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Christiane A. Opitz
Christiane A. Opitz
Division Head "Metabolic Crosstalk in Cancer", German Cancer Research Center (DKFZ)
Verified email at dkfz.de - Homepage
Title
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Cited by
Year
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
CA Opitz, UM Litzenburger, F Sahm, M Ott, I Tritschler, S Trump, ...
Nature 478 (7368), 197-203, 2011
18422011
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
M Platten, EAA Nollen, UF Röhrig, F Fallarino, CA Opitz
Nature reviews Drug discovery 18 (5), 379-401, 2019
9142019
Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts
I Makarenko, CA Opitz, MC Leake, C Neagoe, M Kulke, JK Gwathmey, ...
Circulation research 95 (7), 708-716, 2004
4172004
Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2, 3-dioxygenase-1 via …
CA Opitz, UM Litzenburger, C Lutz, TV Lanz, I Tritschler, A Köppel, ...
Stem cells 27 (4), 909-919, 2009
3912009
Isoform diversity of giant proteins in relation to passive and active contractile properties of rabbit skeletal muscles
LG Prado, I Makarenko, C Andresen, M Krüger, CA Opitz, WA Linke
The Journal of general physiology 126 (5), 461-480, 2005
3612005
IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression
A Sadik, LFS Patterson, S Öztürk, SR Mohapatra, V Panitz, PF Secker, ...
Cell 182 (5), 1252-1270. e34, 2020
3032020
Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR
UM Litzenburger, CA Opitz, F Sahm, KJ Rauschenbach, S Trump, ...
Oncotarget 5 (4), 1038, 2014
2972014
Gigantic variety: expression patterns of titin isoforms in striated muscles and consequences for myofibrillar passive stiffness
C Neagoe, CA Opitz, I Makarenko, WA Linke
Journal of Muscle Research & Cell Motility 24 (2), 175-189, 2003
2482003
Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart
CA Opitz, MC Leake, I Makarenko, V Benes, WA Linke
Circulation research 94 (7), 967-975, 2004
2232004
The therapeutic potential of targeting tryptophan catabolism in cancer
CA Opitz, LF Somarribas Patterson, SR Mohapatra, DL Dewi, A Sadik, ...
British journal of cancer 122 (1), 30-44, 2020
1842020
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress
F Sahm, I Oezen, CA Opitz, B Radlwimmer, A Von Deimling, T Ahrendt, ...
Cancer research 73 (11), 3225-3234, 2013
1802013
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress
F Sahm, I Oezen, CA Opitz, B Radlwimmer, A Von Deimling, T Ahrendt, ...
Cancer research 73 (11), 3225-3234, 2013
1802013
The indoleamine-2, 3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells
CA Opitz, UM Litzenburger, U Opitz, F Sahm, K Ochs, C Lutz, W Wick, ...
PloS one 6 (5), e19823, 2011
1742011
Damped elastic recoil of the titin spring in myofibrils of human myocardium
CA Opitz, M Kulke, MC Leake, C Neagoe, H Hinssen, RJ Hajjar, WA Linke
Proceedings of the National Academy of Sciences 100 (22), 12688-12693, 2003
1612003
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas
K Aslan, V Turco, J Blobner, JK Sonner, AR Liuzzi, NG Núñez, D De Feo, ...
Nature communications 11 (1), 931, 2020
1292020
Tryptophan degradation in autoimmune diseases
CA Opitz, W Wick, L Steinman, M Platten
Cellular and Molecular Life Sciences 64, 2542-2563, 2007
1142007
Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma
K Ochs, F Sahm, CA Opitz, TV Lanz, I Oezen, PO Couraud, ...
Journal of neuroimmunology 265 (1-2), 106-116, 2013
1042013
Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology
JK Sonner, M Keil, M Falk-Paulsen, N Mishra, A Rehman, M Kramer, ...
Nature communications 10 (1), 4877, 2019
792019
Pirfenidone inhibits TGF-β expression in malignant glioma cells
I Burghardt, F Tritschler, CA Opitz, B Frank, M Weller, W Wick
Biochemical and biophysical research communications 354 (2), 542-547, 2007
732007
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
MT Prentzell, U Rehbein, MC Sandoval, AS De Meulemeester, ...
Cell 184 (3), 655-674. e27, 2021
702021
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