| Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer HW Cheung, GS Cowley, BA Weir, JS Boehm, S Rusin, JA Scott, A East, ... Proceedings of the National Academy of Sciences 108 (30), 12372-12377, 2011 | 500 | 2011 |
| Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies GS Cowley, BA Weir, F Vazquez, P Tamayo, JA Scott, S Rusin, ... Scientific data 1 (1), 1-12, 2014 | 466 | 2014 |
| R-DeeP: proteome-wide and quantitative identification of RNA-dependent proteins by density gradient ultracentrifugation M Caudron-Herger, SF Rusin, ME Adamo, J Seiler, VK Schmid, E Barreau, ... Molecular cell 75 (1), 184-199. e10, 2019 | 92 | 2019 |
| Identification of candidate casein kinase 2 substrates in mitosis by quantitative phosphoproteomics SF Rusin, ME Adamo, AN Kettenbach Frontiers in cell and developmental biology 5, 97, 2017 | 76 | 2017 |
| Quantitative phosphoproteomics reveals new roles for the protein phosphatase PP6 in mitotic cells SF Rusin, KA Schlosser, ME Adamo, AN Kettenbach Science signaling 8 (398), rs12-rs12, 2015 | 76 | 2015 |
| Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria SM Nowinski, A Solmonson, SF Rusin, JA Maschek, CL Bensard, ... Elife 9, e58041, 2020 | 72 | 2020 |
| Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins I Nasa, SF Rusin, AN Kettenbach, GB Moorhead Science signaling 11 (530), eaai8669, 2018 | 72 | 2018 |
| Optimized workflow for multiplexed phosphorylation analysis of TMT-labeled peptides using high-field asymmetric waveform ion mobility spectrometry DK Schweppe, SF Rusin, SP Gygi, JA Paulo Journal of proteome research 19 (1), 554-560, 2019 | 61 | 2019 |
| Cyclin A/Cdk1 modulates Plk1 activity in prometaphase to regulate kinetochore-microtubule attachment stability AMG Dumitru, SF Rusin, AEM Clark, AN Kettenbach, DA Compton Elife 6, e29303, 2017 | 54 | 2017 |
| PP1: tautomycetin complex reveals a path toward the development of PP1-specific inhibitors MS Choy, M Swingle, B D’Arcy, K Abney, SF Rusin, AN Kettenbach, ... Journal of the American Chemical Society 139 (49), 17703-17706, 2017 | 45 | 2017 |
| HOPS catalyzes the interdependent assembly of each vacuolar SNARE into a SNARE complex A Orr, H Song, SF Rusin, AN Kettenbach, W Wickner Molecular biology of the cell 28 (7), 975-983, 2017 | 44 | 2017 |
| Mechanisms connecting the conserved protein kinases Ssp1, Kin1, and Pom1 in fission yeast cell polarity and division ME Lee, SF Rusin, N Jenkins, AN Kettenbach, JB Moseley Current Biology 28 (1), 84-92. e4, 2018 | 37 | 2018 |
| Crystal structures and mutagenesis of PPP-family ser/thr protein phosphatases elucidate the selectivity of cantharidin and novel norcantharidin-based inhibitors of PP5C D Chattopadhyay, MR Swingle, EA Salter, E Wood, B D’Arcy, C Zivanov, ... Biochemical pharmacology 109, 14-26, 2016 | 35 | 2016 |
| Yeast vacuolar HOPS, regulated by its kinase, exploits affinities for acidic lipids and Rab: GTP for membrane binding and to catalyze tethering and fusion A Orr, W Wickner, SF Rusin, AN Kettenbach, M Zick Molecular biology of the cell 26 (2), 305-315, 2015 | 34 | 2015 |
| The Candida albicans Cdk8-dependent phosphoproteome reveals repression of hyphal growth through a Flo8-dependent pathway JM Hollomon, Z Liu, SF Rusin, NP Jenkins, AK Smith, K Koeppen, ... PLoS Genetics 18 (1), e1009622, 2022 | 11 | 2022 |
| Abstract LB118: Mechanisms underlying synergistic activity in MYD88MTDLBCL of KT-413, a targeted degrader of IRAK4 and IMiD substrate CR Klaus, SF Rusin, K Sharma, S Bhaduri, MM Weiss, AA McDonald, ... Cancer Research 81 (13_Supplement), LB118-LB118, 2021 | 5 | 2021 |
| Inducible protein degradation as a strategy to identify Phosphoprotein Phosphatase 6 substrates in RAS-mutant colorectal cancer cells NC Mariano, SF Rusin, I Nasa, AN Kettenbach Molecular & Cellular Proteomics 22 (8), 2023 | 4 | 2023 |
| KYM‐001, A FIRST‐IN‐CLASS ORAL IRAK4 PROTEIN DEGRADER, INDUCES TUMOR REGRESSION IN XENOGRAFT MODELS OF MYD88‐MUTANT ABC DLBCL ALONE AND IN COMBINATION WITH BTK INHIBITION J Kelleher, V Campbell, J Chen, J Gollob, N Ji, H Kamadurai, C Klaus, ... Hematological Oncology 37, 129-129, 2019 | 4 | 2019 |
| Ktx-120, a Novel Irakimid Degrader of IRAK4 and IMiD Substrates Shows Preferential Activity and Induces Regressions in MYD88-Mutant DLBCL CDX and PDX Models D Walker, M Mayo, C Klaus, D Chen, S Bhaduri, K Sharma, S Rusin, ... Blood 136, 41, 2020 | 3 | 2020 |
| Aurora B opposes PP1 function in mitosis through phosphorylation of the conserved RVxF binding motif in PP1 regulatory proteins I Nasa, SF Rusin, AN Kettenbach, GB Moorhead Science signaling 11 (530), 2018 | 2 | 2018 |
