| Protein arginine-methyltransferase-dependent oncogenesis N Cheung, LC Chan, A Thompson, ML Cleary, CWE So Nature cell biology 9 (10), 1208-1215, 2007 | 356 | 2007 |
| β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cells J Yeung, MT Esposito, A Gandillet, BB Zeisig, E Griessinger, D Bonnet, ... Cancer cell 18 (6), 606-618, 2010 | 329 | 2010 |
| MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice CW So, H Karsunky, E Passegué, A Cozzio, IL Weissman, ML Cleary Cancer cell 3 (2), 161-171, 2003 | 266 | 2003 |
| Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias CW So, M Lin, PM Ayton, EH Chen, ML Cleary Cancer cell 4 (2), 99-110, 2003 | 253 | 2003 |
| Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9 CW So, H Karsunky, P Wong, IL Weissman, ML Cleary Blood 103 (8), 3192-3199, 2004 | 211 | 2004 |
| Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia L Kearney, D Gonzalez De Castro, J Yeung, J Procter, SW Horsley, ... Blood, The Journal of the American Society of Hematology 113 (3), 646-648, 2009 | 207 | 2009 |
| Targeting aberrant epigenetic networks mediated by PRMT1 and KDM4C in acute myeloid leukemia N Cheung, TK Fung, BB Zeisig, K Holmes, JK Rane, KA Mowen, MG Finn, ... Cancer cell 29 (1), 32-48, 2016 | 175 | 2016 |
| Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors MT Esposito, L Zhao, TK Fung, JK Rane, A Wilson, N Martin, J Gil, ... Nature medicine 21 (12), 1481-1490, 2015 | 172 | 2015 |
| HOTTIP lncRNA promotes hematopoietic stem cell self-renewal leading to AML-like disease in mice H Luo, G Zhu, J Xu, Q Lai, B Yan, Y Guo, TK Fung, BB Zeisig, Y Cui, J Zha, ... Cancer cell 36 (6), 645-659. e8, 2019 | 147 | 2019 |
| Functional crosstalk between Bmi1 and MLL/Hoxa9 axis in establishment of normal hematopoietic and leukemic stem cells LL Smith, J Yeung, BB Zeisig, N Popov, I Huijbers, J Barnes, AJ Wilson, ... Cell stem cell 8 (6), 649-662, 2011 | 146 | 2011 |
| EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia CW So, C Caldas, MM Liu, SJ Chen, QH Huang, LJ Gu, MH Sham, ... Proceedings of the National Academy of Sciences 94 (6), 2563-2568, 1997 | 142 | 1997 |
| Common mechanism for oncogenic activation of MLL by forkhead family proteins CW So, ML Cleary Blood, The Journal of the American Society of Hematology 101 (2), 633-639, 2003 | 134 | 2003 |
| MLL-AFX requires the transcriptional effector domains of AFX to transform myeloid progenitors and transdominantly interfere with forkhead protein function CW So, ML Cleary Molecular and cellular biology, 2002 | 124 | 2002 |
| SnapShot: acute myeloid leukemia BB Zeisig, AG Kulasekararaj, GJ Mufti, CWE So Cancer cell 22 (5), 698-698. e1, 2012 | 111 | 2012 |
| Recruitment of RXR by homotetrameric RARα fusion proteins is essential for transformation BB Zeisig, C Kwok, A Zelent, P Shankaranarayanan, H Gronemeyer, ... Cancer cell 12 (1), 36-51, 2007 | 111 | 2007 |
| Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance M Vukovic, AV Guitart, C Sepulveda, A Villacreces, E O'Duibhir, ... Journal of Experimental Medicine 212 (13), 2223-2234, 2015 | 106 | 2015 |
| The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia MF Arteaga, JH Mikesch, J Qiu, J Christensen, K Helin, SC Kogan, ... Cancer cell 23 (3), 376-389, 2013 | 100 | 2013 |
| DNA damage accumulation and repair defects in acute myeloid leukemia: implications for pathogenesis, disease progression, and chemotherapy resistance MT Esposito, CWE So Chromosoma 123, 545-561, 2014 | 94 | 2014 |
| Dimerization: a versatile switch for oncogenesis CW So, ML Cleary Blood 104 (4), 919-922, 2004 | 93 | 2004 |
| Exon scrambling of MLL transcripts occur commonly and mimic partial genomic duplication of the gene C Caldas, CW So, A MacGregor, AM Ford, B McDonald, LC Chan, ... Gene 208 (2), 167-176, 1998 | 86 | 1998 |
