Robert James Thomas
Robert James Thomas
Wolfson School, Loughborough University
Verified email at
Cited by
Cited by
Expansion of human mesenchymal stem cells on microcarriers
CJ Hewitt, K Lee, AW Nienow, RJ Thomas, M Smith, CR Thomas
Biotechnology letters 33, 2325-2335, 2011
Automated, scalable culture of human embryonic stem cells in feeder‐free conditions
RJ Thomas, D Anderson, A Chandra, NM Smith, LE Young, D Williams, ...
Biotechnology and Bioengineering 102 (6), 1636-1644, 2009
The effect of three-dimensional co-culture of hepatocytes and hepatic stellate cells on key hepatocyte functions in vitro
RJ Thomas, R Bhandari, DA Barrett, AJ Bennett, JR Fry, D Powe, ...
Cells Tissues Organs 181 (2), 67-79, 2005
Human-induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient-dependent efficiency
D Hallam, G Hilgen, B Dorgau, L Zhu, M Yu, S Bojic, P Hewitt, M Schmitt, ...
Stem Cells 36 (10), 1535-1551, 2018
Current understanding and challenges in bioprocessing of stem cell-based therapies for regenerative medicine
E Ratcliffe, RJ Thomas, DJ Williams
British medical bulletin 100 (1), 137, 2011
Manufacture of a human mesenchymal stem cell population using an automated cell culture platform
RJ Thomas, A Chandra, Y Liu, PC Hourd, PP Conway, DJ Williams
Cytotechnology 55, 31-39, 2007
Application of process quality engineering techniques to improve the understanding of the in vitro processing of stem cells for therapeutic use
RJ Thomas, PC Hourd, DJ Williams
Journal of biotechnology 136 (3-4), 148-155, 2008
Precision manufacturing for clinical-quality regenerative medicines
DJ Williams, RJ Thomas, PC Hourd, A Chandra, E Ratcliffe, Y Liu, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2012
Automated, serum-free production of CTX0E03: a therapeutic clinical grade human neural stem cell line
RJ Thomas, AD Hope, P Hourd, M Baradez, EA Miljan, JD Sinden, ...
Biotechnology letters 31, 1167-1172, 2009
A Novel Automated Bioreactor for Scalable Process Optimisation of Haematopoietic Stem Cell Culture
E Ratcliffe, KE Glen, VL Workman, AJ Stacey, RJ Thomas
Journal of Biotechnology, 2012
Hepatic stellate cells on poly (DL-lactic acid) surfaces control the formation of 3D hepatocyte co-culture aggregates in vitro.
RJ Thomas, A Bennett, B Thomson, KM Shakesheff
European cells & materials 11, 16-26; discussion 26, 2006
Cell culture automation and quality engineering: a necessary partnership to develop optimized manufacturing processes for cell-based therapies
RJ Thomas, A Chandra, PC Hourd, DJ Williams
JALA: Journal of the Association for Laboratory Automation 13 (3), 152-158, 2008
Mesenchymal stem cell isolation from human umbilical cord tissue: understanding and minimizing variability in cell yield for process optimization
A Iftimia-Mander, P Hourd, R Dainty, RJ Thomas
Biopreservation and biobanking 11 (5), 291-298, 2013
Investigating the feasibility of scale up and automation of human induced pluripotent stem cells cultured in aggregates in feeder free conditions
FAC Soares, A Chandra, RJ Thomas, RA Pedersen, L Vallier, DJ Williams
Journal of biotechnology 173, 53-58, 2014
The productivity limit of manufacturing blood cell therapy in scalable stirred bioreactors
R Bayley, F Ahmed, K Glen, M McCall, A Stacey, R Thomas
Journal of tissue engineering and regenerative medicine 12 (1), e368-e378, 2018
Comparability: Manufacturing, characterization and controls, report of a UK Regenerative Medicine Platform pluripotent stem cell platform workshop, Trinity Hall, Cambridge, 14 …
DJ Williams, R Archer, P Archibald, I Bantounas, R Baptista, R Barker, ...
Regenerative medicine 11 (5), 483-492, 2016
A quality-by-design approach to risk reduction and optimization for human embryonic stem cell cryopreservation processes
PD Mitchell, E Ratcliffe, P Hourd, DJ Williams, RJ Thomas
Tissue Engineering Part C: Methods 20 (12), 941-950, 2014
Production of erythrocytes from directly isolated or Delta1 Notch ligand expanded CD34+ hematopoietic progenitor cells: process characterization, monitoring and implications …
KE Glen, VL Workman, F Ahmed, E Ratcliffe, AJ Stacey, RJ Thomas
Cytotherapy 15 (9), 1106-1117, 2013
A mechanistic model of erythroblast growth inhibition providing a framework for optimisation of cell therapy manufacturing
KE Glen, EA Cheeseman, AJ Stacey, RJ Thomas
Biochemical Engineering Journal 133, 28-38, 2018
Application of response surface methodology to maximize the productivity of scalable automated human embryonic stem cell manufacture
E Ratcliffe, P Hourd, J Guijarro-Leach, E Rayment, DJ Williams, ...
Regenerative Medicine 8 (1), 39-48, 2013
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