Andrew Philip Weng
Andrew Philip Weng
Terry Fox Laboratory and Department of Pathology, British Columbia Cancer Agency
Verified email at
Cited by
Cited by
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
AP Weng, AA Ferrando, W Lee, JP Morris IV, LB Silverman, ...
Science 306 (5694), 269-271, 2004
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
MA Shipp, KN Ross, P Tamayo, AP Weng, JL Kutok, RCT Aguiar, ...
Nature medicine 8 (1), 68-74, 2002
c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
AP Weng, JM Millholland, Y Yashiro-Ohtani, ML Arcangeli, A Lau, C Wai, ...
Genes & development 20 (15), 2096-2109, 2006
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ...
Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
N Kwiatkowski, T Zhang, PB Rahl, BJ Abraham, J Reddy, SB Ficarro, ...
Nature 511 (7511), 616-620, 2014
Critical assessment of automated flow cytometry data analysis techniques
N Aghaeepour, G Finak, FlowCAP Consortium, Dream Consortium, ...
Nature methods 10 (3), 228-238, 2013
Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling
AP Weng, Y Nam, MS Wolfe, WS Pear, JD Griffin, SC Blacklow, JC Aster
Molecular and cellular biology, 2003
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ...
Cell 167 (5), 1145-1149, 2016
Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma
R Kridel, B Meissner, S Rogic, M Boyle, A Telenius, B Woolcock, ...
Blood, The Journal of the American Society of Hematology 119 (9), 1963-1971, 2012
Mastermind critically regulates Notch-mediated lymphoid cell fate decisions
I Maillard, AP Weng, AC Carpenter, CG Rodriguez, H Sai, L Xu, D Allman, ...
Blood 104 (6), 1696-1702, 2004
The public repository of xenografts enables discovery and randomized phase II-like trials in mice
EC Townsend, MA Murakami, A Christodoulou, AL Christie, J Köster, ...
Cancer cell 29 (4), 574-586, 2016
Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia
SM Chan, AP Weng, R Tibshirani, JC Aster, PJ Utz
Blood, The Journal of the American Society of Hematology 110 (1), 278-286, 2007
Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1
DJ Izon, JC Aster, Y He, A Weng, FG Karnell, V Patriub, L Xu, S Bakkour, ...
Immunity 16 (2), 231-243, 2002
Multiple niches for Notch in cancer: context is everything
AP Weng, JC Aster
Current opinion in genetics & development 14 (1), 48-54, 2004
Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats
C Sanchez-Irizarry, AC Carpenter, AP Weng, WS Pear, JC Aster, ...
Molecular and cellular biology 24 (21), 9265-9273, 2004
Structural requirements for assembly of the CSLˇ intracellular Notch1ˇ Mastermind-like 1 transcriptional activation complex
Y Nam, AP Weng, JC Aster, SC Blacklow
Journal of Biological Chemistry 278 (23), 21232-21239, 2003
Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling
AW Zhang, C O’Flanagan, EA Chavez, JLP Lim, N Ceglia, A McPherson, ...
Nature methods 16 (10), 1007-1015, 2019
Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia
A Gutierrez, L Pan, RWJ Groen, F Baleydier, A Kentsis, J Marineau, ...
The Journal of clinical investigation 124 (2), 644-655, 2014
Comprehensive microRNA expression profiling of the hematopoietic hierarchy
OI Petriv, F Kuchenbauer, AD Delaney, V Lecault, A White, D Kent, ...
Proceedings of the National Academy of Sciences 107 (35), 15443-15448, 2010
High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling
H Medyouf, S Gusscott, H Wang, JC Tseng, C Wai, O Nemirovsky, ...
Journal of Experimental Medicine 208 (9), 1809-1822, 2011
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