| Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 840 | 2015 |
| Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis YQ Cheng, GL Tang, B Shen Proceedings of the National Academy of Sciences 100 (6), 3149-3154, 2003 | 344 | 2003 |
| Novel Features of the Polysaccharide-Digesting Gliding Bacterium Flavobacterium johnsoniae as Revealed by Genome Sequence Analysis MJ McBride, G Xie, EC Martens, A Lapidus, B Henrissat, RG Rhodes, ... Applied and environmental microbiology 75 (21), 6864-6875, 2009 | 263 | 2009 |
| Target engagement and drug residence time can be observed in living cells with BRET MB Robers, ML Dart, CC Woodroofe, CA Zimprich, TA Kirkland, ... Nature communications 6 (1), 10091, 2015 | 248 | 2015 |
| Leinamycin biosynthesis revealing unprecedented architectural complexity for a hybrid polyketide synthase and nonribosomal peptide synthetase GL Tang, YQ Cheng, B Shen Chemistry & biology 11 (1), 33-45, 2004 | 203 | 2004 |
| Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP DHS Li, YS Chung, M Gloyd, E Joseph, R Ghirlando, GD Wright, ... Chemistry & biology 17 (9), 959-969, 2010 | 176 | 2010 |
| Genomics-Guided Discovery of Thailanstatins A, B, and C As Pre-mRNA Splicing Inhibitors and Antiproliferative Agents from Burkholderia thailandensis MSMB43 X Liu, S Biswas, MG Berg, CM Antapli, F Xie, Q Wang, MC Tang, GL Tang, ... Journal of natural products 76 (4), 685-693, 2013 | 143 | 2013 |
| Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities C Wang, LM Henkes, LB Doughty, M He, D Wang, FJ Meyer-Almes, ... Journal of natural products 74 (10), 2031-2038, 2011 | 139 | 2011 |
| Targeted Mutants of Cochliobolus carbonum Lacking the Two Major Extracellular Polygalacturonases JS Scott-Craig, YQ Cheng, F Cervone, G De Lorenzo, JW Pitkin, ... Applied and Environmental Microbiology 64 (4), 1497-1503, 1998 | 123 | 1998 |
| Deciphering the Biosynthetic Codes for the Potent Anti‐SARS‐CoV Cyclodepsipeptide Valinomycin in Streptomyces tsusimaensis ATCC 15141 YQ Cheng ChemBioChem 7 (3), 471-477, 2006 | 117 | 2006 |
| Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease E Leung, A Datti, M Cossette, J Goodreid, SE McCaw, M Mah, ... Chemistry & biology 18 (9), 1167-1178, 2011 | 116 | 2011 |
| Identification and Localization of the Gene Cluster Encoding Biosynthesis of the Antitumor Macrolactam Leinamycin in Streptomyces atroolivaceus S-140 YQ Cheng, GL Tang, B Shen Journal of bacteriology 184 (24), 7013-7024, 2002 | 107 | 2002 |
| A eukaryotic alanine racemase gene involved in cyclic peptide biosynthesis YQ Cheng, JD Walton Journal of biological chemistry 275 (7), 4906-4911, 2000 | 102 | 2000 |
| Biosynthesis of himastatin: assembly line and characterization of three cytochrome P450 enzymes involved in the post‐tailoring oxidative steps J Ma, Z Wang, H Huang, M Luo, D Zuo, B Wang, A Sun, YQ Cheng, ... Angewandte Chemie International Edition 34 (50), 7797-7802, 2011 | 92 | 2011 |
| Characterization of a Gene Cluster Responsible for the Biosynthesis of Anticancer Agent FK228 in Chromobacterium violaceum No. 968 YQ Cheng, M Yang, AM Matter Applied and environmental microbiology 73 (11), 3460-3469, 2007 | 78 | 2007 |
| An FAD-dependent pyridine nucleotide-disulfide oxidoreductase is involved in disulfide bond formation in FK228 anticancer depsipeptide C Wang, SR Wesener, H Zhang, YQ Cheng Chemistry & biology 16 (6), 585-593, 2009 | 75 | 2009 |
| Genome-guided discovery of diverse natural products from Burkholderia sp. X Liu, YQ Cheng Journal of Industrial Microbiology and Biotechnology 41 (2), 275-284, 2014 | 71 | 2014 |
| Type I polyketide synthases that require discrete acyltransferases YQ Cheng, JM Coughlin, SK Lim, B Shen Methods in enzymology 459, 165-186, 2009 | 70 | 2009 |
| Activation of ClpP protease by ADEP antibiotics: insights from hydrogen exchange mass spectrometry MA Sowole, JA Alexopoulos, YQ Cheng, J Ortega, L Konermann Journal of molecular biology 425 (22), 4508-4519, 2013 | 60 | 2013 |
| Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140: Discrete, monofunctional adenylation … GL Tang, YQ Cheng, B Shen Journal of Biological Chemistry 282 (28), 20273-20282, 2007 | 60 | 2007 |
Ben ShenThe Scripps Research InstituteVerified email at scripps.edu
