Jeffrey Klomp
Jeffrey Klomp
Assistant Professor, University of North Carolina
Verified email at
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Birt-Hogg-Dube renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression
JA Klomp, D Petillo, NM Niemi, KJ Dykema, J Chen, XJ Yang, A Sääf, ...
BMC medical genomics 3, 1-12, 2010
N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability
K Kruse, QS Lee, Y Sun, J Klomp, X Yang, F Huang, MY Sun, S Zhao, ...
Journal of Cell Biology 218 (1), 299-316, 2019
Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis
MS Nahorski, L Seabra, A Straatman-Iwanowska, A Wingenfeld, ...
Human molecular genetics 21 (24), 5268-5279, 2012
MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis
NM Niemi, NJ Lanning, JA Klomp, SW Tait, Y Xu, KJ Dykema, LO Murphy, ...
Molecular and cellular biology 31 (7), 1357-1368, 2011
Deregulation of E2-EPF ubiquitin carrier protein in papillary renal cell carcinoma
FC Roos, AJ Evans, W Brenner, B Wondergem, J Klomp, P Heir, O Roche, ...
The American journal of pathology 178 (2), 853-860, 2011
A cysteine-clamp gene drives embryo polarity in the midge Chironomus
J Klomp, D Athy, CW Kwan, NI Bloch, T Sandmann, S Lemke, ...
Science 348 (6238), 1040-1042, 2015
Molecular mechanisms underlying the exceptional adaptations of batoid fins
T Nakamura, J Klomp, J Pieretti, I Schneider, AR Gehrke, NH Shubin
Proceedings of the National Academy of Sciences 112 (52), 15940-15945, 2015
An omics perspective on cancer research
Springer, 2010
The ERK mitogen-activated protein kinase signaling network: the final frontier in RAS signal transduction
JE Klomp, JA Klomp, CJ Der
Biochemical Society Transactions 49 (1), 253-267, 2021
Embryo polarity in moth flies and mosquitoes relies on distinct old genes with localized transcript isoforms
Y Yoon, J Klomp, I Martin-Martin, F Criscione, E Calvo, J Ribeiro, ...
Elife 8, e46711, 2019
Method for dual viral vector mediated CRISPR-Cas9 gene disruption in primary human endothelial cells
H Gong, M Liu, J Klomp, BJ Merrill, J Rehman, AB Malik
Scientific Reports 7 (1), 42127, 2017
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
JE Klomp, YS Lee, CM Goodwin, B Papke, JA Klomp, AM Waters, ...
Cell reports 37 (9), 2021
Collaborative study from the Bladder Cancer Advocacy Network for the genomic analysis of metastatic urothelial cancer
JS Damrauer, W Beckabir, J Klomp, M Zhou, ER Plimack, MD Galsky, ...
Nature communications 13 (1), 6658, 2022
Comprehensive transcriptomic profiling reveals SOX7 as an early regulator of angiogenesis in hypoxic human endothelial cells
J Klomp, J Hyun, JE Klomp, K Pajcini, J Rehman, AB Malik
Journal of Biological Chemistry 295 (15), 4796-4808, 2020
Renal Cancer
JA Libertino, JR Gee
Springer International Publishing, 2020
Genome-wide matching of genes to cellular roles using guilt-by-association models derived from single sample analysis
JA Klomp, KA Furge
BMC research notes 5, 1-15, 2012
How the devil ray got its horns: the evolution and development of cephalic lobes in myliobatid stingrays (Batoidea: Myliobatidae)
JD Swenson, J Klomp, RA Fisher, KD Crow
Frontiers in Ecology and Evolution 6, 181, 2018
Analysis of biological networks in the endothelium with biomimetic microsystem platform
K Kruse, J Klomp, M Sun, Z Chen, D Santana, F Huang, P Kanabar, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 317 (3 …, 2019
Abstract B034: Determination of KRAS-and ERK-regulated phosphoproteomes in KRAS-mutant cancers
JE Klomp, JA Klomp, NJ Diehl, CA Edwards, K Drizyte-Miller, ...
Molecular Cancer Research 21 (5_Supplement), B034-B034, 2023
Urothelial cancer-GENOmic analysis to improve patient outcomes and research (UC-GENOME): a bladder cancer advocacy network (BCAN) led collaborative research study
JS Damrauer, J Klomp, W Beck, M Zhou, E Plimack, M Galsky, P Grivas, ...
Cancer Research 81 (13_Supplement), 2188-2188, 2021
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