Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use JF Atkins, G Loughran, PR Bhatt, AE Firth, PV Baranov Nucleic acids research 44 (15), 7007-7078, 2016 | 335 | 2016 |
Evidence of efficient stop codon readthrough in four mammalian genes G Loughran, MY Chou, IP Ivanov, I Jungreis, M Kellis, AM Kiran, ... Nucleic acids research 42 (14), 8928-8938, 2014 | 257 | 2014 |
Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits I Tachmazidou, D Süveges, JL Min, GRS Ritchie, J Steinberg, K Walter, ... The American Journal of Human Genetics 100 (6), 865-884, 2017 | 241* | 2017 |
Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome PR Bhatt, A Scaiola, G Loughran, M Leibundgut, A Kratzel, R Meurs, ... Science 372 (6548), 1306-1313, 2021 | 227 | 2021 |
Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1) IP Ivanov, G Loughran, MS Sachs, JF Atkins Proceedings of the National Academy of Sciences 107 (42), 18056-18060, 2010 | 169 | 2010 |
A case for “StopGo”: reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing … JF Atkins, NM Wills, G Loughran, CY Wu, K Parsawar, MD Ryan, ... Rna 13 (6), 803-810, 2007 | 167 | 2007 |
Insights into the mechanisms of eukaryotic translation gained with ribosome profiling DE Andreev, PBF O'Connor, G Loughran, SE Dmitriev, PV Baranov, ... Nucleic acids research 45 (2), 513-526, 2017 | 166 | 2017 |
The insulin-like growth factor-I–mTOR signaling pathway induces the mitochondrial pyrimidine nucleotide carrier to promote cell growth S Floyd, C Favre, FM Lasorsa, M Leahy, G Trigiante, P Stroebel, A Marx, ... Molecular biology of the cell 18 (9), 3545-3555, 2007 | 136 | 2007 |
Polyamine control of translation elongation regulates start site selection on antizyme inhibitor mRNA via ribosome queuing IP Ivanov, BS Shin, G Loughran, I Tzani, SK Young-Baird, C Cao, ... Molecular cell 70 (2), 254-264. e6, 2018 | 131 | 2018 |
Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5 G Loughran, MS Sachs, JF Atkins, IP Ivanov Nucleic acids research 40 (7), 2898-2906, 2012 | 125 | 2012 |
uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs IP Ivanov, G Loughran, JF Atkins Proceedings of the National Academy of Sciences 105 (29), 10079-10084, 2008 | 119 | 2008 |
Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth G Loughran, NC Healy, PA Kiely, M Huigsloot, NL Kedersha, R O'Connor Molecular biology of the cell 16 (4), 1811-1822, 2005 | 108 | 2005 |
Ribosomal frameshifting into an overlapping gene in the 2B-encoding region of the cardiovirus genome G Loughran, AE Firth, JF Atkins Proceedings of the National Academy of Sciences 108 (46), E1111-E1119, 2011 | 89 | 2011 |
Heme-binding protein HRG-1 is induced by insulin-like growth factor I and associates with the vacuolar H+-ATPase to control endosomal pH and receptor trafficking KM O'Callaghan, V Ayllon, J O'Keeffe, Y Wang, OT Cox, G Loughran, ... Journal of biological chemistry 285 (1), 381-391, 2010 | 80 | 2010 |
Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response G Loughran, I Jungreis, I Tzani, M Power, RI Dmitriev, IP Ivanov, M Kellis, ... Journal of Biological Chemistry 293 (12), 4434-4444, 2018 | 73 | 2018 |
AMD1 mRNA employs ribosome stalling as a mechanism for molecular memory formation MM Yordanova, G Loughran, AV Zhdanov, M Mariotti, SJ Kiniry, ... Nature 553 (7688), 356-360, 2018 | 73 | 2018 |
HMGB1 coordinates SASP‐related chromatin folding and RNA homeostasis on the path to senescence K Sofiadis, N Josipovic, M Nikolic, Y Kargapolova, N Übelmesser, ... Molecular systems biology 17 (6), e9760, 2021 | 62 | 2021 |
Gene expression profiles in cells transformed by overexpression of the IGF-I receptor G Loughran, M Huigsloot, PA Kiely, LM Smith, S Floyd, V Ayllon, ... Oncogene 24 (40), 6185-6193, 2005 | 56 | 2005 |
Systematic analysis of the PTEN 5′ leader identifies a major AUU initiated proteoform I Tzani, IP Ivanov, DE Andreev, RI Dmitriev, KA Dean, PV Baranov, ... Open biology 6 (5), 150203, 2016 | 53 | 2016 |
Non-AUG translation initiation in mammals DE Andreev, G Loughran, AD Fedorova, MS Mikhaylova, IN Shatsky, ... Genome Biology 23 (1), 111, 2022 | 48 | 2022 |