Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells MA Antonyak, B Li, LK Boroughs, JL Johnson, JE Druso, KL Bryant, ... Proceedings of the National Academy of Sciences 108 (12), 4852-4857, 2011 | 541 | 2011 |
Cancer cell-derived microvesicles induce transformation by transferring tissue transglutaminase and fibronectin to recipient cells MA Antonyak, B Li, LK Boroughs, JL Johnson, JE Druso, KL Bryant, ... Proceedings of the National Academy of Sciences 108 (12), 4852-4857, 2011 | 541 | 2011 |
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids Y Han, X Duan, L Yang, BE Nilsson-Payant, P Wang, F Duan, X Tang, ... Nature 589 (7841), 270-275, 2021 | 465 | 2021 |
Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors N Vasan, P Razavi, JL Johnson, H Shao, H Shah, A Antoine, E Ladewig, ... Science 366 (6466), 714-723, 2019 | 223 | 2019 |
An atlas of substrate specificities for the human serine/threonine kinome JL Johnson, TM Yaron, EM Huntsman, A Kerelsky, J Song, A Regev, ... Nature 613 (7945), 759-766, 2023 | 163 | 2023 |
Dietary fructose improves intestinal cell survival and nutrient absorption SR Taylor, S Ramsamooj, RJ Liang, A Katti, R Pozovskiy, N Vasan, ... Nature 597 (7875), 263-267, 2021 | 160 | 2021 |
New insights into how the Rho guanine nucleotide dissociation inhibitor regulates the interaction of Cdc42 with membranes JL Johnson, JW Erickson, RA Cerione Journal of biological chemistry 284 (35), 23860-23871, 2009 | 123 | 2009 |
Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops T Freisinger, B Klünder, J Johnson, N Müller, G Pichler, G Beck, ... Nature communications 4 (1), 1807, 2013 | 120 | 2013 |
Identification of candidate COVID-19 therapeutics using hPSC-derived lung organoids Y Han, L Yang, X Duan, F Duan, BE Nilsson-Payant, TM Yaron, P Wang, ... BioRxiv, 2020.05. 05.079095, 2020 | 98 | 2020 |
Interactions between epigenetics and metabolism in cancers J Yun, JL Johnson, CL Hanigan, JW Locasale Frontiers in oncology 2, 163, 2012 | 93 | 2012 |
Phosphatidylinositol-5-phosphate 4-kinases regulate cellular lipid metabolism by facilitating autophagy MR Lundquist, MD Goncalves, RM Loughran, E Possik, T Vijayaraghavan, ... Molecular cell 70 (3), 531-544. e9, 2018 | 77 | 2018 |
A chemoproteomic strategy for direct and proteome-wide covalent inhibitor target-site identification CM Browne, B Jiang, SB Ficarro, ZM Doctor, JL Johnson, JD Card, ... Journal of the American Chemical Society 141 (1), 191-203, 2018 | 72 | 2018 |
C-terminal di-arginine motif of Cdc42 protein is essential for binding to phosphatidylinositol 4, 5-bisphosphate-containing membranes and inducing cellular transformation JL Johnson, JW Erickson, RA Cerione Journal of Biological Chemistry 287 (8), 5764-5774, 2012 | 62 | 2012 |
A unique role for heat shock protein 70 and its binding partner tissue transglutaminase in cancer cell migration LK Boroughs, MA Antonyak, JL Johnson, RA Cerione Journal of Biological Chemistry 286 (43), 37094-37107, 2011 | 58 | 2011 |
Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription JK Rimel, ZC Poss, B Erickson, ZL Maas, CC Ebmeier, JL Johnson, ... Genes & development 34 (21-22), 1452-1473, 2020 | 54 | 2020 |
Coagulation factors directly cleave SARS-CoV-2 spike and enhance viral entry ER Kastenhuber, M Mercadante, B Nilsson-Payant, JL Johnson, ... Elife 11, e77444, 2022 | 52 | 2022 |
EGF-receptor specificity for phosphotyrosine-primed substrates provides signal integration with Src MJ Begley, C Yun, CA Gewinner, JM Asara, JL Johnson, AJ Coyle, ... Nature structural & molecular biology 22 (12), 983-990, 2015 | 48 | 2015 |
Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1) N Balasuriya, NE Davey, JL Johnson, H Liu, KK Biggar, LC Cantley, ... Journal of Biological Chemistry 295 (24), 8120-8134, 2020 | 41 | 2020 |
SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2 TM Yaron, BE Heaton, TM Levy, JL Johnson, TX Jordan, BM Cohen, ... | 39 | 2020 |
Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7 Y Zhou, JL Johnson, RA Cerione, JW Erickson Biochemistry 52 (25), 4354-4363, 2013 | 35 | 2013 |