CSF-1R inhibition alters macrophage polarization and blocks glioma progression SM Pyonteck, L Akkari, AJ Schuhmacher, RL Bowman, L Sevenich, ... Nature medicine 19 (10), 1264-1272, 2013 | 2332 | 2013 |
Single-cell map of diverse immune phenotypes in the breast tumor microenvironment E Azizi, AJ Carr, G Plitas, AE Cornish, C Konopacki, S Prabhakaran, ... Cell 174 (5), 1293-1308. e36, 2018 | 1734 | 2018 |
Wishbone identifies bifurcating developmental trajectories from single-cell data M Setty, MD Tadmor, S Reich-Zeliger, O Angel, TM Salame, P Kathail, ... Nature biotechnology 34 (6), 637-645, 2016 | 651 | 2016 |
Characterization of cell fate probabilities in single-cell data with Palantir M Setty, V Kiseliovas, J Levine, A Gayoso, L Mazutis, D Pe’Er Nature biotechnology 37 (4), 451-460, 2019 | 516 | 2019 |
CellRank for directed single-cell fate mapping M Lange, V Bergen, M Klein, M Setty, B Reuter, M Bakhti, H Lickert, ... Nature methods 19 (2), 159-170, 2022 | 480 | 2022 |
Ibrutinib Resistance in Chronic Lymphocytic Leukemia R Furman, P Lu, M Setty, A Perez, J Racchumi, G Xu, H Wu, J Ma, ... New England Journal of Medicine, 2352-2354, 2014 | 375 | 2014 |
Genomic safe harbors permit high β-globin transgene expression in thalassemia induced pluripotent stem cells EP Papapetrou, G Lee, N Malani, M Setty, I Riviere, LMS Tirunagari, ... Nature biotechnology 29 (1), 73-78, 2011 | 375 | 2011 |
Regenerative lineages and immune-mediated pruning in lung cancer metastasis AM Laughney, J Hu, NR Campbell, SF Bakhoum, M Setty, VP Lavallée, ... Nature medicine 26 (2), 259-269, 2020 | 356 | 2020 |
The emergent landscape of the mouse gut endoderm at single-cell resolution S Nowotschin, M Setty, YY Kuo, V Liu, V Garg, R Sharma, CS Simon, ... Nature 569 (7756), 361-367, 2019 | 348 | 2019 |
A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL) KJ Mavrakis, J Van Der Meulen, AL Wolfe, X Liu, E Mets, T Taghon, ... Nature genetics 43 (7), 673-678, 2011 | 329 | 2011 |
Epigenomic-guided mass cytometry profiling reveals disease-specific features of exhausted CD8 T cells B Bengsch, T Ohtani, O Khan, M Setty, S Manne, S O’Brien, PF Gherardini, ... Immunity 48 (5), 1029-1045. e5, 2018 | 300 | 2018 |
Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling JM Chan, S Zaidi, JR Love, JL Zhao, M Setty, KM Wadosky, A Gopalan, ... Science 377 (6611), 1180-1191, 2022 | 188 | 2022 |
Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer’s disease SR Guttikonda, L Sikkema, J Tchieu, N Saurat, RM Walsh, O Harschnitz, ... Nature Neuroscience 24 (3), 343-354, 2021 | 174 | 2021 |
BCL6 positively regulates AID and germinal center gene expression via repression of miR-155 K Basso, C Schneider, Q Shen, AB Holmes, M Setty, C Leslie, ... Journal of Experimental Medicine 209 (13), 2455-2465, 2012 | 155 | 2012 |
Inferring transcriptional and microRNA‐mediated regulatory programs in glioblastoma M Setty, K Helmy, AA Khan, J Silber, A Arvey, F Neezen, P Agius, JT Huse, ... Molecular systems biology 8 (1), 605, 2012 | 111 | 2012 |
MicroRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas C Schneider, M Setty, AB Holmes, RL Maute, CS Leslie, L Mussolin, ... Proceedings of the National Academy of Sciences 111 (22), 8185-8190, 2014 | 103 | 2014 |
Negative co-stimulation constrains T cell differentiation by imposing boundaries on possible cell states SC Wei, R Sharma, NAAS Anang, JH Levine, Y Zhao, JJ Mancuso, ... Immunity 50 (4), 1084-1098. e10, 2019 | 100 | 2019 |
SEACells infers transcriptional and epigenomic cellular states from single-cell genomics data S Persad, ZN Choo, C Dien, I Masilionis, R Chaligné, T Nawy, CC Brown, ... Nature Biotechnology, 2022.04. 02.486748, 2023 | 96* | 2023 |
Early enhancer establishment and regulatory locus complexity shape transcriptional programs in hematopoietic differentiation AJ González, M Setty, CS Leslie Nature genetics 47 (11), 1249-1259, 2015 | 94 | 2015 |
SeqGL identifies context-dependent binding signals in genome-wide regulatory element maps M Setty, CS Leslie PLoS computational biology 11 (5), e1004271, 2015 | 79 | 2015 |