| SARS-CoV-2 disrupts splicing, translation, and protein trafficking to suppress host defenses AK Banerjee, MR Blanco, EA Bruce, DD Honson, LM Chen, A Chow, ... Cell 183 (5), 1325-1339. e21, 2020 | 405 | 2020 |
| A Rab11-and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA MJ Amorim, EA Bruce, EKC Read, Á Foeglein, R Mahen, AD Stuart, ... Journal of virology 85 (9), 4143-4156, 2011 | 275 | 2011 |
| The Rab11 pathway is required for influenza A virus budding and filament formation EA Bruce, P Digard, AD Stuart Journal of virology 84 (12), 5848-5859, 2010 | 236 | 2010 |
| Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step EA Bruce, ML Huang, GA Perchetti, S Tighe, P Laaguiby, JJ Hoffman, ... PLoS biology 18 (10), e3000896, 2020 | 158 | 2020 |
| Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ... Science 373 (6557), 931-936, 2021 | 138 | 2021 |
| Live imaging of SARS-CoV-2 infection in mice reveals neutralizing antibodies require Fc function for optimal efficacy I Ullah, J Prévost, M Ladinsky, H Stone, M Lu, SP Anand, ... | 116 | 2021 |
| Intestinal host response to SARS-CoV-2 infection and COVID-19 outcomes in patients with gastrointestinal symptoms AE Livanos, D Jha, F Cossarini, AS Gonzalez-Reiche, M Tokuyama, ... Gastroenterology, 2021 | 114 | 2021 |
| The major cellular sterol regulatory pathway is required for Andes virus infection J Petersen, MJ Drake, EA Bruce, AM Riblett, CA Didigu, CB Wilen, ... PLoS Pathog 10 (2), e1003911, 2014 | 91 | 2014 |
| Budding of filamentous and non-filamentous influenza A virus occurs via a VPS4 and VPS28-independent pathway EA Bruce, L Medcalf, CM Crump, SL Noton, AD Stuart, HM Wise, D Elton, ... Virology 390 (2), 268-278, 2009 | 72 | 2009 |
| Role of the Rab11 pathway in negative-strand virus assembly. EA Bruce, A Stuart, MW McCaffrey, P Digard Biochemical Society Transactions 40 (6), 2012 | 50 | 2012 |
| Copine A is required for cytokinesis, contractile vacuole function, and development in Dictyostelium CK Damer, M Bayeva, PS Kim, LK Ho, ES Eberhardt, CI Socec, JS Lee, ... Eukaryotic cell 6 (3), 430-442, 2007 | 43 | 2007 |
| Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro N Drayman, KA Jones, SA Azizi, HM Froggatt, K Tan, NI Maltseva, S Chen, ... bioRxiv, 2020 | 40 | 2020 |
| A map of the arenavirus nucleoprotein-host protein interactome reveals that Junín virus selectively impairs the antiviral activity of double-stranded RNA-activated protein … BR King, D Hershkowitz, PL Eisenhauer, ME Weir, CM Ziegler, J Russo, ... Journal of virology 91 (15), e00763-17, 2017 | 40 | 2017 |
| The lymphocytic choriomeningitis virus matrix protein PPXY late domain drives the production of defective interfering particles CM Ziegler, P Eisenhauer, EA Bruce, ME Weir, BR King, JP Klaus, ... PLoS pathogens 12 (3), e1005501, 2016 | 40 | 2016 |
| ‘All In’: a pragmatic framework for COVID‐19 testing and action on a global scale SD Pettit, KR Jerome, D Rouquié, B Mari, P Barbry, Y Kanda, ... EMBO Molecular Medicine 12 (6), e12634, 2020 | 39 | 2020 |
| Release of filamentous and spherical influenza A virus is not restricted by tetherin EA Bruce, TE Abbink, HM Wise, R Rollason, RP Galao, G Banting, SJ Neil, ... Journal of general virology 93 (5), 963-969, 2012 | 35 | 2012 |
| Kinetics and isotype assessment of antibodies targeting the spike protein receptor‐binding domain of severe acute respiratory syndrome‐coronavirus‐2 in COVID‐19 patients as a … NR Graham, AN Whitaker, CA Strother, AK Miles, D Grier, BD McElvany, ... Clinical & translational immunology 9 (10), e1189, 2020 | 34 | 2020 |
| Quantitative measurement of infectious virus in SARS-CoV-2 Alpha, Delta and Epsilon variants reveals higher infectivity (viral titer: RNA ratio) in clinical samples containing … HW Despres, MG Mills, DJ Shirley, MM Schmidt, ML Huang, KR Jerome, ... medRxiv, 2021 | 31 | 2021 |
| RT-qPCR Detection of SARS-CoV-2 RNA from Patient Nasopharyngeal Swab Using Qiagen RNEasy Kits or Directly via Omission of an RNA Extraction Step EA Bruce, S Tighe, JJ Hoffman, P Laaguiby, DL Gerrard, SA Diehl, ... bioRxiv, 2020 | 28 | 2020 |
| Predicting infectivity: comparing four PCR‐based assays to detect culturable SARS‐CoV‐2 in clinical samples EA Bruce, MG Mills, R Sampoleo, GA Perchetti, ML Huang, HW Despres, ... EMBO molecular medicine 14 (2), e15290, 2022 | 27 | 2022 |
Paul DigardProfessor of Virology, the Roslin InstituteVerified email at roslin.ed.ac.uk
