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James Hockley
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Single-cell RNAseq reveals seven classes of colonic sensory neuron
JRF Hockley, TS Taylor, G Callejo, AL Wilbrey, A Gutteridge, K Bach, ...
Gut 68 (4), 633-644, 2019
2142019
Functional and molecular characterization of mechanoinsensitive “silent” nociceptors
V Prato, FJ Taberner, JRF Hockley, G Callejo, A Arcourt, B Tazir, ...
Cell reports 21 (11), 3102-3115, 2017
1622017
Multiple roles for NaV1. 9 in the activation of visceral afferents by noxious inflammatory, mechanical, and human disease–derived stimuli
JRF Hockley, G Boundouki, V Cibert-Goton, C McGuire, PK Yip, C Chan, ...
PAIN® 155 (10), 1962-1975, 2014
842014
Visceral and somatic pain modalities reveal NaV1.7‐independent visceral nociceptive pathways
JRF Hockley, R González‐Cano, S McMurray, MA Tejada‐Giraldez, ...
The Journal of physiology 595 (8), 2661-2679, 2017
792017
P2Y receptors sensitize mouse and human colonic nociceptors
JRF Hockley, MM Tranter, C McGuire, G Boundouki, V Cibert-Goton, ...
Journal of Neuroscience 36 (8), 2364-2376, 2016
692016
Genome-wide association analysis of pain severity in dysmenorrhea identifies association at chromosome 1p13. 2, near the nerve growth factor locus
AV Jones, JRF Hockley, C Hyde, D Gorman, A Sredic-Rhodes, J Bilsland, ...
Pain 157 (11), 2571-2581, 2016
552016
Acute inflammation sensitizes knee-innervating sensory neurons and decreases mouse digging behavior in a TRPV1-dependent manner
S Chakrabarti, LA Pattison, K Singhal, JRF Hockley, G Callejo, ESJ Smith
Neuropharmacology 143, 49-62, 2018
492018
5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein–coupled receptor D
T Bautzova, JRF Hockley, T Perez-Berezo, J Pujo, MM Tranter, ...
Science signaling 11 (561), eaal2171, 2018
482018
Ex vivo study of human visceral nociceptors
C McGuire, G Boundouki, JRF Hockley, D Reed, V Cibert-Goton, M Peiris, ...
Gut 67 (1), 86-96, 2018
472018
Peripheral KV7 channels regulate visceral sensory function in mouse and human colon
M Peiris, JRF Hockley, DE Reed, ESJ Smith, DC Bulmer, LA Blackshaw
Molecular pain 13, 1744806917709371, 2017
452017
Using transfer learning from prior reference knowledge to improve the clustering of single-cell RNA-Seq data
B Mieth, JRF Hockley, N Görnitz, MMC Vidovic, KR Müller, A Gutteridge, ...
Scientific reports 9 (1), 20353, 2019
322019
The voltage‐gated sodium channel NaV1.9 in visceral pain
JRF Hockley, WJ Winchester, DC Bulmer
Neurogastroenterology & Motility 28 (3), 316-326, 2016
322016
Human visceral nociception: findings from translational studies in human tissue
JRF Hockley, ESJ Smith, DC Bulmer
American Journal of Physiology-Gastrointestinal and Liver Physiology 315 (4 …, 2018
222018
Human labor pain is influenced by the voltage-gated potassium channel KV6. 4 subunit
MC Lee, MS Nahorski, JRF Hockley, VB Lu, G Ison, LA Pattison, G Callejo, ...
Cell reports 32 (3), 2020
202020
In silico screening of GMQ-like compounds reveals guanabenz and sephin1 as new allosteric modulators of acid-sensing ion channel 3
G Callejo, LA Pattison, JC Greenhalgh, S Chakrabarti, E Andreopoulou, ...
Biochemical Pharmacology 174, 113834, 2020
142020
Functional and anatomical deficits in visceral nociception with age: a mechanism of silent appendicitis in the elderly?
V Cibert-Goton, VWS Kung, C McGuire, JRF Hockley, MM Tranter, ...
Pain 161 (4), 773-786, 2020
112020
Acid and inflammatory sensitisation of naked mole-rat colonic afferent nerves
JRF Hockley, KH Barker, TS Taylor, G Callejo, ZM Husson, DC Bulmer, ...
Molecular Pain 16, 1744806920903150, 2020
102020
Galanin suppresses visceral afferent responses to noxious mechanical and inflammatory stimuli
TS Taylor, P Konda, SS John, DC Bulmer, JRF Hockley, ESJ Smith
Physiological reports 8 (2), e14326, 2020
72020
The role of Nav1. 9 in the activation of visceral afferent fibres by human inflammatory supernatants
G Boundouki, J Hockley, C McGuire, C Knowles, Q Aziz, M Baker, ...
NEUROGASTROENTEROLOGY AND MOTILITY 24, 41-41, 2012
12012
GPR35 inhibits TRPA1-mediated colonic afferent hypersensitivity through suppression of Substance P release
RA Gupta, JP Higham, P Urriola-Munoz, KH Barker, LW Paine, ...
bioRxiv, 2023.09. 12.557415, 2023
2023
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