Birgit Wilding
Birgit Wilding
Unknown affiliation
Verified email at tugraz.at
Title
Cited by
Cited by
Year
Demonstrating in-cell target engagement using a pirin protein degradation probe (CCT367766)
NEA Chessum, SY Sharp, JJ Caldwell, AE Pasqua, B Wilding, ...
Journal of medicinal chemistry 61 (3), 918-933, 2018
452018
Nitrile reductase from Geobacillus kaustophilus: a potential catalyst for a new nitrile biotransformation reaction
B Wilding, M Winkler, B Petschacher, R Kratzer, A Glieder, N Klempier
Advanced Synthesis & Catalysis 354 (11‐12), 2191-2198, 2012
312012
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen
Journal of Medicinal Chemistry 60 (1), 180-201, 2017
252017
Targeting the Substrate Binding Site of E. coli Nitrile Reductase QueF by Modeling, Substrate and Enzyme Engineering
B Wilding, M Winkler, B Petschacher, R Kratzer, S Egger, G Steinkellner, ...
Chemistry–A European Journal 19 (22), 7007-7012, 2013
232013
Newest Developments in the Preparation of Thieno[2,3-d]pyrimidines
B Wilding, N Klempier
Organic Preparations and Procedures International 49 (3), 183-215, 2017
142017
An investigation of nitrile transforming enzymes in the chemo-enzymatic synthesis of the taxol sidechain
B Wilding, AB Veselá, JJB Perry, GW Black, M Zhang, L Martínková, ...
Organic & biomolecular chemistry 13 (28), 7803-7812, 2015
142015
A practical synthesis of 5-functionalized thieno [2, 3-d] pyrimidines
B Wilding, S Faschauner, N Klempier
Tetrahedron letters 56 (30), 4486-4489, 2015
122015
A convenient synthetic route to substituted pyrrolo [2, 3-b] pyridines via a novel ethylene-bridged compound
B Wilding, C Vidovic, N Klempier
Tetrahedron letters 56 (47), 6606-6609, 2015
72015
Privileged structures and polypharmacology within and between protein families
J Meyers, NEA Chessum, S Ali, NY Mok, B Wilding, AE Pasqua, ...
ACS medicinal chemistry letters 9 (12), 1199-1204, 2018
62018
Kinetic analysis and probing with substrate analogues of the reaction pathway of the nitrile reductase QueF from Escherichia coli
J Jung, T Czabany, B Wilding, N Klempier, B Nidetzky
Journal of Biological Chemistry 291 (49), 25411-25426, 2016
52016
The Nitrile‐Forming Enzyme 7‐Cyano‐7‐Deazaguanine Synthase from Geobacillus kaustophilus: A Reverse Nitrilase?
M Winkler, K Dokulil, H Weber, T Pavkov‐Keller, B Wilding
ChemBioChem 16 (16), 2373-2378, 2015
32015
Quinoline derivatives as inhibitors of heat shock factor 1 pathway activity
K Jones, M Cheeseman, N Chessum, E Pasqua, L Evans, M Tucker, ...
US Patent 10,647,678, 2020
2020
Confirmation of in-cell target engagement using the proteolysis targeting chimeras (PROTACs) against pirin
SY Sharp, NE Chessum, JJ Caldwell, MV Powers, AE Pasqua, B Wilding, ...
Cancer Research 78 (13 Supplement), 2976-2976, 2018
2018
Discovery of CCT251236 from an HSF1 phenotypic screen: A pirin ligand with efficacy in an ovarian adenocarcinoma model
E Pasqua, M Cheeseman, N Chessum, C Rye, M Tucker, B Wilding, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Targeting Protein Synthesis, Folding, and Degradation Pathways in Cancer
AE Pasqua, B Wilding, MD Cheeseman, K Jones
Elsevier, 2017
2017
Enzymatic Reductions of unconventioal substrates: Carboxylates and Nitriles
M Winkler, K Napora-Wijata, B Wilding, N Klempier
2014
Unconventional Enzymatic Reductions: Nitriles and Carboxylates as Substrates
M Winkler, K Napora-Wijata, B Wilding, N Klempier
2014
In Vitro Reconstruction of Queuosine biosynthesis in Geobacillus kaustophilus: two step cascade from 7-carboxy-7-deazaguanin to PreQ1
K Dokulil, B Wilding, G Offenmüller, N Klempier, M Winkler
2014
Book Review: The Weirdness of Being
R Winkler
Indo-Pacific Journal of Phenomenology 14 (2), 2014
2014
Biological nitrile reduction–exploring a remarkable reaction
B Wilding, B Petschacher, M Winkler, R Kratzer, G Steinkellner, ...
15th Austrian Chemistry Days 2013, 2013
2013
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