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Christoph Schweingruber
Christoph Schweingruber
Verified email at dbb.su.se
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Cited by
Year
Nonsense-mediated mRNA decay—mechanisms of substrate mRNA recognition and degradation in mammalian cells
C Schweingruber, SC Rufener, D Zünd, A Yamashita, O Mühlemann
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (6-7 …, 2013
3852013
The host nonsense-mediated mRNA decay pathway restricts mammalian RNA virus replication
G Balistreri, P Horvath, C Schweingruber, D Zünd, G McInerney, A Merits, ...
Cell host & microbe 16 (3), 403-411, 2014
1762014
A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate
PT Newton, L Li, B Zhou, C Schweingruber, M Hovorakova, M Xie, X Sun, ...
Nature 567 (7747), 234-238, 2019
1742019
Minor intron splicing is regulated by FUS and affected by ALS‐associated FUS mutants
S Reber, J Stettler, G Filosa, M Colombo, D Jutzi, SC Lenzken, ...
The EMBO journal 35 (14), 1504-1521, 2016
1282016
Interactions of CstF-64, CstF-77, and symplekin: implications on localisation and function
MD Ruepp, C Schweingruber, N Kleinschmidt, D Schümperli
Molecular biology of the cell 22 (1), 91-104, 2011
582011
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis
D Jutzi, S Campagne, R Schmidt, S Reber, J Mechtersheimer, F Gypas, ...
Nature Communications 11 (1), 6341, 2020
552020
Identification of interactions in the NMD complex using proximity-dependent biotinylation (BioID)
C Schweingruber, P Soffientini, MD Ruepp, A Bachi, O Mühlemann
PLoS One 11 (3), e0150239, 2016
452016
Modeling motor neuron resilience in ALS using stem cells
I Allodi, J Nijssen, JA Benitez, C Schweingruber, A Fuchs, G Bonvicini, ...
Stem cell reports 12 (6), 1329-1341, 2019
322019
Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity
JC Correia, Y Kelahmetoglu, PR Jannig, C Schweingruber, ...
Cell Metabolism 33 (11), 2215-2230. e8, 2021
302021
LCM-seq reveals unique transcriptional adaptation mechanisms of resistant neurons and identifies protective pathways in spinal muscular atrophy
S Nichterwitz, J Nijssen, H Storvall, C Schweingruber, LH Comley, I Allodi, ...
Genome Research 30 (8), 1083-1096, 2020
302020
The cell autonomous and non-cell autonomous aspects of neuronal vulnerability and resilience in amyotrophic lateral sclerosis
C Schweingruber, E Hedlund
Biology 11 (8), 1191, 2022
122022
Human motor neurons are rare and can be transcriptomically divided into known subtypes
O Gautier, JA Blum, J Maksymetz, D Chen, C Schweingruber, I Mei, ...
BioRxiv, 2023.04. 05.535689, 2023
42023
Single-Cell mRNA-Seq of In Vitro-Derived Human Neurons Using Smart-Seq2
C Schweingruber, J Nijssen, JA Benitez, E Hedlund
Transcription Factor Regulatory Networks, 143-164, 2022
32022
Challenges of profiling motor neuron transcriptomes from human spinal cord
O Gautier, JA Blum, J Maksymetz, D Chen, C Schweingruber, I Mei, ...
Neuron 111 (23), 3739-3741, 2023
22023
Single cell RNA sequencing in isogenic FUS and TARDBP mutant ALS lines reveals early mitochondrial dysfunction as a common pathway in motor neurons
C Schweingruber, J Nijssen, J Mechtersheimer, S Reber, M Keuper, I Mei, ...
bioRxiv, 2023.03. 16.531876, 2023
22023
LCM-seq reveals unique transcriptional adaption mechanisms of resistant neurons in spinal muscular atrophy
S Nichterwitz, H Storvall, J Nijssen, LH Comley, I Allodi, M van der Lee, ...
bioRxiv, 356113, 2018
12018
FUS regulates splicing of minor introns: Implications for ALS
S Reber, J Stettler, G Filosa, M Colombo, D Jutzi, SC Lenzken, ...
EMBO J 35 (14), 1504-1521, 2016
12016
Single cell RNA sequencing in isogenicFUSandTARDBPmutant ALS lines reveals early mitochondrial dysfunction as a common pathway in motor neurons
C Schweingruber, J Nijssen, J Mechtersheimer, S Reber, M Keuper, I Mei, ...
Cold Spring Harbor Laboratory, 2023
2023
Identification of NMD-associated Proteins by Proximity-dependent Biotinylation (BioID)
CK Schweingruber
Medizinische Fakultät der Universität Bern, 2016
2016
Probing interactions of NMD factors in a distance-dependent manner by BioID
C Schweingruber
2014
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