Mihaly Hajos
Mihaly Hajos
Professor Adjunct, Yale University School of Medicine
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A novel positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization
RS Hurst, M Hajós, M Raggenbass, TM Wall, NR Higdon, JA Lawson, ...
Journal of Neuroscience 25 (17), 4396-4405, 2005
Neurophysiological biomarkers for drug development in schizophrenia
DC Javitt, KM Spencer, GK Thaker, G Winterer, M Hajós
Nature Reviews Drug Discovery 7 (1), 68-83, 2008
Interaction between a selective 5‐HT1A receptor antagonist and an SSRI in vivo: effects on 5‐HT cell firing and extracellular 5‐HT
SE Gartside, V Umbers, M Hajos, T Sharp
British journal of pharmacology 115 (6), 1064-1070, 1995
An electrophysiological and neuroanatomical study of the medial prefrontal cortical projection to the midbrain raphe nuclei in the rat
M Hajós, CD Richards, AD Székely, T Sharp
Neuroscience 87 (1), 95-108, 1998
Preclinical characterization of selective phosphodiesterase 10A inhibitors: a new therapeutic approach to the treatment of schizophrenia
CJ Schmidt, DS Chapin, J Cianfrogna, ML Corman, M Hajos, JF Harms, ...
Journal of Pharmacology and Experimental Therapeutics 325 (2), 681-690, 2008
The selective α7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-azabicyclo [2.2. 2] oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic …
M Hajos, RS Hurst, WE Hoffmann, M Krause, TM Wall, NR Higdon, ...
Journal of Pharmacology and Experimental Therapeutics 312 (3), 1213-1222, 2005
The selective norepinephrine reuptake inhibitor antidepressant reboxetine: pharmacological and clinical profile
M Hajós, JC Fleishaker, JK Filipiak‐Reisner, MT Brown, EHF Wong
CNS drug reviews 10 (1), 23-44, 2004
Discovery and structure− activity relationship of quinuclidine benzamides as agonists of α7 nicotinic acetylcholine receptors
AL Bodnar, LA Cortes-Burgos, KK Cook, DM Dinh, VE Groppi, M Hajos, ...
Journal of medicinal chemistry 48 (4), 905-908, 2005
Role of the medial prefrontal cortex in 5‐HT1A receptor‐induced inhibition of 5‐HT neuronal activity in the rat
M Hajós, É Hajós‐Korcsok, T Sharp
British journal of pharmacology 126 (8), 1741-1750, 1999
Discovery of N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide, an Agonist of the α7 Nicotinic Acetylcholine Receptor, for the Potential …
DG Wishka, DP Walker, KM Yates, SC Reitz, S Jia, JK Myers, KL Olson, ...
Journal of medicinal chemistry 49 (14), 4425-4436, 2006
Brain uncoupling protein 2: uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers
TL Horvath, CH Warden, M Hajos, A Lombardi, F Goglia, S Diano
Journal of Neuroscience 19 (23), 10417-10427, 1999
Nicotine decreases DNA methyltransferase 1 expression and glutamic acid decarboxylase 67 promoter methylation in GABAergic interneurons
R Satta, E Maloku, A Zhubi, F Pibiri, M Hajos, E Costa, A Guidotti
Proceedings of the National Academy of Sciences 105 (42), 16356-16361, 2008
Translating glutamate: from pathophysiology to treatment
DC Javitt, D Schoepp, PW Kalivas, ND Volkow, C Zarate, K Merchant, ...
Science translational medicine 3 (102), 102mr2-102mr2, 2011
Evidence for a role of GABA interneurones in the cortical modulation of midbrain 5-hydroxytryptamine neurones
V Varga, AD Szekely, A Csillag, T Sharp, M Hajos
Neuroscience 106 (4), 783-792, 2001
Elicited hippocampal theta rhythm: a screen for anxiolytic and procognitive drugs through changes in hippocampal function?
N McNaughton, B Kocsis, M Hajos
Behavioural pharmacology 18 (5-6), 329-346, 2007
Activation of cannabinoid-1 receptors disrupts sensory gating and neuronal oscillation: relevance to schizophrenia
M Hajós, WE Hoffmann, B Kocsis
Biological psychiatry 63 (11), 1075-1083, 2008
Reduction of brain kynurenic acid improves cognitive function
R Kozak, BM Campbell, CA Strick, W Horner, WE Hoffmann, T Kiss, ...
Journal of Neuroscience 34 (32), 10592-10602, 2014
Auditory sensory gating in hippocampus and reticular thalamic neurons in anesthetized rats
M Krause, WE Hoffmann, M Hajós
Biological psychiatry 53 (3), 244-253, 2003
In vivo inhibition of neuronal activity in the rat ventromedial prefrontal cortex by midbrain-raphe nuclei: role of 5-HT1A receptors
M Hajós, SE Gartside, V Varga, T Sharp
Neuropharmacology 45 (1), 72-81, 2003
Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat
M Hajos, SE Gartside, AEP Villa, T Sharp
Neuroscience 69 (1), 189-197, 1995
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