| Integrative analysis of 111 reference human epigenomes A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ... Nature 518 (7539), 317-330, 2015 | 5966 | 2015 |
| Mutational heterogeneity in cancer and the search for new cancer-associated genes MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ... Nature 499 (7457), 214-218, 2013 | 5765 | 2013 |
| The repertoire of mutational signatures in human cancer LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ... Nature 578 (7793), 94-101, 2020 | 2405 | 2020 |
| Patterns and rates of exonic de novo mutations in autism spectrum disorders BM Neale, Y Kou, L Liu, A Ma’Ayan, KE Samocha, A Sabo, CF Lin, ... Nature 485 (7397), 242-245, 2012 | 2008 | 2012 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1680* | 2020 |
| Oscillations and variability in the p53 system N Geva‐Zatorsky, N Rosenfeld, S Itzkovitz, R Milo, A Sigal, E Dekel, ... Molecular systems biology 2 (1), 2006.0033, 2006 | 795 | 2006 |
| Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors VA Adalsteinsson, G Ha, SS Freeman, AD Choudhury, DG Stover, ... Nature communications 8 (1), 1324, 2017 | 745 | 2017 |
| Whole-genome sequence variation, population structure and demographic history of the Dutch population Nature genetics 46 (8), 818-825, 2014 | 708 | 2014 |
| Genome sequencing reveals insights into physiology and longevity of the naked mole rat EB Kim, X Fang, AA Fushan, Z Huang, AV Lobanov, L Han, SM Marino, ... Nature 479 (7372), 223-227, 2011 | 674 | 2011 |
| Cell-of-origin chromatin organization shapes the mutational landscape of cancer P Polak, R Karlić, A Koren, R Thurman, R Sandstrom, MS Lawrence, ... Nature 518 (7539), 360-364, 2015 | 577 | 2015 |
| Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors D Miao, CA Margolis, NI Vokes, D Liu, A Taylor-Weiner, SM Wankowicz, ... Nature genetics 50 (9), 1271-1281, 2018 | 496 | 2018 |
| A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer P Polak, J Kim, LZ Braunstein, R Karlic, NJ Haradhavala, G Tiao, ... Nature genetics 49 (10), 1476-1486, 2017 | 488 | 2017 |
| RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues K Yizhak, F Aguet, J Kim, JM Hess, K Kübler, J Grimsby, R Frazer, ... Science 364 (6444), eaaw0726, 2019 | 436 | 2019 |
| Mutational strand asymmetries in cancer genomes reveal mechanisms of DNA damage and repair NJ Haradhvala, P Polak, P Stojanov, KR Covington, E Shinbrot, JM Hess, ... Cell 164 (3), 538-549, 2016 | 415 | 2016 |
| Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors J Kim, KW Mouw, P Polak, LZ Braunstein, A Kamburov, G Tiao, ... Nature genetics 48 (6), 600-606, 2016 | 407 | 2016 |
| Genome-wide patterns and properties of de novo mutations in humans LC Francioli, PP Polak, A Koren, A Menelaou, S Chun, I Renkens, ... Nature genetics 47 (7), 822-826, 2015 | 405 | 2015 |
| Structural alterations driving castration-resistant prostate cancer revealed by linked-read genome sequencing SR Viswanathan, G Ha, AM Hoff, JA Wala, J Carrot-Zhang, CW Whelan, ... Cell 174 (2), 433-447. e19, 2018 | 320 | 2018 |
| Genomic characterization of biliary tract cancers identifies driver genes and predisposing mutations CP Wardell, M Fujita, T Yamada, M Simbolo, M Fassan, R Karlic, P Polak, ... Journal of hepatology 68 (5), 959-969, 2018 | 310 | 2018 |
| Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution S Kasar, J Kim, R Improgo, G Tiao, P Polak, N Haradhvala, MS Lawrence, ... Nature communications 6 (1), 8866, 2015 | 271 | 2015 |
| Differential relationship of DNA replication timing to different forms of human mutation and variation A Koren, P Polak, J Nemesh, JJ Michaelson, J Sebat, SR Sunyaev, ... The American Journal of Human Genetics 91 (6), 1033-1040, 2012 | 270 | 2012 |
