876, 2023 | 2 | 2023 |
LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy S Nichterwitz, H Storvall, J Nijssen, LH Comley, I Allodi, M van der Lee, ... bioRxiv, 356113, 2018 | 1 | 2018 |
FUS regulates splicing of minor introns: Implications for ALS S Reber, J Stettler, G Filosa, M Colombo, D Jutzi, SC Lenzken, ... EMBO J 35 (14), 1504-1521, 2016 | 1 | 2016 |
Single cell RNA sequencing in isogenicFUSandTARDBPmutant ALS lines reveals early mitochondrial dysfunction as a common pathway in motor neurons C Schweingruber, J Nijssen, J Mechtersheimer, S Reber, M Keuper, I Mei, ... Cold Spring Harbor Laboratory, 2023 | | 2023 |
Identification of NMD-associated Proteins by Proximity-dependent Biotinylation (BioID) CK Schweingruber Medizinische Fakultät der Universität Bern, 2016 | | 2016 |
Probing interactions of NMD factors in a distance-dependent manner by BioID C Schweingruber | | 2014 |