| β-Arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3 PH McDonald, CW Chow, WE Miller, SA Laporte, ME Field, FT Lin, ... Science 290 (5496), 1574-1577, 2000 | 1069 | 2000 |
| Regulation of receptor fate by ubiquitination of activated β2-adrenergic receptor and β-arrestin SK Shenoy, PH McDonald, TA Kohout, RJ Lefkowitz Science 294 (5545), 1307-1313, 2001 | 1031 | 2001 |
| Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary β2-adrenergic receptor gene delivery JP Maurice, JA Hata, AS Shah, DC White, PH McDonald, PC Dolber, ... The Journal of clinical investigation 104 (1), 21-29, 1999 | 268 | 1999 |
| Restoration of β-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer SA Akhter, CA Skaer, AP Kypson, PH McDonald, KC Peppel, DD Glower, ... Proceedings of the National Academy of Sciences 94 (22), 12100-12105, 1997 | 257 | 1997 |
| Structural mechanism of ligand activation in human calcium-sensing receptor Y Geng, L Mosyak, I Kurinov, H Zuo, E Sturchler, TC Cheng, ... Elife 5, e13662, 2016 | 252 | 2016 |
| G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization K Peppel, I Boekhoff, P McDonald, H Breer, MG Caron, RJ Lefkowitz Journal of Biological Chemistry 272 (41), 25425-25428, 1997 | 219 | 1997 |
| GPCRs: Emerging anti-cancer drug targets AN Gutierrez, PH McDonald Cellular signalling 41, 65-74, 2018 | 197 | 2018 |
| Identification of NSF as a β-arrestin1-binding protein: implications for β2-adrenergic receptor regulation PH McDonald, NL Cote, FT Lin, RT Premont, JA Pitcher, RJ Lefkowitz Journal of Biological Chemistry 274 (16), 10677-10680, 1999 | 192 | 1999 |
| Identification of a motif in the carboxyl terminus of β-arrestin2 responsible for activation of JNK3 WE Miller, PH McDonald, SF Cai, ME Field, RJ Davis, RJ Lefkowitz Journal of Biological Chemistry 276 (30), 27770-27777, 2001 | 178 | 2001 |
| βArrestins: new roles in regulating heptahelical receptors' functions PH McDonald, RJ Lefkowitz Cellular signalling 13 (10), 683-689, 2001 | 175 | 2001 |
| Heme-oxygenase-1-induced protection against hypoxia/reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway AS Pachori, A Smith, P McDonald, L Zhang, VJ Dzau, LG Melo Journal of molecular and cellular cardiology 43 (5), 580-592, 2007 | 139 | 2007 |
| Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects H Zhang, E Sturchler, J Zhu, A Nieto, PA Cistrone, J Xie, LL He, K Yea, ... Nature Communications 6 (1), 8918, 2015 | 127 | 2015 |
| Augmentation of Cardiac Contractility Mediated by the Human β3-Adrenergic Receptor Overexpressed in the Hearts of Transgenic Mice TA Kohout, H Takaoka, PH McDonald, SJ Perry, L Mao, RJ Lefkowitz, ... Circulation 104 (20), 2485-2491, 2001 | 124 | 2001 |
| The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced β-arrestin 2 interaction MM Berglund, DA Schober, MA Statnick, PH McDonald, DR Gehlert Journal of Pharmacology and Experimental Therapeutics 306 (1), 147-156, 2003 | 90 | 2003 |
| Adenovirus-mediated gene transfer of the β2-adrenergic receptor to donor hearts enhances cardiac function AP Kypson, SC Hendrickson, SA Akhter, K Wilson, PH McDonald, RE Lilly, ... Gene Therapy 6 (7), 1298-1304, 1999 | 81 | 1999 |
| Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening SP Brothers, SA Saldanha, TP Spicer, M Cameron, BA Mercer, P Chase, ... Molecular pharmacology 77 (1), 46-57, 2010 | 77 | 2010 |
| Melanocortin‐3 receptors are involved in adaptation to restricted feeding K Begriche, OJ Marston, J Rossi, LK Burke, P McDonald, LK Heisler, ... Genes, Brain and Behavior 11 (3), 291-302, 2012 | 62 | 2012 |
| Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison S Dabul, A Bathgate-Siryk, TR Valero, M Jafferjee, E Sturchler, ... Scientific reports 5 (1), 8116, 2015 | 47 | 2015 |
| Melanocortin-3 receptors and metabolic homeostasis K Begriche, C Girardet, P McDonald, AA Butler Progress in molecular biology and translational science 114, 109-146, 2013 | 46 | 2013 |
| Structural basis for auxiliary subunit KCTD16 regulation of the GABAB receptor H Zuo, I Glaaser, Y Zhao, I Kurinov, L Mosyak, H Wang, J Liu, J Park, ... Proceedings of the National Academy of Sciences 116 (17), 8370-8379, 2019 | 43 | 2019 |
